Critical Care

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Sepsis biomarkers: a review

Charalampos Pierrakos and Jean-Louis Vincent*

Critical Care 2010, 14:R15 doi:10.1186/cc8872

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Original research   Open Access

High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

Sisse R Ostrowski, Anne Marie Sørensen, Nis A Windeløv, Anders Perner, Karen-Lise Welling, Michael Wanscher, Claus F Larsen, Pär I Johansson Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2012, 20:27 (10 April 2012)

Commentary   Subscription Highly Accessed

Lest we forget the endothelial glycocalyx in sepsis

Anne Burke-Gaffney, Timothy W Evans Critical Care 2012, 16:121 (30 March 2012)

Research   Open Access Highly Accessed

Clinical utility of biomarkers of endothelial activation in sepsis-a systematic review

Katharine Xing, Srinivas Murthy, W Conrad Liles, Jeffrey M Singh Critical Care 2012, 16:R7 (16 January 2012)

Minireview   Open Access Highly Accessed

suPAR as a prognostic biomarker in sepsis

Katia Donadello, Sabino Scolletta, Cecilia Covajes, Jean-Louis Vincent BMC Medicine 2012, 10:2 (5 January 2012)

This article is part of a collection on Clinical biomarkers

Donadello and colleagues review the clinical utility of suPAR as a biomarker for sepsis, and discuss how it can be used to monitor response to treatment in critically ill patients.

Research article   Open Access Highly Accessed

Detrimental effect of apoptosis of lymphocytes at an early time point of experimental abdominal sepsis

Stefanos Atmatzidis, Ioannis M Koutelidakis, Grigorios Chatzimavroudis, Antigone Kotsaki, Konstantinos Louis, Aikaterini Pistiki, Athina Savva, Anastasia Antonopoulou, Konstantinos Atmatzidis, Evangelos J Giamarellos-Bourboulis BMC Infectious Diseases 2011, 11:321 (20 November 2011)

Research   Open Access

Early natural killer cell counts in blood predict mortality in severe sepsis

David Andaluz-Ojeda, Verónica Iglesias, Felipe Bobillo, Raquel Almansa, Lucía Rico, Francisco Gandía, Ana Ma Loma, Concepción Nieto, Rosa Diego, Epifanio Ramos, Mercedes Nocito, Salvador Resino, Jose M Eiros, Eduardo Tamayo, Raul de Lejarazu, Jesús F Bermejo-Martin Critical Care 2011, 15:R243 (21 October 2011)

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C-reactive protein, an early marker of community-acquired sepsis resolution: a multi-center prospective observational study

Pedro Póvoa, Armando M Teixeira-Pinto, António H Carneiro, Critical Care 2011, 15:R169 (15 July 2011)

Levels of C-reactive protein during the first five days in the intensive care unit were predictive of patient outcome in patients with community-acquired sepsis being treated with antibiotics.

Review   Subscription Highly Accessed

Clinical review: Fever in septic ICU patients - friend or foe?

Yoann Launey, Nicolas Nesseler, Yannick Mallédant, Philippe Seguin Critical Care 2011, 15:222 (7 June 2011)

Research   Open Access Highly Accessed

Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit

Maryam Nejat, John W Pickering, Robert J Walker, Justin Westhuyzen, Geoffrey M Shaw, Christopher M Frampton, Zoltán H Endre Critical Care 2010, 14:R85 (12 May 2010)