Table 3

Results of thromboelastometry

Parameter

Normal ranges

0 hours

12 hours

24 hours

36 hours

48 hours

Discharge

Spearman

r

P

CT-EXTEM

42 to 74

64.9 ± 7.6

66.0 ± 10.6

61.7 ± 9.6

63.7 ± 7.2

61.9 ± 7.3

57.4 ± 4.6*

0.09

0.36

CT-INTEM

137 to 246

195.9 ± 25.8

201.0 ± 31.4

199.8 ± 36.7

213.2 ± 41.1

216.3 ± 43.8

206.7 ± 40.6

CT-HEPTEM

137 to 246

197.1 ± 39.3

217.2 ± 58.1

212.2 ± 47.7

212.4 ± 40.0

205.8 ± 29.6

192.8 ± 34.2

CFT-EXTEM

46 to 148

97.0 ± 62.6

103.6 ± 79.2

99.3 ± 61.0

100.4 ± 64.8

94.5 ± 54.9

62.6 ± 30.7*

0.64

0.001

Alpha-EXTEM

63 to 81

73.9 ± 7.8

74.3 ± 7.1

74.0 ± 6.9

73.7 ± 6.8

74.5 ± 5.9

78.3 ± 4.1

-0.58

0.001

MCF-EXTEM

49 to 71

62.1 ± 11.2

62.1 ± 12.6

62.1 ± 12.1

62.1 ± 12.4

62.7 ± 11.6

67.4 ± 9.0*

-0.63

0.001

MCF-INTEM

52 to 72

63.7 ± 8.0

63.2 ± 7.6

61.9 ± 8.3

64.1 ± 7.7

64.6 ± 8.1

66.9 ± 8.4

MCF-HEPTEM

52 to 72

61.0 ± 8.9

59.6 ± 8.0

59.1 ± 9.4

60.6 ± 9.2

61.5 ± 8.4

64.1 ± 7.8*

Spearman rank correlation (r) is between the continuous values of Sequential Organ Failure Assessment (SOFA) score with thromboelastometric variables. *P < 0.05, versus baseline. alpha angle (°); CFT, clot formation time (seconds); CT, clotting time (seconds); EXTEM, activation of coagulation with tissue factor; HEPTEM, inhibition of heparin with heparinase; INTEM, activation of coagulation with thromboplastin; MCF, maximal clot firmness (mm).

Daudel et al. Critical Care 2009 13:R42   doi:10.1186/cc7765