Table 3

Results of Cox proportional hazards regression analysis

Variable†

Hazard ratio

95% CI

P value

Received EGDT*

0.55

0.35-0.87

0.01

Lowest ED SBP

1.0

0.99-1.01

0.59

Highest ED RR

1.0

0.99-1.01

0.55

DD-ESRD**

1.5

0.95-2.3

0.08

Initial SOFA score

1.1

1.05-1.2

0.004

Received steroids***

1.1

0.7-1.7

0.70

CI = confidence interval; DD ESRD = dialysis dependent end stage renal disease; ED = emergency department; EGDT - early goal directed therapy; RR = respiratory rate; SBP = systolic blood pressure; SOFA = sequential organ failure assessment.

* Patients in the pre-implementation group did not receive EGDT and those in the post-implementation group did receive EGDT.

** Refers to patient reported diagnosis established previous to index hospitalization.

*** Refers to patients who received systemic corticosteroids during the index hospitalization.

^† Dependent variable: one-year mortality.

Model Analysis

Log likelihood with all covariates = -613.

Deviance chi-squared = 26.9, degrees of freedom = 6, P = 0.0001.

Puskarich et al. Critical Care 2009 13:R167   doi:10.1186/cc8138