Table 3

Lung tissue concentrations of inflammatory chemokines after inhaling H₂S during normothermia or hypothermia

Control, 38°C

H₂S, 38°C

Control, 27°C

H₂S, 27°C

TNFα (pg/mg protein)

67 (52 to 90)

75 (60 to 88)

76 (54 to 88)

71 (60 to 81)

IL-6 (pg/mg protein)

449 (264 to 713)

366 (252 to 483)

338 (140 to 500)

260 (192 to 339)*

MCP-1 (pg/mg protein)

194 (102 to 280)

114 (77 to 138)*

99 (68 to 168)*

106 (48 to 150)*

MIP-2 (pg/mg protein)

613 (278 to 1049)

284 (214 to 357)*

306 (231 to 376)*

283 (248 to 373)*

KC (pg/mg protein)

435 (268 to 602)

296 (255 to 332)*

309 (217 to 401)*

329 (301 to 366)*

Lung tissue concentrations of monocyte chemotactic protein-1 (MCP-1), macrophage-inflammatory protein-2 (MIP-2), growth-related oncogen/keratinocyte-derived chemokine (KC), TNF α, and IL-6 after inhaling hydrogen sulfide (H₂S) (100 ppm over 5 hours) during normothermia (38°C) or hypothermia (27°C) [83]. Data presented as median (range), n = 5 in each group. *P < 0.05 versus control, 38°C.

Wagner et al. Critical Care 2009 13:213   doi:10.1186/cc7700