Table 2 |
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Mean inspiratory airway pressure (Paw mean), expiratory (PTPexp), inspiratory (PTPinsp) and PEEP (PTPPEEP) pressure time products at a respiratory rate of 30 breaths per minute and a ventilatory rate of 15 breaths per minute |
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Δ pressure |
5 cmH20 |
15 cmH20 |
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Effort |
low |
high |
low |
high |
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Normal lung condition |
Paw mean (cmH2O) |
HF-BiPAP nBBIPAPBiPulse |
10.5 ± 0.9 |
12.1 ± 0.2 |
14.6 ± 2.9 |
15.6 ± 2.4 |
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BiVent |
10.6 ± 1.2 |
11.8 ± 1.8 |
15.3 ± 2.8 |
15.5 ± 2.2 |
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PTPPEEP. (cmH20/sec) |
HF-BiPAP |
-0.1 ± 0.1 |
-0.2 ± 0.2 |
-0.2 ± 0.1 |
-0.1 ± 0.1 |
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BiVent |
0 ± 0 |
-0.2 ± 0.1 |
0 ± 0 |
-0.3 ± 0.2 |
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PTP insp. (cmH20/sec) |
HF-BiPAP |
1.2 ± 0.8 |
1.1 ± 0.7 |
3.3 ± 2.6 |
4 ± 1.7 |
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BiVent |
1.3 ± 1.2 |
1.8 ± 1.5 |
2.7 ± 1.7 |
3.5 ± 2.4 |
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PTP exp. (cmH20/sec) |
HF-BiPAP e |
7 ± 6.1 |
3.8 ± 1.8 |
10 ± 6.4 |
4.2 ± 1.8 |
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BiVent |
7.2 ± 3.2 |
7.0 ± 0.9 |
11.8 ± 3.9 |
4.6 ± 1.8 |
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Obstructive lung condition |
Paw mean (cmH2O) |
HF-BiPAP |
10.4 ± 1 |
10.4 ± 0.7 |
15 ± 3.8 |
16.3 ± 3.4 |
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BiVent |
10.3 ± 2.3 |
11 ± 3.5 |
15.4 ± 7.2 |
15.4 ± 4.1 |
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PTPPEEP. (cmH20/sec) |
HF-BiPAP |
0 ± 0 |
-0.13 ± 0.15 |
-0.01 ± 0.05 |
-0.05 ± 0.16 |
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BiVent |
0 ± 0 |
-0.2 ± 0.01 |
-0.02 ± 0.04 |
-0.2 ± 0.24 |
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PTP insp. (cmH20/sec) |
HF-BiPAP |
1.0 ± 0.9 |
2.04 ± 1.4 |
3.6 ± 2.6 |
3.6 ± 2 |
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BiVent |
1.3 ± 1.1 |
2.5 ± 2.4 |
2.8 ± 2.1 |
3.1 ± 2.7 |
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PTP exp. (cmH20/sec) |
HF-BiPAP |
3.8 ± 2.5 |
9.8 ± 4.8 |
2.9 ± 1.7 |
10.1 ± 8.1 |
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BiVent |
7.2 ± 3.2 |
10.9 ± 4.1 |
3.8 ± 1.9 |
10.3 ± 3.8 |
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Restrictive lung condition |
Paw mean (cmH2O) |
HF-BiPAP |
10.5 ± 1 |
11.7 ± 0.1 |
14.7 ± 2.2 |
14.7 ± 2.3 |
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BiVent |
9.9 ± 1 |
11.1 ± 1 |
15 ± 2.8 |
15.4 ± 4.7 |
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PTPPEEP. (cmH20/sec) |
HF-BiPAP |
-0.16 ± 0.2 |
-0.1 ± 0.2 |
0.09 ± 0.1 |
-0.09 ± 0.1 |
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BiVent |
-0.35 ± 0.4 |
-0.24 ± 0.2 |
-0.16 ± 0.2 |
-0.16 ± 0.2 |
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PTP insp. (cmH20/sec) |
HF-BiPAP |
1 ± 0.6 |
1.2 ± 0.2 |
3.3 ± 2 |
3.4 ± 2 |
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BiVent |
2 ± 1.5 |
1.4 ± 0.9 |
3.3 ± 2.9 |
1.9 ± 2.4 |
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PTP exp. (cmH20/sec) |
HF-BiPAP |
3.7 ± 1.7 |
7.8 ± 3.7 |
4.2 ± 2.4 |
9.4 ± 4.5 |
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BiVent |
5 ± 1 |
7.2 ± 4.9 |
7.5 ± 3.2 |
10.1 ± 5.5 |
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Measurements were made in normal (compliance 90 ml/cmH2O, resistance 3 cmH2O/l/s), obstructive (compliance 90 ml/cmH2O, resistance 15 cmH2O/l/s) and restrictive (compliance 30 ml/cmH2O, resistance 3 cmH2O/l/s) lung conditions, during varying delta pressure (Δ 5 and Δ 15 cmH2O) and inspiratory efforts (low: 2.5 cmH2O, high: 10 cmH2O) at a set positive end-expiratory pressure of 8 cmH2O. HF-BiPAP = high flow biphasic positive airway pressure ventilation; BiVent = biphasic positive airway pressure delivered by a ventilator; PSV = pressure support ventilation by a ventilator. |
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Moerer et al. Critical Care 2009 13:R85 doi:10.1186/cc7907 |
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