Critical Care | Volume 14 Issue 2

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	Volume 14 Issue 2
	Comment
	Commentary Patients with diabetes in the intensive care unit; not served by treatment, yet protected? Sarah E Siegelaar, J Hans Devries, Joost B Hoekstra Critical Care 2010, 14:126 (1 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Novel representation of physiologic states during critical illness and recovery Timothy G Buchman Critical Care 2010, 14:127 (4 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Pitfalls in haemodynamic monitoring based on the arterial pressure waveform Luigi Camporota, Richard Beale Critical Care 2010, 14:124 (5 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Goal-directed or goal-misdirected - how should we interpret the literature? Anthony M Roche, Timothy E Miller Critical Care 2010, 14:129 (10 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Fish oil-containing lipid emulsions in patients with sepsis Konstantin Mayer, Werner Seeger Critical Care 2010, 14:128 (10 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Critical care in the developing world - a challenge for us all Charles D Gomersall Critical Care 2010, 14:131 (11 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary New versus old blood - the debate continues John Laurie, Duncan Wyncoll, Claire Harrison Critical Care 2010, 14:130 (12 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The kinetics of T regulatory cells in shock: beyond sepsis Eirini Christaki, Eleni Patrozou Critical Care 2010, 14:132 (19 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Can heterogeneity in ventilation be good? Eduardo LV Costa, Marcelo BP Amato Critical Care 2010, 14:134 (22 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Disaster medicine: the caring contradiction David Crippen, Charles Krin, Dean Lorich, Ken Mattox Critical Care 2010, 14:133 (22 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Cardiac arrest - has the time of MRI come? Damien Galanaud, Louis Puybasset Critical Care 2010, 14:135 (26 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Where does the lactate come from? A rare cause of reversible inhibition of mitochondrial respiration Bruno Levy, Pierre Perez, Jessica Perny Critical Care 2010, 14:136 (1 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Does anesthetic provide similar neuroprotection to therapeutic hypothermia after cardiac arrest? Hong Zhang Critical Care 2010, 14:137 (8 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Leptin in sepsis: a well-suited biomarker in critically ill patients? Rodolfo Bracho-Riquelme, Miguel Reyes-Romero Critical Care 2010, 14:138 (9 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Clinical features of H1N1 2009 infection in critically ill immunocompromised patients Laurent Camous, Virginie Lemiale, Emmanuel Canet, Adeline Max, David Schnell, Jerome Le Goff, Antoine Rabbat, Benoit Schlemmer, Élie Azoulay Critical Care 2010, 14:139 (14 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Wet lungs, broken hearts and difficult therapies after subarachnoid hemorrhage Nino Stocchetti Critical Care 2010, 14:140 (16 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Statins for acutely hospitalized patients: randomized controlled trials are long overdue Gordon R Bernard Critical Care 2010, 14:141 (19 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Adequate thromboprophylaxis in critically ill patients Marcel Levi Critical Care 2010, 14:142 (21 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary A novel effect of eicosapentaenoic acid: improved diaphragm strength in endotoxemia Philip C Calder Critical Care 2010, 14:143 (23 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Inhaled activated protein C: a new therapy for the prevention of ventilator-induced lung injury? Edward Abraham Critical Care 2010, 14:144 (29 April 2010) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Choosing patient-tailored hemodynamic monitoring Cornelis Slagt, Rose-Marieke BGE Breukers, AB Johan Groeneveld Critical Care 2010, 14:208 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Role of CD14 in lung inflammation and infection Adam Anas, Tom Poll, Alex F de Vos Critical Care 2010, 14:209 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review New and conventional strategies for lung recruitment in acute respiratory distress syndrome Paolo Pelosi, Marcelo de Abreu, Patricia RM Rocco Critical Care 2010, 14:210 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Weaning failure of cardiac origin: recent advances Jean-Louis Teboul, Xavier Monnet, Christian Richard Critical Care 2010, 14:211 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Prevention of central venous catheter-related infection in the intensive care unit Denis Frasca, Claire Dahyot-Fizelier, Olivier Mimoz Critical Care 2010, 14:212 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Venous oxygen saturation as a physiologic transfusion trigger Benoit Vallet, Emmanuel Robin, Gilles Lebuffe Critical Care 2010, 14:213 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Renal dysfunction in chronic liver disease Andy Slack, Andrew Yeoman, Julia Wendon Critical Care 2010, 14:214 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Cerebral perfusion in sepsis Christoph S Burkhart, Martin Siegemund, Luzius A Steiner Critical Care 2010, 14:215 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Laparostomy: why and when? Ari K Leppäniemi Critical Care 2010, 14:216 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Patient safety and acute care medicine: lessons for the future, insights from the past Peter G Brindley Critical Care 2010, 14:217 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
	Review Clinical review: Scoring systems in the critically ill Jean-Louis Vincent, Rui Moreno Critical Care 2010, 14:207 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Vaccine protection strategies during pandemic flu outbreaks Joel V Chua, Wilbur H Chen Critical Care 2010, 14:218 (16 April 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Bacterial pneumonia with influenza - pathogenesis and clinical implications Koenraad F van der Sluijs, Tom van der Poll, René Lutter, Nicole P Juffermans, Marcus J Schultz Critical Care 2010, 14:219 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Review Clinical review: Practical recommendations on the management of perioperative heart failure in cardiac surgery Alexandre Mebazaa, Antonis A Pitsis, Alain Rudiger, Wolfgang Toller, Dan Longrois, Sven-Erik Ricksten, Ilona Bobek, Stefan De Hert, Georg Wieselthaler, Uwe Schirmer, Ludwig K von Segesser, Michael Sander, Don Poldermans, Marco Ranucci, Peter CJ Karpati, Patrick Wouters, Manfred Seeberger, Edith R Schmid, Walter Weder, Ferenc Follath Critical Care 2010, 14:201 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Carbon dioxide Gerard Curley, John G Laffey, Brian P Kavanagh Critical Care 2010, 14:220 (30 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: What is the role for autopsy in the ICU? Greet De Vlieger, Elien Mahieu, Wouter Meersseman Critical Care 2010, 14:221 (28 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Report
	Journal club critique The role of noninvasive ventilation in acute cardiogenic pulmonary edema Ashar Salman, Eric B Milbrandt, Michael R Pinsky Critical Care 2010, 14:303 (12 March 2010) Full text \| PDF \| PubMed
	Journal club critique Thrombolysis during out-of-hospital cardiac arrest: a lesson in the law of diminishing returns James M Dargin, Lillian L Emlet Critical Care 2010, 14:304 (22 March 2010) Full text \| PDF \| PubMed
	Journal club critique Intensivists: don't quit your day job...yet! Gregory A Watson, Louis H Alarcon Critical Care 2010, 14:305 (7 April 2010) Full text \| PDF \| PubMed
	Journal club critique Is albumin use SAFE in patients with traumatic brain injury? Christopher R Brackney, Luis A Diaz, Eric B Milbrandt, Ali Al-Khafaji, Joseph M Darby Critical Care 2010, 14:307 (9 April 2010) Full text \| PDF \| PubMed
	Journal club critique Ave, CESAR, morituri te salutant! (Hail, CESAR, those who are about to die salute you!) David J Wallace, Eric B Milbrandt, Arthur Boujoukos Critical Care 2010, 14:308 (26 April 2010) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Book report Cardiopulmonary Bypass Luc Rondelez, Philippe Linden Critical Care 2010, 14:306 (18 March 2010) Full text \| PDF \| PubMed
	Research
	Research Prolonged mechanical ventilation in a respiratory-care setting: a comparison of outcome between tracheostomized and translaryngeal intubated patients Yao-Kuang Wu, Ying-Huang Tsai, Chou-Chin Lan, Chun-Yao Huang, Chih-Hsin Lee, Kuo-Chin Kao, Jui-Ying Fu Critical Care 2010, 14:R26 (1 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Although the type of mechanical ventilation used doesn’t appear to increase successful weaning, patients who are tracheostomized as opposed to translaryngeal intubated are significantly more likely to survive.
