Table 1 |
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|
Comparison of demographic variables and clinical outcomes between PRIS and non-PRIS patients |
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|
PRIS n = 11 |
No PRIS n = 1006 |
P value |
|
|
|
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|
Age (years)A |
58 ± 14 |
56 ± 18 |
0.64 |
|
|
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|
Male (%) |
82 |
65 |
0.4 |
|
|
|||
|
APACHE II scoreA |
25 ± 6 |
20 ± 6 |
0.03 |
|
|
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|
Admitting service (%) |
|||
|
|
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|
Medicine |
36 |
35 |
0.82 |
|
|
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|
Surgery |
|||
|
|
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|
Neurosurgery |
9 |
25 |
0.39 |
|
|
|||
|
Trauma |
9 |
23 |
0.47 |
|
|
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|
Other surgery |
46 |
17 |
0.04 |
|
|
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|
Primary reason for ICU admit (%) |
|||
|
|
|||
|
Trauma |
18 |
23 |
1.0 |
|
|
|||
|
Surgery |
28 |
21 |
0.89 |
|
|
|||
|
Neurological |
9 |
20 |
0.6 |
|
|
|||
|
Respiratory failure |
36 |
17 |
0.2 |
|
|
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|
Cardiac |
0 |
9 |
0.61 |
|
|
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|
Other |
9 |
10 |
0.77 |
|
|
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|
Past medical history (%) |
|||
|
|
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|
Coronary artery disease |
27 |
30 |
0.89 |
|
|
|||
|
Malignancy |
36 |
18 |
0.24 |
|
|
|||
|
Congestive heart failure |
18 |
18 |
0.71 |
|
|
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|
Diabetes |
18 |
16 |
0.83 |
|
|
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|
Chronic obstructive pulmonary disease |
27 |
10 |
0.12 |
|
|
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|
Other |
9 |
12 |
0.87 |
|
|
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|
Use of propofol dose >83 μg/kg/min (%) |
18 |
10 |
0.68 |
|
|
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|
Duration of propofol (days)B |
5 (3-7) |
4 (3-7) |
0.43 |
|
|
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|
Number of PRIS clinical manifestationsC |
5 (2-7) |
1 (0-6) |
0.0001 |
|
|
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|
Duration of ICU stay (days)B |
14 (10-18) |
12 (7-20) |
0.4 |
|
|
|||
|
ICU mortality (%) |
18 |
20 |
0.82 |
|
|
|||
|
Hospital mortality (%) |
18 |
21 |
0.88 |
|
|
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|
APACHE = acute physiology and chronic health evaluation; ICU = intensive care unit; PRIS = propofol-relation infusion syndrome. AMean ± standard deviation BMedian (interquartile range) CMedian (Range) |
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|
Roberts et al. Critical Care 2009 13:R169 doi:10.1186/cc8145 |
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