Diaphragm calpain activity. Diaphragm calpain activity was significantly increased for samples taken from animals after LPS treatment (filled bar) as compared to controls (open bar) (P < 0.001). EPA administration reduced this increase in diaphragm calpain activity, with calpain activity lower for the EPA plus LPS group (light grey bar) as compared to LPS treated animals (P < 0.02). Diaphragm calpain activity for samples from animals given EPA alone (dark grey bar) was similar to levels for the control group. * indicates a significant statistical difference from the other groups.
Supinski et al. Critical Care 2010 14:R35 doi:10.1186/cc8913