	Research Gram-negative bacteremia induces greater magnitude of inflammatory response than Gram-positive bacteremia Ryuzo Abe, Shigeto Oda, Tomohito Sadahiro, Masataka Nakamura, Yo Hirayama, Yoshihisa Tateishi, Koichiro Shinozaki, Hiroyuki Hirasawa Critical Care 2010, 14:R27 (4 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study Thomas Benfield, Karen Ejrnæs, Klaus Juul, Christian Østergaard, Jannik Helweg-Larsen, Nina Weis, Lea Munthe-Fog, Gitte Kronborg, Marianne Andersen, Anne Tybjærg-Hansen, Børge G Nordestgaard, Peter Garred Critical Care 2010, 14:R28 (5 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Preadmission statin use and one-year mortality among patients in intensive care - A cohort study Steffen Christensen, Reimar W Thomsen, Martin B Johansen, Lars Pedersen, Reinhold Jensen, Kim M Larsen, Anders Larsson, Else Tønnesen, Henrik Sørensen Critical Care 2010, 14:R29 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Intensive care unit-acquired infection as a side effect of sedation Saad Nseir, Demosthenes Makris, Daniel Mathieu, Alain Durocher, Charles-Hugo Marquette Critical Care 2010, 14:R30 (15 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Ischemia as a possible effect of increased intra-abdominal pressure on central nervous system cytokines, lactate and perfusion pressures Athanasios Marinis, Eriphili Argyra, Pavlos Lykoudis, Paraskevas Brestas, Kassiani Theodoraki, Georgios Polymeneas, Efstathios Boviatsis, Dionysios Voros Critical Care 2010, 14:R31 (15 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Infections of respiratory or abdominal origin in ICU patients: what are the differences? Elena Volakli, Claudia Spies, Argyris Michalopoulos, AB Johan Groeneveld, Yasser Sakr, Jean-Louis Vincent Critical Care 2010, 14:R32 (15 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research The diagnostic value of serum leptin monitoring and its correlation with tumor necrosis factor-α in critically ill patients: a prospective observational study Ayman Yousef, Yasser Amr, Ghada Suliman Critical Care 2010, 14:R33 (15 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury Marcelo Gama de Abreu, Maximiliano Cuevas, Peter M Spieth, Alysson R Carvalho, Volker Hietschold, Christian Stroszczynski, Bärbel Wiedemann, Thea Koch, Paolo Pelosi, Edmund Koch Critical Care 2010, 14:R34 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Eicosapentaenoic acid preserves diaphragm force generation following endotoxin administration Gerald S Supinski, Jonas Vanags, Leigh Callahan Critical Care 2010, 14:R35 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure Manuel García-Delgado, Ángel Touma-Fernández, Virginia Chamorro-Marín, Antonio Ruiz-Aguilar, Eduardo Aguilar-Alonso, Enrique Fernández-Mondéjar Critical Care 2010, 14:R36 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation: a prospective, multi-centre, observational study Jean-Pierre Quenot, Gaetan Plantefeve, Jean-Luc Baudel, Isabelle Camilatto, Emmanuelle Bertholet, Romain Cailliod, Jean Reignier, Jean-Philippe Rigaud Critical Care 2010, 14:R37 (16 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, the MENDS investigators Critical Care 2010, 14:R38 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease Roselaine Pinheiro de Oliveira, Marcio Hetzel, Mauro dos Anjos Silva, Daniele Dallegrave, Gilberto Friedman Critical Care 2010, 14:R39 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Resuscitation with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injury Nicolas Boussekey, Raphaël Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Enoxaparin, effective dosage for intensive care patients: double-blinded, randomised clinical trial Sian Robinson, Aleksander Zincuk, Thomas Strøm, Torben Larsen, Bjarne Rasmussen, Palle Toft Critical Care 2010, 14:R41 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock Hugo Možina, Matej Podbregar Critical Care 2010, 14:R42 (23 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pulmonary edema and blood volume after aneurysmal subarachnoid hemorrhage: a prospective observational study Reinier G Hoff, Gabriel JE Rinkel, Bon H Verweij, Ale Algra, Cor J Kalkman Critical Care 2010, 14:R43 (23 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prediction of hospital outcome in septic shock: a prospective comparison of tissue Doppler and cardiac biomarkers David J Sturgess, Thomas H Marwick, Chris Joyce, Carly Jenkins, Mark Jones, Paul Masci, David Stewart, Bala Venkatesh Critical Care 2010, 14:R44 (24 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway Rosanna Vaschetto, Jan W Kuiper, René JP Musters, Etto C Eringa, Francesco Della Corte, Kanneganti Murthy, AB Johan Groeneveld, Frans B Plötz Critical Care 2010, 14:R45 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study Nattachai Srisawat, Loredo Lawsin, Shigehiko Uchino, Rinaldo Bellomo, John A Kellum, the BEST Kidney Investigators Critical Care 2010, 14:R46 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Prognostic value of cell-free plasma DNA in patients with cardiac arrest outside the hospital: an observational cohort study Francisco Arnalich, Marta Menéndez, Verónica Lagos, Enrique Ciria, Angustias Quesada, Rosa Codoceo, Juan Vazquez, Eduardo López-Collazo, Carmen Montiel Critical Care 2010, 14:R47 (29 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Elderly patients undergoing mechanical ventilation in and out of intensive care units: a comparative, prospective study of 579 ventilations David Lieberman, Liat Nachshon, Oleg Miloslavsky, Valery Dvorkin, Avi Shimoni, Julian Zelinger, Michael Friger, Devora Lieberman Critical Care 2010, 14:R48 (30 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis Fiia P Gäddnäs, Meeri M Sutinen, Marjo Koskela, Taina Tervahartiala, Timo Sorsa, Tuula A Salo, Jouko J Laurila, Vesa Koivukangas, Tero I Ala-Kokko, Aarne Oikarinen Critical Care 2010, 14:R49 (31 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Impaired cerebrovascular reactivity in sepsis-associated encephalopathy studied by acetazolamide test Szilárd Szatmári, Tamás Végh, Ákos Csomós, Judit Hallay, István Takács, Csilla Molnár, Béla Fülesdi Critical Care 2010, 14:R50 (31 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prospective monitoring of cefepime in intensive care unit adult patients Thomas M Chapuis, Eric Giannoni, Paul A Majcherczyk, René Chioléro, Marie-Denise Schaller, Mette M Berger, Saskia Bolay, Laurent A Décosterd, Denis Bugnon, Philippe Moreillon Critical Care 2010, 14:R51 (1 