Figure 8.

Effect of resin adsorption on albumin internalization and expression of megalin by TEC. Representative FACS and confocal microscopy analysis of FITC-albumin uptake (green fluorescence) and megalin expression (red fluorescence) in tubular epithelial cells (TEC) incubated with control healthy plasma or septic plasma before and after (Septic + CG161 M) Amberchrom resin adsorption. For FACS analysis, Kolomogorov Smirnov statistical analysis was performed. In merge images, nuclei were counterstained by 0.5 μg/ml Hoechst.