Figure 3.

Apoptosis of CD14-monocytes and of CD4-lymphocytes of healthy volunteers. Induction of apoptosis of CD14-monocytes and inhibition of apoptosis of CD4-lymphocytes of healthy volunteers according to four different patterns of stimulation by isolates of Acinetobacter baumannii and of Pseudomonas aeruginosa. A = un-stimulated controls; B = three-step stimulation mimicking pathogenesis of ventilator-associated pneumonia (VAP); C = abrupt stimulation with pathogens of VAP; and D = abrupt stimulation mimicking pathogenesis of bacteremia. Asterisks denote significant difference between patterns B and D and between patterns B and A. SE = standard error.