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Management of bleeding following major trauma: an updated European guideline Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn Critical Care 2010, 14:R52 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock Fabio Taccone, Pierre-François Laterre, Herbert Spapen, Thierry Dugernier, Isabelle Delattre, Brice Layeux, Daniel De Backer, Xavier Wittebole, Pierre Wallemacq, Jean-Louis Vincent, Frédérique Jacobs Critical Care 2010, 14:R53 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Drotrecogin alfa (activated) may attenuate severe sepsis-associated encephalopathy in clinical septic shock Herbert Spapen, Duc Nguyen, Joris Troubleyn, Luc Huyghens, Johan Schiettecatte Critical Care 2010, 14:R54 (7 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM^®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate Herbert Schöchl, Ulrike Nienaber, Georg Hofer, Wolfgang Voelckel, Csilla Jambor, Gisela Scharbert, Sibylle Kozek-Langenecker, Cristina Solomon Critical Care 2010, 14:R55 (7 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of carbon dioxide on near-death experiences in out-of-hospital cardiac arrest survivors: a prospective observational study Zalika Klemenc-Ketis, Janko Kersnik, Stefek Grmec Critical Care 2010, 14:R56 (8 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Increased concentration of carbon dioxide in the blood was associated with the occurrence of near death experiences in a sample of 52 patients surviving out-of-hospital cardiac arrest.
	Research Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study Oliver Karam, Marisa Tucci, Scot T Bateman, Thierry Ducruet, Philip C Spinella, Adrienne G Randolph, Jacques Lacroix Critical Care 2010, 14:R57 (8 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Nicotine withdrawal and agitation in ventilated critically ill patients Olivier Lucidarme, Amélie Seguin, Cédric Daubin, Michel Ramakers, Nicolas Terzi, Patrice Beck, Pierre Charbonneau, Damien du Cheyron Critical Care 2010, 14:R58 (9 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary Severe agitation involving the removal of tubes and catheters and requiring the use of restraints was seen in mechanically ventilated patients experiencing sudden nicotine withdrawal.
	Research A systematic review of the impact of sedation practice in the ICU on resource use, costs and patient safety Daniel L Jackson, Clare W Proudfoot, Kimberley F Cann, Tim Walsh Critical Care 2010, 14:R59 (9 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research One-year mortality, quality of life and predicted life-time cost-utility in critically ill patients with acute respiratory failure Rita Linko, Raili Suojaranta-Ylinen, Sari Karlsson, Esko Ruokonen, Tero Varpula, Ville Pettilä, the FINNALI study investigators Critical Care 2010, 14:R60 (12 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation Oh Kim, Antoine Monsel, Michèle Bertrand, Pierre Coriat, Jean-Marc Cavaillon, Minou Adib-Conquy Critical Care 2010, 14:R61 (13 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury Oliver Grottke, Till Braunschweig, Dietrich Henzler, Mark Coburn, Rene Tolba, Rolf Rossaint Critical Care 2010, 14:R62 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Low hemoglobin is associated with poor functional outcome after non-traumatic, supratentorial intracerebral hemorrhage Jennifer Diedler, Marek Sykora, Philipp Hahn, Kristin Heerlein, Marion N Schölzke, Lars Kellert, Julian Bösel, Sven Poli, Thorsten Steiner Critical Care 2010, 14:R63 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inter-rater reliability of the Full Outline of UnResponsiveness score and the Glasgow Coma Scale in critically ill patients: a prospective observational study Michael Fischer, Stephan Rüegg, Adam Czaplinski, Monika Strohmeier, Angelika Lehmann, Franziska Tschan, Patrick R Hunziker, Stephan C Marsch Critical Care 2010, 14:R64 (14 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study Marcel Schouten, Koenraad F van der Sluijs, Bruce Gerlitz, Brian W Grinnell, Joris JTH Roelofs, Marcel M Levi, Cornelis van 't Veer, Tom Poll Critical Care 2010, 14:R65 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pre-existing disease: the most important factor for health related quality of life long-term after critical illness: a prospective, longitudinal, multicentre trial Lotti Orwelius, Anders Nordlund, Peter Nordlund, Eva Simonsson, Carl Bäckman, Anders Samuelsson, Folke Sjöberg Critical Care 2010, 14:R67 (15 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment Rong-fang Hu, Xiao-ying Jiang, Yi-ming Zeng, Xiao-yang Chen, You-hua Zhang Critical Care 2010, 14:R66 (18 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Febrile neutropenia in French emergency departments: results of a prospective multicentre survey Stéphanie André, Pierre Taboulet, Caroline Elie, Noël Milpied, Michel Nahon, Gérald Kierzek, Mariève Billemont, Franck Perruche, Sandrine Charpentier, Hélène Clément, Jean-Louis Pourriat, Yann-Erick Claessens Critical Care 2010, 14:R68 (19 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Mild therapeutic hypothermia alters neuron specific enolase as an outcome predictor after resuscitation: 97 prospective hypothermia patients compared to 133 historical non-hypothermia patients Ingo G Steffen, Dietrich Hasper, Christoph J Ploner, Joerg C Schefold, Ekkehart Dietz, Frank Martens, Jens Nee, Anne Krueger, Achim Jörres, Christian Storm Critical Care 2010, 14:R69 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inhaled activated protein C protects mice from ventilator-induced lung injury Nikolaos A Maniatis, Eleftheria Letsiou, Stylianos E Orfanos, Matina Kardara, Ioanna Dimopoulou, Georgios Nakos, Marilena E Lekka, Charalambos Roussos, Apostolos Armaganidis, Anastasia Kotanidou Critical Care 2010, 14:R70 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effect of an analgo-sedation protocol for neurointensive patients: a two-phase interventional non-randomized pilot study Ingrid Egerod, Malene Jensen, Suzanne Herling, Karen-Lise Welling Critical Care 2010, 14:R71 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prophylactic anticoagulation to prevent venous thromboembolism in traumatic intracranial hemorrhage: a decision analysis Damon C Scales, Jay Riva-Cambrin, Dave Wells, Valerie Athaide, John T Granton, Allan S Detsky Critical Care 2010, 14:R72 (20 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Re-inspiration of CO₂from ventilator circuit: effects of circuit flushing and aspiration of dead