Table 1

28-Day all-cause mortality in TFPI-treated and placebo-treated patients

Overall

INR ≥1.2
 Placebo
 TFPI
 P
Positive blood culture
     n
 257
 278
     Total (%)
 29.4
 31.6
 0.054
     Mortality (%)
 35.4
 27.7
Positive other
     n
 387
 370
     Total (%)
 44.3
 42.0
 0.94
     Mortality (%)
 35.1
 35.4
Negative culture/not done
     n
 230
 232
     Total (%)
 26.3
 26.4
 0.02
     Mortality (%)
 30.0
 40.1

Presented are 28-day all-cause mortality rates in TFPI and placebo-treated patients with positive blood cultures, other documented infections, and negative culture or undocumented infections. INR, international normalized ratio; TFPI, Tissue factor pathway inhibitor.

Laterre Critical Care 2008 12(Suppl 6):S4   doi:10.1186/cc7027