Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study

Russel J Roberts¹ , Jeffrey F Barletta² , Jeffrey J Fong³ , Greg Schumaker⁴ , Philip J Kuper⁵ , Stella Papadopoulos⁶ , Dinesh Yogaratnam⁷ , Elise Kendall⁸ , Renee Xamplas⁹ , Anthony T Gerlach¹⁰ , Paul M Szumita¹¹ , Kevin E Anger¹¹ , Paul A Arpino¹² , Stacey A Voils¹³ , Philip Grgurich⁶ , Robin Ruthazer¹⁴ and John W Devlin¹⁵

¹Department of Pharmacy, Tufts Medical Center, 800 Washington Street, mailstop #420, Boston, MA 02111, USA

²Department of Pharmacy, Spectrum Health, 100 Michigan Street NE (MC01), Grand Rapids, MI 49503, USA

³Department of Pharmacy Practice, Massachusetts College of Pharmacy and Health Sciences, 19 Foster Street, Worcester, MA 01608, USA

⁴Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA

⁵Department of Pharmacy, Mayo Clinic College of Medicine, Mayo School of Health Sciences, Siebens Medical Education Building 11200 First Street SW, Rochester, MN 55905, USA

⁶Department of Pharmacy, Boston Medical Center, 1 Boston Medical Center Place, Boston, MA 02118, USA

⁷Department of Pharmacy, University of Massachusetts Memorial Medical Center, 119, Belmont Street, Worcester, MA 01605, USA

⁸Department of Pharmacy, Concord Regional Hospital, 250 Pleasant Street, Concord, NH 03301, USA

⁹Department of Pharmacy Practice, John H. Stroger Jr. Hospital of Cook County, 1901 W. Harrison Street, Chicago, IL 60612, USA

¹⁰Department of Pharmacy and Center for Critical Care, The Ohio State University Medical Center, 410 West 10thAvenue, Columbus, OH 43210, USA

¹¹Department of Pharmacy Services, Brigham and Women's Hospital, Pharmacy Administration L-2, 75 Francis Street, Boston, MA 02115, USA

¹²Department of Pharmacy, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA

¹³Stacey Voils, Department of Pharmacy, Virginia Commonwealth University Health System, 410 North 12thStreet, Richmond, VA 23298, USA

¹⁴Institute for Clinical Research and Health Policy Studies, Biostatics Research Center, Tufts Medical Center, 35 Kneeland Street, Boston, MA 02111, USA

¹⁵Northeastern University School of Pharmacy, 360 Huntington Avenue, Mugar 206, Boston, MA 02115, USA