Critical Care

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Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill

Houman Khosravani, Reza Shahpori, H Thomas Stelfox, Andrew W Kirkpatrick and Kevin B Laupland*

Critical Care 2009, 13:R90 doi:10.1186/cc7918

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Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: A systematic review

Ole Kruse, Niels Grunnet, Charlotte Barfod Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2011, 19:74 (28 December 2011)

Research   Open Access Highly Accessed

Dynamic lactate indices as predictors of outcome in critically ill patients

Alistair Nichol, Michael Bailey, Moritoki Egi, Ville Pettila, Craig French, Edward Stachowski, Michael C Reade, David Cooper, Rinaldo Bellomo Critical Care 2011, 15:R242 (20 October 2011)

Measuring the magnitude, duration and trend of changes in blood lactate concentration over time may be more useful in predicting outcome in critically ill patients than a single measurement taken on admission.

Research   Open Access Highly Accessed

Relative hyperlactatemia and hospital mortality in critically ill patients: a retrospective multi-centre study

Alistair D Nichol, Moritoki Egi, Ville Pettila, Rinaldo Bellomo, Craig French, Graeme Hart, Andrew Davies, Edward Stachowski, Michael C Reade, Michael Bailey, David James Cooper Critical Care 2010, 14:R25 (24 February 2010)

Intensive care unit blood lactate concentrations are independently associated with increased hospital mortality within currently defined ‘normal’ levels, allowing for easier diagnosis of critically ill patients at higher risk of death.

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The riddle of hyperlactatemia

Guillermo Gutierrez, Jeffrey D Williams Critical Care 2009, 13:176 (12 August 2009)