Table 3

Hemodynamic readings taken throughout the four stages of measurement

Stage 1

Stage 2

P_2,1

Stage 3

P_3,1

Stage 4

P_4,1

Responders

SV (ml)

68 ± 25

82 ± 30

0.001

70 ± 26

0.76

86 ± 31

0.004

SV % change from stage 1

21.0 ± 12.5

2.4 ± 7.8

26.3 ± 14.2

CO (L/min)

6.8 ± 2.5

8.0 ± 2.8

0.03

6.9 ± 2.6

0.89

8.3 ± 3.1

0.009

FTc (ms)

363 ± 70

380 ± 68

0.22

356 ± 59

0.62

393 ± 66

0.03

MAP (mmHg)

68 ± 13

72 ± 11

0.11

70 ± 11

0.41

71 ± 16

0.38

Heart rate (beats/min)

101 ± 20

99 ± 21

0.64

100 ± 21

0.81

99 ± 20

0.61

Pulse pressure (mmHg)

42 ± 14

45 ± 14

0.23

45 ± 13

0.30

49 ± 16

0.02

CVP (mmHg)

7.8 ± 4.9

9.9 ± 3.9

0.10

Non-responders

SV (ml)

87 ± 30

91 ± 33

0.58

88 ± 30

0.99

90 ± 31

0.62

SV % change from stage 1

3.2 ± 10.4

0.3 ± 5.9

3.5 ± 8.6

CO (L/min)

8.0 ± 2.9

8.4 ± 3.5

0.46

7.9 ± 2.9

0.97

8.2 ± 3.1

0.71

FTc (ms)

398 ± 66

404 ± 78

0.66

399 ± 68

0.89

405 ± 68

0.58

MAP (mmHg)

74 ± 14

74 ± 16

0.95

73 ± 14

0.72

74 ± 16

0.97

Heart rate (beats/min)

93 ± 20

94 ± 21

0.84

93 ± 20

0.91

92 ± 20

0.75

Pulse pressure (mmHg)

48 ± 15

49 ± 17

0.97

49 ± 18

0.89

49 ± 19

0.83

CVP (mmHg)

8.1 ± 4.8

11.3 ± 5.5

0.01

Except for the comparison of the stage 1 and 4 CVP, the Bonferroni adjusted level of significance for all P values shown is 0.01.

CO = cardiac output; CVP = central venous pressure; FTc = corrected flow time; MAP = mean arterial pressure; SV = stroke volume.

Thiel et al. Critical Care 2009 13:R111   doi:10.1186/cc7955