Table 5 |
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|
Prediction of unfavourable outcome using the optimal cutoffs of the ADC and the percent ADC |
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|
Grey matter structures |
Optimal cutoff |
Sensitivity with 95% CI |
Specificity with 95% CI |
PPV with 95% CI |
NPV with 95% CI |
|
|
|
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|
ADC |
Percent ADC** |
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|
|
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|
Frontal cortex |
0.685 |
79 |
73% (45 to 85%) |
100% (56 to 100%) |
100% (68 to 100%) |
64% (32 to 88%) |
|
Parietal cortex* |
0.674 |
77 |
87% (58 to 98%) |
100% (56 to 100%) |
100% (72 to 100%) |
78% (40 to 96%) |
|
Temporal cortex |
0.640 |
69 |
67% (39 to 87%) |
100% (56 to 100%) |
100% (66 to 100%) |
58% (29 to 84%) |
|
Occipital cortex* |
0.740 |
82 |
93% (66 to 100%) |
100% (56 to 100%) |
100% (73 to 100%) |
88% (47 to 99%) |
|
Precentral cortex* |
0.606 |
84 |
87% (58 to 98%) |
100% (56 to 100%) |
100% (72 to 100%) |
78% (40 to 96%) |
|
Postcentral cortex |
0.625 |
86 |
73% (45 to 91%) |
100% (56 to 100%) |
100% (68 to 100%) |
64% (32 to 88%) |
|
Caudate nucleus |
0.621 |
76 |
67% (39 to 87%) |
100% (56 to 100%) |
100% (66 to 100%) |
58% (29 to 84%) |
|
Putamen* |
0.590 |
75 |
93% (66 to 100%) |
100% (56 to 100%) |
100% (73 to 100%) |
88% (47 to 99%) |
|
Thalamus* |
0.647 |
85 |
87% (58 to 98%) |
100% (56 to 100%) |
100% (72 to 100%) |
78% (40 to 96%) |
|
|
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|
ADC unit × 10-3 mm2/sec; PPV, positive predictive value; NPV, negative predictive value Optimal cutoff values predicting unfavourable outcome were determined by ROC curve analysis in patients and controls. *Area under the ROC curve was greater than 0.9 with a P value less than 0.001. **Percent ADC expressed the (absolute ADC value/mean normal control ADC value) × 100. |
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|
Choi et al. Critical Care 2010 14:R17 doi:10.1186/cc8874 |
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