Critical Care

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This article is part of the supplement: Analgesia and sedation in the intensive care unit

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The place for short-acting opioids: special emphasis on remifentanil

Wolfram Wilhelm* and Sascha Kreuer

Critical Care 2008, 12(Suppl 3):S5 doi:10.1186/cc6152

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Research   Open Access Highly Accessed

Remifentanil discontinuation and subsequent intensive care unit-acquired infection: a cohort study

Saad Nseir, Jérémy Hoel, Guillaume Grailles, Aude Soury-Lavergne, Christophe Di Pompeo, Daniel Mathieu, Alain Durocher Critical Care 2009, 13:R60 (21 April 2009)

Remifentanil discontinuation is associated with an increased risk of ICU-acquired infection, an observation that reiterates previous reports on the negative effects of opioid withdrawal on the immune system.

Review   Free Highly Accessed

Strategies to optimize analgesia and sedation

William D Schweickert, John P Kress Critical Care 2008, 12(Suppl 3):S6 (14 May 2008)

Introduction   Free Highly Accessed

Analgesia and sedation in the intensive care unit: an overview of the issues

Curtis N Sessler, Wolfram Wilhelm Critical Care 2008, 12(Suppl 3):S1 (14 May 2008)