Table 5 |
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|
Clinical relevance of Interleukin-10 haplotypes in major trauma patients |
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|
Haplotype* |
Count |
IL-10 (pg/ml) |
MODS |
Sepsis (%) |
|
|
||||
|
0(ATA) |
71 |
72.18 ± 22.51 |
4.25 ± 2.60 |
28 (39.4) |
|
1(ATA) |
157 |
65.19 ± 20.36 |
5.00 ± 2.89 |
76 (48.4) |
|
2(ATA) |
79 |
60.27 ± 19.24a, c |
4.24 ± 2.39 |
43 (54.4) |
|
|
||||
|
*'0 ATA haplotype' includes the following genotypes: ATC/ATC, ATC/ACC, ACA/ACA, ACA/ACC, ACC/ACC, ATC/GTC, ATC/GCC, ACC/GTC, ACA/GCA, ACC/GCA, ACA/GCC, ACC/GCC, GTA/GTC, GTC/GTC, GTA/GCC and GTC/GCA; '1 ATA haplotype' includes ATA/ATC, ATA/ACA, ATA/ACC, ATA/GTA, ATA/GTC, ATA/GCA and ATA/GCC; '2 ATA haplotype' is ATA/ATA. haplotype is indicated in an order of -1082A, -819T and -592A. a: 2 ATA vs 0 ATA, P = 0.041; c: haplotype dose effect, P = 0.041. MODS = multiple-organ dysfunction syndrome. |
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|
Zeng et al. Critical Care 2009 13:R188 doi:10.1186/cc8182 |
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