Table 2

28-Day all-cause mortality in patients with and those without heparin prophylaxis

Any heparin

No heparin

INR ≥1.2

Placebo

TFPI

P

Placebo

TFPI

P

Positive blood culture

n

162

174

0.31

95

104

0.05

Mortality (%)

32.7

28.2

40.0

26.9

Positive other

n

271

267

0.39

116

103

0.24

Mortality (%)

30.6

34.5

45.7

37.9

Negative culture/not done

n

167

159

0.01

63

73

0.98

Mortality (%)

25.7

39.6

41.3

41.1

Presented are 28-day all-cause mortality rates in patients with or without heparin prophylaxis during the study drug infusion period and with positive blood cultures, other documented infections, and negative culture or undocumented infections. INR, international normalized ratio; TFPI, Tissue factor pathway inhibitor.

Laterre Critical Care 2008 12(Suppl 6):S4   doi:10.1186/cc7027