space up to high respiratory rate Edoardo De Robertis, Leif Uttman, Björn Jonson Critical Care 2010, 14:R73 (26 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial Christina Routsi, Vasiliki Gerovasili, Ioannis Vasileiadis, Eleftherios Karatzanos, Theodore Pitsolis, Elli Tripodaki, Vasiliki Markaki, Dimitrios Zervakis, Serafim Nanas Critical Care 2010, 14:R74 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Insulin like growth factor-I in acute subarachnoid hemorrhage: a prospective cohort study Stepani Bendel, Timo Koivisto, Olli-Pekka Ryynänen, Esko Ruokonen, Jarkko Romppanen, Vesa Kiviniemi, Ari Uusaro Critical Care 2010, 14:R75 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study Jean-Michel Constantin, Emmanuel Futier, Anne-Laure Cherprenet, Gérald Chanques, Renaud Guerin, Sophie Cayot-Constantin, Mathieu Jabaudon, Sebastien Perbet, Christian Chartier, Boris Jung, Dominique Guelon, Samir Jaber, Jean-Etienne Bazin Critical Care 2010, 14:R76 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Delta inflation: a bias in the design of randomized controlled trials in critical care medicine Scott K Aberegg, D Roxanne Richards, James M O'Brien Critical Care 2010, 14:R77 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol Daren K Heyland, Naomi E Cahill, Rupinder Dhaliwal, Miao Wang, Andrew G Day, Ahmed Alenzi, Fiona Aris, John Muscedere, John W Drover, Stephen A McClave Critical Care 2010, 14:R78 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research 4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study Krisztina Madách, István Aladzsity, Ágnes Szilágyi, George Fust, János Gál, István Pénzes, Zoltán Prohászka Critical Care 2010, 14:R79 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Early fiberoptic bronchoscopy during non-invasive ventilation in patients with decompensated chronic obstructive pulmonary disease due to community-acquired-pneumonia Raffaele Scala, Mario Naldi, Uberto Maccari Critical Care 2010, 14:R80 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Relatives' evaluation in older patient's quality of life Jean-Pierre Tourtier, Ghislain Nkilly, Karim Tazarourte Critical Care 2010, 14:406 (4 March 2010) Full text \| PDF \| PubMed
	Letter Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection Silvio A Ñamendys-Silva, Marisol Hernández-Garay, Eduardo Rivero-Sigarroa Critical Care 2010, 14:407 (17 March 2010) Full text \| PDF \| PubMed
	Letter Non-invasive ventilation in acute respiratory failure related to 2009 pandemic Influenza A/H1N1 virus infection João Winck, Anabela Marinho Critical Care 2010, 14:408 (19 March 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Dividing intensive care specialists according to their backgrounds is not useful to improve quality in intensive care Jan-Peter Braun, Claudia Spies Critical Care 2010, 14:409 (26 March 2010) Full text \| PDF \| PubMed
	Letter Th17 mediators and vitamin D status Goran Krstić Critical Care 2010, 14:410 (31 March 2010) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Cytokine profiles of suction pulmonary secretions from children infected with pandemic influenza A(H1N1) 2009 Hisashi Kawashima, Soken Go, Yasuyo Kashiwagi, Yasuyuki Morishima, Taro Miura, Masanobu Ushio, Shigeo Nishimata, Kouji Takekuma Critical Care 2010, 14:411 (13 April 2010) Full text \| PDF \| PubMed
	Letter Freeze dried plasma: a French army specialty Jean Daban, Patrick Clapson, Sylvain Ausset, Anne V Deshayes, Anne Sailliol Critical Care 2010, 14:412 (14 April 2010) Full text \| PDF \| PubMed
	Letter Vacuum-assisted closure device in intensive care unit patients and dissemination of Gram-negative bacteria Metaxia N Papanikolaou, Margarita Balla, Panagiotis G Drimousis, Anna Xanthaki, Athanasia Tsirigga, Aikaterini A Charalambous Critical Care 2010, 14:413 (19 April 2010) Full text \| PDF \| PubMed
	Letter A plea for balanced reporting Mervyn Singer Critical Care 2010, 14:414 (20 April 2010) Full text \| PDF \| PubMed
	Letter Noise levels produced by high-frequency oscillation Matt PG Morgan, Nicki Haskins Critical Care 2010, 14:415 (28 April 2010) Full text \| PDF \| PubMed

	Volume 14 Issue 2
	Comment
	Commentary Patients with diabetes in the intensive care unit; not served by treatment, yet protected? Sarah E Siegelaar, J Hans Devries, Joost B Hoekstra Critical Care 2010, 14:126 (1 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Novel representation of physiologic states during critical illness and recovery Timothy G Buchman Critical Care 2010, 14:127 (4 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Pitfalls in haemodynamic monitoring based on the arterial pressure waveform Luigi Camporota, Richard Beale Critical Care 2010, 14:124 (5 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Goal-directed or goal-misdirected - how should we interpret the literature? Anthony M Roche, Timothy E Miller Critical Care 2010, 14:129 (10 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Fish oil-containing lipid emulsions in patients with sepsis Konstantin Mayer, Werner Seeger Critical Care 2010, 14:128 (10 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Critical care in the developing world - a challenge for us all Charles D Gomersall Critical Care 2010, 14:131 (11 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary New versus old blood - the debate continues John Laurie, Duncan Wyncoll, Claire Harrison Critical Care 2010, 14:130 (12 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The kinetics of T regulatory cells in shock: beyond sepsis Eirini Christaki, Eleni Patrozou Critical Care 2010, 14:132 (19 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Can heterogeneity in ventilation be good? Eduardo LV Costa, Marcelo BP Amato Critical Care 2010, 14:134 (22 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Disaster medicine: the caring contradiction David Crippen, Charles Krin, Dean Lorich, Ken Mattox Critical Care 2010, 14:133 (22 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Cardiac arrest - has the time of MRI come? Damien Galanaud, Louis Puybasset Critical Care 2010, 14:135 (26 March 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Where does the lactate come from? A rare cause of reversible inhibition of mitochondrial respiration Bruno Levy, Pierre Perez, Jessica Perny Critical Care 2010, 14:136 (1 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Does anesthetic provide similar neuroprotection to therapeutic hypothermia after cardiac arrest? Hong Zhang Critical Care 2010, 14:137 (8 