Figure 4.

Association of serum resistin with severity of disease and survival in critically ill patients. (a) Serum resistin is correlated with Acute Physiology and Chronic Health Evaluation (APACHE) II score (r = 0.481, P = 0.005, Spearman rank correlation test) as a marker of severity of disease only in non-sepsis patients (n = 48, shown), but not in sepsis patients (n = 122, not shown). (b & c) Serum resistin is a prognostic marker in non-sepsis patients. (b) Kaplan-Meier survival curves of non-sepsis patients are displayed, showing that patients with high serum resistin levels (> 10 ng/ml, black) have an increased mortality ain the intensive care unit as compared with patients with low serum resistin (≤ 10 ng/ml, grey). (c) Kaplan-Meier survival curves of non-sepsis patients are displayed, showing that patients with high serum resistin levels (> 10 ng/ml, black) have an unfavorable prognosis with respect to overall survival as compared with patients with low serum resistin (≤ 10 ng/ml, grey). Marks on the survival curves represent the times of censored observation.