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Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial

Martin W Dünser1*, Esko Ruokonen2, Ville Pettilä3, Hanno Ulmer4, Christian Torgersen5, Christian A Schmittinger5, Stephan Jakob1 and Jukka Takala1

Author Affiliations

1 Department of Intensive Care Medicine, Inselspital, Freiburgstrasse, 3010 Bern, Switzerland

2 Department of Intensive Care, Kuopio University Hospital and Kuopio University, 70211 Kuopio, Finland

3 Australian and New Zealand Intensive Care Research Centre, Department of EPM, Monash University, 89 Commercial Road, Melbourne 3004, Victoria, Australia

4 Department of Medical Statistics, Informatics and Health Economics, Innsbruck Medical University, Schöpfstrasse, 6020 Innsbruck, Austria

5 Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria

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Critical Care 2009, 13:R181 doi:10.1186/cc8167


See related commentary by Jones et al., http://ccforum.com/content/14/1/102

Published: 16 November 2009

Additional files

Additional file 1:

A Word file containing three tables and one figure. Table S1 is a table that lists the characteristics of the 68 excluded patients. Table S2 is a table that lists the disease-related events and vasopressor support during the shock period in the 68 excluded patients. Table S3 is a table that lists the association between heart rate during septic shock and 28-day mortality. The figure presents the vasopressor load in study patients with a mean arterial blood pressure (MAP) of less than 70 mmHg during the shock period (n = 68; mean vasopressor load 2.31 ± 6.56 μg/kg/min) compared with the mean vasopressor load in study patients with a MAP of more than 70 mmHg during the shock period (n = 290; mean vasopressor load 0.64 ± 1.92 μg/kg/min, reference line).

Format: DOC Size: 47KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 2:

A Word file containing three tables. Table S1 is a table that lists the characteristics of the study population. Table S2 is a table that lists disease-related events and vasopressor support during the shock period. Table S3 is a table that lists the adjusted logistic regression model to evaluate the association between mean arterial blood pressure (MAP), mean vasopressor load and 28-day mortality.

Format: DOC Size: 40KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data