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Leptin in sepsis: a well-suited biomarker in critically ill patients? Rodolfo Bracho-Riquelme, Miguel Reyes-Romero Critical Care 2010, 14:138 (9 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Clinical features of H1N1 2009 infection in critically ill immunocompromised patients Laurent Camous, Virginie Lemiale, Emmanuel Canet, Adeline Max, David Schnell, Jerome Le Goff, Antoine Rabbat, Benoit Schlemmer, Élie Azoulay Critical Care 2010, 14:139 (14 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Wet lungs, broken hearts and difficult therapies after subarachnoid hemorrhage Nino Stocchetti Critical Care 2010, 14:140 (16 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Statins for acutely hospitalized patients: randomized controlled trials are long overdue Gordon R Bernard Critical Care 2010, 14:141 (19 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Adequate thromboprophylaxis in critically ill patients Marcel Levi Critical Care 2010, 14:142 (21 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary A novel effect of eicosapentaenoic acid: improved diaphragm strength in endotoxemia Philip C Calder Critical Care 2010, 14:143 (23 April 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Inhaled activated protein C: a new therapy for the prevention of ventilator-induced lung injury? Edward Abraham Critical Care 2010, 14:144 (29 April 2010) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Choosing patient-tailored hemodynamic monitoring Cornelis Slagt, Rose-Marieke BGE Breukers, AB Johan Groeneveld Critical Care 2010, 14:208 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Role of CD14 in lung inflammation and infection Adam Anas, Tom Poll, Alex F de Vos Critical Care 2010, 14:209 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review New and conventional strategies for lung recruitment in acute respiratory distress syndrome Paolo Pelosi, Marcelo de Abreu, Patricia RM Rocco Critical Care 2010, 14:210 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Weaning failure of cardiac origin: recent advances Jean-Louis Teboul, Xavier Monnet, Christian Richard Critical Care 2010, 14:211 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Prevention of central venous catheter-related infection in the intensive care unit Denis Frasca, Claire Dahyot-Fizelier, Olivier Mimoz Critical Care 2010, 14:212 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Venous oxygen saturation as a physiologic transfusion trigger Benoit Vallet, Emmanuel Robin, Gilles Lebuffe Critical Care 2010, 14:213 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Renal dysfunction in chronic liver disease Andy Slack, Andrew Yeoman, Julia Wendon Critical Care 2010, 14:214 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Cerebral perfusion in sepsis Christoph S Burkhart, Martin Siegemund, Luzius A Steiner Critical Care 2010, 14:215 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Laparostomy: why and when? Ari K Leppäniemi Critical Care 2010, 14:216 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	Review Patient safety and acute care medicine: lessons for the future, insights from the past Peter G Brindley Critical Care 2010, 14:217 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
	Review Clinical review: Scoring systems in the critically ill Jean-Louis Vincent, Rui Moreno Critical Care 2010, 14:207 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Vaccine protection strategies during pandemic flu outbreaks Joel V Chua, Wilbur H Chen Critical Care 2010, 14:218 (16 April 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Bacterial pneumonia with influenza - pathogenesis and clinical implications Koenraad F van der Sluijs, Tom van der Poll, René Lutter, Nicole P Juffermans, Marcus J Schultz Critical Care 2010, 14:219 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Review Clinical review: Practical recommendations on the management of perioperative heart failure in cardiac surgery Alexandre Mebazaa, Antonis A Pitsis, Alain Rudiger, Wolfgang Toller, Dan Longrois, Sven-Erik Ricksten, Ilona Bobek, Stefan De Hert, Georg Wieselthaler, Uwe Schirmer, Ludwig K von Segesser, Michael Sander, Don Poldermans, Marco Ranucci, Peter CJ Karpati, Patrick Wouters, Manfred Seeberger, Edith R Schmid, Walter Weder, Ferenc Follath Critical Care 2010, 14:201 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Carbon dioxide Gerard Curley, John G Laffey, Brian P Kavanagh Critical Care 2010, 14:220 (30 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: What is the role for autopsy in the ICU? Greet De Vlieger, Elien Mahieu, Wouter Meersseman Critical Care 2010, 14:221 (28 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Report
	Journal club critique The role of noninvasive ventilation in acute cardiogenic pulmonary edema Ashar Salman, Eric B Milbrandt, Michael R Pinsky Critical Care 2010, 14:303 (12 March 2010) Full text \| PDF \| PubMed
	Journal club critique Thrombolysis during out-of-hospital cardiac arrest: a lesson in the law of diminishing returns James M Dargin, Lillian L Emlet Critical Care 2010, 14:304 (22 March 2010) Full text \| PDF \| PubMed
	Journal club critique Intensivists: don't quit your day job...yet! Gregory A Watson, Louis H Alarcon Critical Care 2010, 14:305 (7 April 2010) Full text \| PDF \| PubMed
	Journal club critique Is albumin use SAFE in patients with traumatic brain injury? Christopher R Brackney, Luis A Diaz, Eric B Milbrandt, Ali Al-Khafaji, Joseph M Darby Critical Care 2010, 14:307 (9 April 2010) Full text \| PDF \| PubMed
	Journal club critique Ave, CESAR, morituri te salutant! (Hail, CESAR, those who are about to die salute you!) David J Wallace, Eric B Milbrandt, Arthur Boujoukos Critical Care 2010, 14:308 (26 April 2010) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Book report Cardiopulmonary Bypass Luc Rondelez, Philippe Linden Critical Care 2010, 14:306 (18 March 2010) Full text \| PDF \| PubMed
	Research
	Research Prolonged mechanical ventilation in a respiratory-care setting: a comparison of outcome between tracheostomized and translaryngeal intubated patients Yao-Kuang Wu, Ying-Huang Tsai, Chou-Chin Lan, Chun-Yao Huang, Chih-Hsin Lee, Kuo-Chin Kao, Jui-Ying Fu Critical Care 2010, 14:R26 (1 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Although the type of mechanical ventilation used doesn’t appear to increase successful weaning, patients who are tracheostomized as opposed to translaryngeal intubated are significantly more likely to survive.
