Table 2

Changes of cerebral and spinal perfusion pressures during the four experimental phases (T1 to T4).

T1

(baseline)

T2

(IAP = 20 mmHg)

T3

(IAP = 45 mmHg)

T4

(desufflation)

MAP

85.8 ± 9.62

79.8 ± 11.7

86.8 ± 15.73

84.6 ± 7.37

p

0.186 (T1 vs. T2)

0.297(T2 vs. T3)

0.625 (T3 vs. T4)

ICP

18.7 ± 7.57

25.4 ± 7.79

26.8 ± 9.17

15.3 ± 3.65

p

<0.001(T1 vs. T2)

0.485 (T2 vs. T3)

<0.001 (T3 vs. T4)

CPP

67.1 ± 13.81

54.4 ± 9.77

60 ± 16.54

69.3 ± 8.38

p

0.013 (T1 vs. T2)

0.392 (T2 vs. T3)

0.057 (T3 vs. T4)

ISP

13.2 ± 3.26

25.4 ± 8.36

22.3 ± 8

12.3 ± 3.86

p

0.001(T1 vs. T2)

0.375 (T2 vs. T3)

0.005 (T3 vs. T4)

SPP

72.6 ± 10.95

54.4 ± 10.6

64.5 ± 21.57

72.3 ± 7.42

p

0.002 (T1 vs. T2)

0.198 (T2 vs. T3)

0.235 (T3 vs. T4)

CPP is calculated as mean arterial pressure (MAP) minus intracranial pressure (ICP), while SPP as MAP minus intraspinal pressure (ISP). All pressures are displayed as mean ± SD and expressed as mmHg. Statistical significances (p < 0.05) are marked with bold. IAP: intra-abdominal pressure.

Marinis et al. Critical Care 2010 14:R31   doi:10.1186/cc8908