Table 5

Correlation between MMP-9, MMP-10, and TIMP-1 with TNF-α and IL-10 serum levels

TNF-α (pg/ml)

IL-10 (pg/ml)

TNF-α/IL-10 ratio

MMP-9: ng/ml

rho = -0.25

rho = -0.38

rho = 0.33

p = 0.001

p < 0.001

p < 0.001

TIMP-1: ng/ml

rho = 0.56

rho = 0.50

rho = -0.26

p < 0.001

p < 0.001

p = 0.001

MMP-10: pg/ml

rho = 0.35

rho = 0.30

rho = -0.16

p < 0.001

p < 0.001

p = 0.04

SOFA = Sepsis-related Organ Failure Assessment score; aPTT = Activated partial thromboplastin time; INR = International normalized ratio; MMP = Matrix metalloproteinase; TIMP = Iissue inhibitor of matrix metalloproteinase; IL = interleukin; rho = Spearman's rank correlation coefficient.

Lorente et al. Critical Care 2009 13:R158   doi:10.1186/cc8115