Table 4 |
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|
Changes in microvascular variables as mean arterial pressure was increased from 65 mmHg to 85 mmHg with norepinephrine |
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|
Mean arterial blood pressure |
ANOVA |
Linear trend |
|||
|
|
|||||
|
65 mmHg |
75 mmHg |
85 mmHg |
P |
P |
|
|
|
|||||
|
Vascular density (vessels/mm2) |
|||||
|
Large diameter vessels |
11 ± 1 |
10 ± 3 |
10 ± 3 |
0.81 |
0.61 |
|
Medium diameter vessels |
15 ± 3 |
16 ± 4 |
16 ± 4 |
0.82 |
0.53 |
|
Small diameter vessels |
24 ± 8 |
23 ± 8 |
22 ± 1 |
0.09 |
0.03 |
|
Microvascular flow index |
|||||
|
Large diameter vessels |
2.3 ± 0.6 |
2.3 ± 0.8 |
2.2 ± 0.8 |
0.34 |
0.16 |
|
Medium diameter vessels |
2.2 ± 0.7 |
2.2 ± 0.7 |
2.1 ± 0.9 |
0.79 |
0.52 |
|
Small diameter vessels |
2.1 ± 0.7 |
2.2 ± 0.7 |
2.0 ± 0.8 |
0.69 |
0.47 |
|
Perfused vessels (%) |
|||||
|
Large diameter vessels |
82 ± 21 |
80 ± 28 |
87 ± 6 |
0.46 |
0.40 |
|
Medium diameter vessels |
77 ± 27 |
77 ± 29 |
77 ± 6 |
0.98 |
1.00 |
|
Small diameter vessels |
72 ± 26 |
71 ± 27 |
67 ± 32 |
0.55 |
0.38 |
|
Total vessels |
75 ± 25 |
75 ± 27 |
76 ± 4 |
0.92 |
0.73 |
|
Heterogeneity flow index |
|||||
|
Large diameter vessels |
1.0 ± 0.5 |
1.3 ± 1.2 |
1.5 ± 1.4 |
0.07 |
0.02 |
|
Medium diameter vessels |
1.6 ± 1.6 |
1.5 ± 1.4 |
1.7 ± 1.2 |
0.86 |
0.78 |
|
Small diameter vessels |
1.8 ± 1.3 |
1.8 ± 1.2 |
1.7 ± 1.1 |
0.97 |
0.80 |
|
|
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|
ANOVA = analysis of variance. |
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|
Dubin et al. Critical Care 2009 13:R92 doi:10.1186/cc7922 |
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