Table 4 |
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Exposures associated with in-hospital mortality in 520 patients with ALI |
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|
Univariable* |
Multivariable* |
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|
|
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|
Exposure |
Odds ratio (95% CI) |
P value |
Odds ratio (95% CI) |
P value |
|
|
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|
Age, years |
1.03 (1.02-1.04) |
<0.0001 |
1.04 (1.02-1.05) |
<0.001 |
|
Ethnicity |
0.98 (0.69-1.4) |
0.93 |
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|
Medical ICU |
2.08 (1.32-3.30) |
0.002 |
2.76(1.42-5.36) |
0.003 |
|
ICU LOS prior to ALI diagnosis |
1.09 (1.01-1.19) |
0.025 |
1.15 (1.03-1.29) |
0.014 |
|
Hospital LOS prior to ALI diagnosis |
1.03 (1.01-1.06) |
0.008 |
1.03 (0.99-1.05) |
0.06 |
|
APACHE II at ICU admission |
1.08 (1.06-1.11) |
<0.0001 |
1.05 (1.02-1.08) |
0.003 |
|
Lung Injury Score at ALI diagnosis |
2.23 (1.77-2.81) |
<0.0001 |
2.33 (1.74-3.12) |
<0.001 |
|
SOFA at ALI diagnosis |
1.26 (1.19-1.33) |
<0.0001 |
1.17 (1.09-1.25) |
<0.001 |
|
PEEP at day 1 after ALI, cmH20 |
1.14 (1.09-1.19) |
<0.0001 |
1.04 (0.98-1.10) |
0.15 |
|
Cumulative fluid balance in first 7 days after ALI diagnosis, Liters |
1.06 (1.04-1.09) |
<0.0001 |
1.06 (1.03-1.09) |
<0.001 |
|
Sepsis vs. non-sepsis ALI risk factor |
2.06 (1.37-3.09) |
0.001 |
1.02 (0.59-1.76) |
0.61 |
|
|
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|
* Calculated using logistic regression analysis. The odds ratio indicates the increased odds of in-hospital mortality for a one unit increase in each continuous exposure variable or for sepsis vs. non-sepsis for this binary exposure variable. ALI = acute lung injury; APACHE = Acute Physiology and Chronic Health Evaluation; CI = confidence interval; ICU = intensive care unit; LOS = length of stay; PEEP = positive end-expiratory pressure; SOFA = Sequential Organ Failure Assessment. |
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|
Sevransky et al. Critical Care 2009 13:R150 doi:10.1186/cc8048 |
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