Research
Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
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* Corresponding author: Jesus F Bermejo-Martin jfbermejo@saludcastillayleon.es
1 National Centre of Influenza, Hospital Clínico Universitario de Valladolid, Avda Ramón y Cajal 3, Valladolid, 47005, Spain
2 Unidad de Investigación en Infección e Inmunidad- Microbiology Service,. Hospital Clínico Universitario de Valladolid- IECSCYL, Avda Ramón y Cajal 3, Valladolid, 47005, Spain
3 Virology Laboratory, Hospital Clinic de Barcelona, Carrer de Casanova 143, Barcelona, 08036, Spain
4 Critical Care Department, Joan XXIII University Hospital-CIBERes Enfermedades Respiratorias-IISPV. Mallafre Guasch 4, Tarragona, 43007, Spain
5 Critical Care Department, Hospital Universitario La Fe, Avda Campanar 21, Valencia, 46009, Spain
6 Microbiology Service, Hospital Son Llatzer, Ctra. Manacor, km 4, Palma de Mallorca 07198, Spain
7 Intensive Care Unit, Hospital General San Jorge, Avenida Martínez De Velasco 36, Huesca, 22004ý, Spain
8 Intensive Care Unit & Internal Medicine Service, Hospital Gregorio Marañón, C/Doctor Esquerdo 46, Madrid, 28007, Spain
9 Microbiology Service, Hospital Universitario de Canarias, Carretera Del Rosario 145, Santa Cruz De Tenerifeý, 38009, Spain
10 Microbiology Service, Hospital General de La Palma, Buenavista de Arriba, s/n, Breña Alta, 38713, Spain
11 Intensive Care Unit, Hospital Universitario de Canarias, Carretera Del Rosario 145, Santa Cruz De Tenerifeý, 38009, Spain
12 Intensive Care Unit, Hospital Virgen del Rocío, Avenida Manuel Siurot s/n, Sevilla, 41013, Spain
13 Intensive Care Unit Service, Hospital Son Llatzer, Ctra. Manacor, km 4, Palma de Mallorca, 07198, Spain
14 Intensive Care Unit Service, Hospital Lozano Blesa, Avenida San Juan Bosco 15, Zaragozaý,50009, Spain
15 Microbiology Service, Hospital Universitario Ramón y Cajal & CIBERESP, Carretera Colmenar Viejo KM 9,100, Madrid, 28049, Spain
16 Intensive Care Unit, Hospital Universitario Ramón y Cajal, Carretera Colmenar Viejo KM 9,100, Madrid, 28049, Spain
17 Infectious Diseases Service, Hospital Clínico Universitario, Avda Ramón y Cajal 3, Valladolid, 47005, Spain
18 Preventive Medicine Service, Hospital Universitario Valle Hebron & CIBERESP, Paseo Vall d'Hebron, 119-129, Barcelona, 08035, Spain
19 Experimental Theraputics Division, University Health Network, Medical Discovery Tower, 3rd floor Room 913-916,101 Collegue Street, Toronto, ON M5G 1L7, Canada
20 International Institute of Infection and Immunity, Shantou University, 22 Xinling Road, Shantou, Guangdong Province, 515031, PR China
21 Intensive Care Unit, Hospital de Villarobredo, Avenida Miguel de Cervantes s/n, Villarrobledo, 02600, Spain
22 Department of Immunology, University of Toronto, Medical Discovery Tower, 3rd floor Room 913-916,101 Collegue Street, Toronto, ON M5G 1L7, Canada
Critical Care 2009, 13:R201 doi:10.1186/cc8208
See related commentary by Fernández de Castro et al., http://ccforum.com/content/14/1/115, related letter by Krstíc, http://ccforum.com/content/14/2/410, related letter by Kawashima et al., http://ccforum.com/content/14/2/411 and related letter by Krystíc, http://ccforum.com/content/14/3/417
Published: 11 December 2009Additional files
Additional file 1:
Table listing the immune mediators' profiles in serum during the early response against the nvH1N1 virus.
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