	Research Gram-negative bacteremia induces greater magnitude of inflammatory response than Gram-positive bacteremia Ryuzo Abe, Shigeto Oda, Tomohito Sadahiro, Masataka Nakamura, Yo Hirayama, Yoshihisa Tateishi, Koichiro Shinozaki, Hiroyuki Hirasawa Critical Care 2010, 14:R27 (4 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study Thomas Benfield, Karen Ejrnæs, Klaus Juul, Christian Østergaard, Jannik Helweg-Larsen, Nina Weis, Lea Munthe-Fog, Gitte Kronborg, Marianne Andersen, Anne Tybjærg-Hansen, Børge G Nordestgaard, Peter Garred Critical Care 2010, 14:R28 (5 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Preadmission statin use and one-year mortality among patients in intensive care - A cohort study Steffen Christensen, Reimar W Thomsen, Martin B Johansen, Lars Pedersen, Reinhold Jensen, Kim M Larsen, Anders Larsson, Else Tønnesen, Henrik Sørensen Critical Care 2010, 14:R29 (9 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Intensive care unit-acquired infection as a side effect of sedation Saad Nseir, Demosthenes Makris, Daniel Mathieu, Alain Durocher, Charles-Hugo Marquette Critical Care 2010, 14:R30 (15 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Ischemia as a possible effect of increased intra-abdominal pressure on central nervous system cytokines, lactate and perfusion pressures Athanasios Marinis, Eriphili Argyra, Pavlos Lykoudis, Paraskevas Brestas, Kassiani Theodoraki, Georgios Polymeneas, Efstathios Boviatsis, Dionysios Voros Critical Care 2010, 14:R31 (15 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Infections of respiratory or abdominal origin in ICU patients: what are the differences? Elena Volakli, Claudia Spies, Argyris Michalopoulos, AB Johan Groeneveld, Yasser Sakr, Jean-Louis Vincent Critical Care 2010, 14:R32 (15 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research The diagnostic value of serum leptin monitoring and its correlation with tumor necrosis factor-α in critically ill patients: a prospective observational study Ayman Yousef, Yasser Amr, Ghada Suliman Critical Care 2010, 14:R33 (15 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury Marcelo Gama de Abreu, Maximiliano Cuevas, Peter M Spieth, Alysson R Carvalho, Volker Hietschold, Christian Stroszczynski, Bärbel Wiedemann, Thea Koch, Paolo Pelosi, Edmund Koch Critical Care 2010, 14:R34 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Eicosapentaenoic acid preserves diaphragm force generation following endotoxin administration Gerald S Supinski, Jonas Vanags, Leigh Callahan Critical Care 2010, 14:R35 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure Manuel García-Delgado, Ángel Touma-Fernández, Virginia Chamorro-Marín, Antonio Ruiz-Aguilar, Eduardo Aguilar-Alonso, Enrique Fernández-Mondéjar Critical Care 2010, 14:R36 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation: a prospective, multi-centre, observational study Jean-Pierre Quenot, Gaetan Plantefeve, Jean-Luc Baudel, Isabelle Camilatto, Emmanuelle Bertholet, Romain Cailliod, Jean Reignier, Jean-Philippe Rigaud Critical Care 2010, 14:R37 (16 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, the MENDS investigators Critical Care 2010, 14:R38 (16 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease Roselaine Pinheiro de Oliveira, Marcio Hetzel, Mauro dos Anjos Silva, Daniele Dallegrave, Gilberto Friedman Critical Care 2010, 14:R39 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Resuscitation with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injury Nicolas Boussekey, Raphaël Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Enoxaparin, effective dosage for intensive care patients: double-blinded, randomised clinical trial Sian Robinson, Aleksander Zincuk, Thomas Strøm, Torben Larsen, Bjarne Rasmussen, Palle Toft Critical Care 2010, 14:R41 (18 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Near-infrared spectroscopy during stagnant ischemia estimates central venous oxygen saturation and mixed venous oxygen saturation discrepancy in patients with severe left heart failure and additional sepsis/septic shock Hugo Možina, Matej Podbregar Critical Care 2010, 14:R42 (23 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pulmonary edema and blood volume after aneurysmal subarachnoid hemorrhage: a prospective observational study Reinier G Hoff, Gabriel JE Rinkel, Bon H Verweij, Ale Algra, Cor J Kalkman Critical Care 2010, 14:R43 (23 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prediction of hospital outcome in septic shock: a prospective comparison of tissue Doppler and cardiac biomarkers David J Sturgess, Thomas H Marwick, Chris Joyce, Carly Jenkins, Mark Jones, Paul Masci, David Stewart, Bala Venkatesh Critical Care 2010, 14:R44 (24 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway Rosanna Vaschetto, Jan W Kuiper, René JP Musters, Etto C Eringa, Francesco Della Corte, Kanneganti Murthy, AB Johan Groeneveld, Frans B Plötz Critical Care 2010, 14:R45 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study Nattachai Srisawat, Loredo Lawsin, Shigehiko Uchino, Rinaldo Bellomo, John A Kellum, the BEST Kidney Investigators Critical Care 2010, 14:R46 (26 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Prognostic value of cell-free plasma DNA in patients with cardiac arrest outside the hospital: an observational cohort study Francisco Arnalich, Marta Menéndez, Verónica Lagos, Enrique Ciria, Angustias Quesada, Rosa Codoceo, Juan Vazquez, Eduardo López-Collazo, Carmen Montiel Critical Care 2010, 14:R47 (29 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Elderly patients undergoing mechanical ventilation in and out of intensive care units: a comparative, prospective study of 579 ventilations David Lieberman, Liat Nachshon, Oleg Miloslavsky, Valery Dvorkin, Avi Shimoni, Julian Zelinger, Michael Friger, Devora Lieberman Critical Care 2010, 14:R48 (30 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis Fiia P Gäddnäs, Meeri M Sutinen, Marjo Koskela, Taina Tervahartiala, Timo Sorsa, Tuula A Salo, Jouko J Laurila, Vesa Koivukangas, Tero I Ala-Kokko, Aarne Oikarinen Critical Care 2010, 14:R49 (31 March 2010) Abstract \| Full text \| PDF \| PubMed
