Critical Care

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Quality of life in patients aged 80 or over after ICU discharge

Alexis Tabah1, Francois Philippart1,2, Jean F Timsit3,4, Vincent Willems1, Adrien Français3, Alain Leplège5, Jean Carlet1, Cédric Bruel1, Benoit Misset1,6 and Maité Garrouste-Orgeas1,2*

Author Affiliations

1 Medical-Surgical ICU, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014 Paris, France

2 Cytokines and inflammation unit, Institut Pasteur, 28 rue du Docteur Roux, 75015 Paris, France

3 INSERM U823 "Epidemiology of cancers and severe diseases", Albert Bonniot Institute, Rond-point de la Chantourne, 38706 La Tronche Cedex

4 Medical Intensive Care Unit, Albert Michallon Teaching Hospital, Joseph Fournier University, BP 217, 38043 Grenoble cedex 09, France

5 Recherche épistémologiques et historiques sur les sciences exactes et les institutions scientifiques (REHSEIS), UMR 7596, Université Paris Diderot, Paris VII, 5 rue Thomas Mann, 75205 Paris Cedex 13, France

6 University Paris Descartes, 12 rue de l'école de médecine, 75005 Paris, France

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Critical Care 2010, 14:R2 doi:10.1186/cc8231


See related letter by Koeze and Zijlstra, http://ccforum.com/content/14/4/434

Published: 8 January 2010

Abstract

Introduction

Our objective was to describe self-sufficiency and quality of life one year after intensive care unit (ICU) discharge of patients aged 80 years or over.

Methods

We performed a prospective observational study in a medical-surgical ICU in a tertiary non-university hospital. We included patients aged 80 or over at ICU admission in 2005 or 2006 and we recorded age, admission diagnosis, intensity of care, and severity of acute and chronic illnesses, as well as ICU, hospital, and one-year mortality rates. Self-sufficiency (Katz Index of Activities of Daily Living) was assessed at ICU admission and one year after ICU discharge. Quality of life (WHO-QOL OLD and WHO-QOL BREF) was assessed one year after ICU discharge.

Results

Of the 115 consecutive patients aged 80 or over (18.2% of admitted patients), 106 were included. Mean age was 84 ± 3 years (range, 80 to 92). Mortality was 40/106 (37%) at ICU discharge, 48/106 (45.2%) at hospital discharge, and 73/106 (68.9%) one year after ICU discharge. In the 23 patients evaluated after one year, self-sufficiency was unchanged compared to the pre-admission status. Quality of life evaluations after one year showed that physical health, sensory abilities, self-sufficiency, and social participation had slightly worse ratings than the other domains, whereas social relationships, environment, and fear of death and dying had the best ratings. Compared to an age- and sex-matched sample of the general population, our cohort had better ratings for psychological health, social relationships, and environment, less fear of death and dying, better expectations about past, present, and future activities and better intimacy (friendship and love).

Conclusions

Among patients aged 80 or over who were selected at ICU admission, 80% were self-sufficient for activities of daily living one year after ICU discharge, 31% were alive, with no change in self-sufficiency and with similar quality of life to that of the general population matched on age and sex. However, these results must be interpreted cautiously due to the small sample of survivors.