Diminished human leukocyte antigen-DR expression on circulating monocyte and dendritic cell subsets in sepsis patients. Diminished human leukocyte antigen (HLA)-DR expression on circulating monocyte and dendritic cell subsets in patients with sepsis at baseline and at day 28 compared with healthy controls. Monocyte and dendritic cell subsets were stained and gated as described in Figure 1. (a) The HLA-DR expression in each monocyte subset was quantified using a standardized assay as described in Materials and methods, and is given as HLA-DR antibodies per cell (Ab/cell). (b) For plasmacytoid dendritic cells (PDCs) and myeloid dendritic cells (MDCs), the HLA-DR expression is given as the mean fluorescence intensity (MFI). *P < 0.05, **P < 0.01.
Poehlmann et al. Critical Care 2009 13:R119 doi:10.1186/cc7969