	Research Impaired cerebrovascular reactivity in sepsis-associated encephalopathy studied by acetazolamide test Szilárd Szatmári, Tamás Végh, Ákos Csomós, Judit Hallay, István Takács, Csilla Molnár, Béla Fülesdi Critical Care 2010, 14:R50 (31 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prospective monitoring of cefepime in intensive care unit adult patients Thomas M Chapuis, Eric Giannoni, Paul A Majcherczyk, René Chioléro, Marie-Denise Schaller, Mette M Berger, Saskia Bolay, Laurent A Décosterd, Denis Bugnon, Philippe Moreillon Critical Care 2010, 14:R51 (1 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Management of bleeding following major trauma: an updated European guideline Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn Critical Care 2010, 14:R52 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock Fabio Taccone, Pierre-François Laterre, Herbert Spapen, Thierry Dugernier, Isabelle Delattre, Brice Layeux, Daniel De Backer, Xavier Wittebole, Pierre Wallemacq, Jean-Louis Vincent, Frédérique Jacobs Critical Care 2010, 14:R53 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Drotrecogin alfa (activated) may attenuate severe sepsis-associated encephalopathy in clinical septic shock Herbert Spapen, Duc Nguyen, Joris Troubleyn, Luc Huyghens, Johan Schiettecatte Critical Care 2010, 14:R54 (7 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM^®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate Herbert Schöchl, Ulrike Nienaber, Georg Hofer, Wolfgang Voelckel, Csilla Jambor, Gisela Scharbert, Sibylle Kozek-Langenecker, Cristina Solomon Critical Care 2010, 14:R55 (7 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of carbon dioxide on near-death experiences in out-of-hospital cardiac arrest survivors: a prospective observational study Zalika Klemenc-Ketis, Janko Kersnik, Stefek Grmec Critical Care 2010, 14:R56 (8 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Increased concentration of carbon dioxide in the blood was associated with the occurrence of near death experiences in a sample of 52 patients surviving out-of-hospital cardiac arrest.
	Research Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study Oliver Karam, Marisa Tucci, Scot T Bateman, Thierry Ducruet, Philip C Spinella, Adrienne G Randolph, Jacques Lacroix Critical Care 2010, 14:R57 (8 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Nicotine withdrawal and agitation in ventilated critically ill patients Olivier Lucidarme, Amélie Seguin, Cédric Daubin, Michel Ramakers, Nicolas Terzi, Patrice Beck, Pierre Charbonneau, Damien du Cheyron Critical Care 2010, 14:R58 (9 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary Severe agitation involving the removal of tubes and catheters and requiring the use of restraints was seen in mechanically ventilated patients experiencing sudden nicotine withdrawal.
	Research A systematic review of the impact of sedation practice in the ICU on resource use, costs and patient safety Daniel L Jackson, Clare W Proudfoot, Kimberley F Cann, Tim Walsh Critical Care 2010, 14:R59 (9 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research One-year mortality, quality of life and predicted life-time cost-utility in critically ill patients with acute respiratory failure Rita Linko, Raili Suojaranta-Ylinen, Sari Karlsson, Esko Ruokonen, Tero Varpula, Ville Pettilä, the FINNALI study investigators Critical Care 2010, 14:R60 (12 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation Oh Kim, Antoine Monsel, Michèle Bertrand, Pierre Coriat, Jean-Marc Cavaillon, Minou Adib-Conquy Critical Care 2010, 14:R61 (13 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effects of different fibrinogen concentrations on blood loss and coagulation parameters in a pig model of coagulopathy with blunt liver injury Oliver Grottke, Till Braunschweig, Dietrich Henzler, Mark Coburn, Rene Tolba, Rolf Rossaint Critical Care 2010, 14:R62 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Low hemoglobin is associated with poor functional outcome after non-traumatic, supratentorial intracerebral hemorrhage Jennifer Diedler, Marek Sykora, Philipp Hahn, Kristin Heerlein, Marion N Schölzke, Lars Kellert, Julian Bösel, Sven Poli, Thorsten Steiner Critical Care 2010, 14:R63 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inter-rater reliability of the Full Outline of UnResponsiveness score and the Glasgow Coma Scale in critically ill patients: a prospective observational study Michael Fischer, Stephan Rüegg, Adam Czaplinski, Monika Strohmeier, Angelika Lehmann, Franziska Tschan, Patrick R Hunziker, Stephan C Marsch Critical Care 2010, 14:R64 (14 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study Marcel Schouten, Koenraad F van der Sluijs, Bruce Gerlitz, Brian W Grinnell, Joris JTH Roelofs, Marcel M Levi, Cornelis van 't Veer, Tom Poll Critical Care 2010, 14:R65 (14 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Pre-existing disease: the most important factor for health related quality of life long-term after critical illness: a prospective, longitudinal, multicentre trial Lotti Orwelius, Anders Nordlund, Peter Nordlund, Eva Simonsson, Carl Bäckman, Anders Samuelsson, Folke Sjöberg Critical Care 2010, 14:R67 (15 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment Rong-fang Hu, Xiao-ying Jiang, Yi-ming Zeng, Xiao-yang Chen, You-hua Zhang Critical Care 2010, 14:R66 (18 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Febrile neutropenia in French emergency departments: results of a prospective multicentre survey Stéphanie André, Pierre Taboulet, Caroline Elie, Noël Milpied, Michel Nahon, Gérald Kierzek, Mariève Billemont, Franck Perruche, Sandrine Charpentier, Hélène Clément, Jean-Louis Pourriat, Yann-Erick Claessens Critical Care 2010, 14:R68 (19 April 2010) Abstract \| Full text \| PDF \| PubMed
