Table 2 |
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Physiological conditions at the beginning and end of ventilation |
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|
Nonventilated Room air |
VT 6 ml/kg Room air |
VT 30 ml/kg Room air |
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|
|
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|
PH |
7.41 ± 0.04 |
7.36 ± 0.03 |
7.32 ± 0.05 |
|
PaO2 (mm Hg) |
99.1 ± 0.4 |
82.6 ± 7.3 |
86.8 ± 1.2 |
|
PaCO2 (mm Hg) |
40.3 ± 0.4 |
42.1 ± 1.5 |
35.1 ± 1.7 |
|
MAP (mm Hg) |
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|
Start |
87 ± 1.6 |
85.7 ± 2.6 |
84.2 ± 2.1 |
|
End |
85 ± 0.7 |
81.2 ± 1.9 |
73.6 ± 6.3 |
|
PIP, mm Hg |
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|
Start |
9.7 ± 1.3 |
23.8 ± 2.5 |
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|
End |
11.8 ± 1.6 |
28.1 ± 3.4 |
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|
|
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Arterial blood gases and mean arterial pressure of normal nonventilated mice and mice ventilated at a tidal volume of 6 ml/kg or 30 ml/kg for 5 hours (n = 10 per group). VT = tidal volume; MAP = mean arterial pressure; PIP = peak inspiratory pressure. |
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Li et al. Critical Care 2009 13:R108 doi:10.1186/cc7949 |
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