Early acute kidney injury in Northern Ireland ICUs

doi:10.1186/cc7427

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Introduction
Methods
Results
Conclusion
References

Critical Care
Volume 13
Suppl 1

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Borthwick E
Harris S
Welch C
Maxwell A
McAuley DF
Glover P
Harrison D
Rowan K

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Harris S
Welch C
Maxwell A
McAuley DF
Glover P
Harrison D
Rowan K
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This article is part of the supplement: 29th International Symposium on Intensive Care and Emergency Medicine .

Poster presentation

Early acute kidney injury in Northern Ireland ICUs

E Borthwick¹, S Harris², C Welch³, A Maxwell¹, DF McAuley⁴, P Glover⁴, D Harrison³ and K Rowan³

¹Regional Nephrology Unit, Belfast, UK

²UCL, London, UK

³Intensive Care National Audit and Research Centre, London, UK

⁴Royal Victoria Hospital, Belfast, UK

from 29th International Symposium on Intensive Care and Emergency Medicine
Brussels, Belgium. 24–27 March 2009

Critical Care 2009, 13(Suppl 1):P263doi:10.1186/cc7427

The electronic version of this abstract is the complete one and can be found online at: http://ccforum.com/content/13/S1/P263

Published:

13 March 2009

Introduction

There are limited data about the epidemiology of acute kidney injury (AKI) in critically ill patients in Northern Ireland. The aim of this study was to examine AKI within 24 hours of ICU admission and its relation to outcomes (ICU mortality and hospital mortality).

Methods

A secondary analysis of prospectively collected data in the Intensive Care National Audit and Research Centre Case Mix Programme Database. The Case Mix Programme Database was interrogated and data extracted from 22,313 admissions to eight ICUs from 1999 to 2007. The presence of AKI was assessed within the first 24 hours after admission (early AKI) and classified according to the RIFLE criteria. Trends over time were described for the RIFLE categories, and outcomes of admissions in each category were summarised. Where available, information on the use of renal replacement therapy during the ICU stay was analysed.

Results

Trends in early AKI changed little over time: 35.5% of patients sustained AKI (risk 13.5%, injury 11.1%, failure 9.8%, end-stage 1.2%) and 9% of patients received renal replacement therapy. Outcomes are presented in Table 1.

Table 1. Outcomes

Conclusion

For the first time we have established the incidence of early AKI using the RIFLE criteria in Northern Ireland ICUs. This will inform renal service development in ICUs. The incidence of severe AKI is high relative to the rest of the UK [1] although it is low compared with the US [2]. Mortality increases with severity of renal injury.

References

Kolhe , et al.:
Crit Care. 2008, 12(Suppl 1):S2. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text
Hoste , et al.:
Crit Care. 2006, 10:R73. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text

This article is part of the supplement: 29th International Symposium on Intensive Care and Emergency Medicine .

Early acute kidney injury in Northern Ireland ICUs

Introduction

Methods

Results

Conclusion

References

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