	Research Mild therapeutic hypothermia alters neuron specific enolase as an outcome predictor after resuscitation: 97 prospective hypothermia patients compared to 133 historical non-hypothermia patients Ingo G Steffen, Dietrich Hasper, Christoph J Ploner, Joerg C Schefold, Ekkehart Dietz, Frank Martens, Jens Nee, Anne Krueger, Achim Jörres, Christian Storm Critical Care 2010, 14:R69 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inhaled activated protein C protects mice from ventilator-induced lung injury Nikolaos A Maniatis, Eleftheria Letsiou, Stylianos E Orfanos, Matina Kardara, Ioanna Dimopoulou, Georgios Nakos, Marilena E Lekka, Charalambos Roussos, Apostolos Armaganidis, Anastasia Kotanidou Critical Care 2010, 14:R70 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effect of an analgo-sedation protocol for neurointensive patients: a two-phase interventional non-randomized pilot study Ingrid Egerod, Malene Jensen, Suzanne Herling, Karen-Lise Welling Critical Care 2010, 14:R71 (19 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prophylactic anticoagulation to prevent venous thromboembolism in traumatic intracranial hemorrhage: a decision analysis Damon C Scales, Jay Riva-Cambrin, Dave Wells, Valerie Athaide, John T Granton, Allan S Detsky Critical Care 2010, 14:R72 (20 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Re-inspiration of CO₂from ventilator circuit: effects of circuit flushing and aspiration of dead space up to high respiratory rate Edoardo De Robertis, Leif Uttman, Björn Jonson Critical Care 2010, 14:R73 (26 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial Christina Routsi, Vasiliki Gerovasili, Ioannis Vasileiadis, Eleftherios Karatzanos, Theodore Pitsolis, Elli Tripodaki, Vasiliki Markaki, Dimitrios Zervakis, Serafim Nanas Critical Care 2010, 14:R74 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research Insulin like growth factor-I in acute subarachnoid hemorrhage: a prospective cohort study Stepani Bendel, Timo Koivisto, Olli-Pekka Ryynänen, Esko Ruokonen, Jarkko Romppanen, Vesa Kiviniemi, Ari Uusaro Critical Care 2010, 14:R75 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study Jean-Michel Constantin, Emmanuel Futier, Anne-Laure Cherprenet, Gérald Chanques, Renaud Guerin, Sophie Cayot-Constantin, Mathieu Jabaudon, Sebastien Perbet, Christian Chartier, Boris Jung, Dominique Guelon, Samir Jaber, Jean-Etienne Bazin Critical Care 2010, 14:R76 (28 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Delta inflation: a bias in the design of randomized controlled trials in critical care medicine Scott K Aberegg, D Roxanne Richards, James M O'Brien Critical Care 2010, 14:R77 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol Daren K Heyland, Naomi E Cahill, Rupinder Dhaliwal, Miao Wang, Andrew G Day, Ahmed Alenzi, Fiona Aris, John Muscedere, John W Drover, Stephen A McClave Critical Care 2010, 14:R78 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research 4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study Krisztina Madách, István Aladzsity, Ágnes Szilágyi, George Fust, János Gál, István Pénzes, Zoltán Prohászka Critical Care 2010, 14:R79 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Early fiberoptic bronchoscopy during non-invasive ventilation in patients with decompensated chronic obstructive pulmonary disease due to community-acquired-pneumonia Raffaele Scala, Mario Naldi, Uberto Maccari Critical Care 2010, 14:R80 (29 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Relatives' evaluation in older patient's quality of life Jean-Pierre Tourtier, Ghislain Nkilly, Karim Tazarourte Critical Care 2010, 14:406 (4 March 2010) Full text \| PDF \| PubMed
	Letter Non-invasive ventilation for critically ill patients with pandemic H1N1 2009 influenza A virus infection Silvio A Ñamendys-Silva, Marisol Hernández-Garay, Eduardo Rivero-Sigarroa Critical Care 2010, 14:407 (17 March 2010) Full text \| PDF \| PubMed
	Letter Non-invasive ventilation in acute respiratory failure related to 2009 pandemic Influenza A/H1N1 virus infection João Winck, Anabela Marinho Critical Care 2010, 14:408 (19 March 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Dividing intensive care specialists according to their backgrounds is not useful to improve quality in intensive care Jan-Peter Braun, Claudia Spies Critical Care 2010, 14:409 (26 March 2010) Full text \| PDF \| PubMed
	Letter Th17 mediators and vitamin D status Goran Krstić Critical Care 2010, 14:410 (31 March 2010) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Cytokine profiles of suction pulmonary secretions from children infected with pandemic influenza A(H1N1) 2009 Hisashi Kawashima, Soken Go, Yasuyo Kashiwagi, Yasuyuki Morishima, Taro Miura, Masanobu Ushio, Shigeo Nishimata, Kouji Takekuma Critical Care 2010, 14:411 (13 April 2010) Full text \| PDF \| PubMed
	Letter Freeze dried plasma: a French army specialty Jean Daban, Patrick Clapson, Sylvain Ausset, Anne V Deshayes, Anne Sailliol Critical Care 2010, 14:412 (14 April 2010) Full text \| PDF \| PubMed
	Letter Vacuum-assisted closure device in intensive care unit patients and dissemination of Gram-negative bacteria Metaxia N Papanikolaou, Margarita Balla, Panagiotis G Drimousis, Anna Xanthaki, Athanasia Tsirigga, Aikaterini A Charalambous Critical Care 2010, 14:413 (19 April 2010) Full text \| PDF \| PubMed
	Letter A plea for balanced reporting Mervyn Singer Critical Care 2010, 14:414 (20 April 2010) Full text \| PDF \| PubMed
	Letter Noise levels produced by high-frequency oscillation Matt PG Morgan, Nicki Haskins Critical Care 2010, 14:415 (28 April 2010) Full text \| PDF \| PubMed

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