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Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion

Mitchell J Cohen*, Karim Brohi, Carolyn S Calfee, Pamela Rahn, Brian B Chesebro, Sarah C Christiaans, Michel Carles, Marybeth Howard and Jean-François Pittet

Critical Care 2009, 13:R174 doi:10.1186/cc8152

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