Table 3

Univariate and multivariate logistic analysis for in-hospital mortality

Odds ratio

95% confidence interval

P value


Univariate analysis


Infection source control

0.12

0.02 to 0.89

0.031


ScvO2 optimization

0.30

0.10 to 0.83

0.025


rhAPC

0.18

0.06 to 0.58

0.004


6-hours bundle

0.17

0.06 to 0.50

< 0.001


24-hours bundle

0.19

0.05 to 0.65

0.004


All interventions

0.05

0.01 to 0.31

< 0.005


Team sepsis activation

0.28

0.10 to 0.79

0.015


Multivariate analysis


6-hours bundle

0.15

0.03 to 0.63

0.010


24-hours bundle

0.12

0.02 to 0.52

0.005


Hosmer-Lemeshow test: P = 0.819.

rhAPC = recombinant human activated C protein; ScvO2 = central venous oxygen saturation.

Girardis et al. Critical Care 2009 13:R143   doi:10.1186/cc8029

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