Challenging the rationale of routine vasopressor therapy for management of hypotension

doi:10.1186/cc7976

Critical Care

Volume 13
Issue 4

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Commentary

Challenging the rationale of routine vasopressor therapy for management of hypotension

Max Harry Weil and Wanchun Tang

Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA

author email corresponding author email

Critical Care 2009, 13:179doi:10.1186/cc7976


Published:	14 August 2009

See related research by Dubin et al., http://ccforum.com/content/13/3/R92

Abstract

There is persuasive evidence, including the present report by Dubin and colleagues, of a dissociation between increases in arterial pressure produced by vasopressor agents and improvement in microvascular perfusion and delivery of vital substrates. Especially in settings of septic shock, the current routine administration of adrenergic vasopressor therapy therefore may fail to reverse the primary defect.