Table 1 |
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|
Extravascular lung water and respiratory and hemodynamic parameters. |
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|
Baseline |
0 |
60 minutes |
120 minutes |
180 minutes |
240 minutes |
|
|
|
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|
EVLW (ml) |
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|
SE |
286 (72) a |
421 (93) |
395 (81) |
356 (57) |
346 (58) |
344 (63) |
|
LE |
225 (30) a |
458 (42) |
415 (34) |
387 (27) |
354 (40) |
331 (45) |
|
SE+PEEP |
309 (80) a |
446 (64) |
383 (60) |
371 (70) |
367 (75) |
363 (73) |
|
LE+PEEP |
269 (37) a |
491 (56) b |
436 (28) b |
389 (54) |
366 (43) |
349 (46) |
|
PaO2/FiO2 |
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|
SE |
346 (148) b |
167 (91) |
193 (95) |
204 (121) |
216 (134) |
221 (141) |
|
LE |
416 (128) b |
100 (36) |
96 (49) |
118 (44) |
169 (62) |
183 (54) |
|
SE+PEEP |
269 (156) |
420 (74) c |
432 (89) c |
424 (107) c |
403 (127) c |
425 (121) c |
|
LE+PEEP |
437 (69) |
202 (93) d |
262 (144) d |
401 (141) d |
505 (29) d |
539 (27) d |
|
Pplat (mmHg) |
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|
SE |
11.8 (2.7) a |
15.3 (1.7) |
15.4 (2.2) |
15.3 (1.9) |
15.1 (2.2) |
14.9 (2.0) |
|
LE |
10.8 (2.3) a |
17.1 (1.5) |
16.2 (3.0) |
15.2 (1.9) |
15.2 (2.3) |
15.4 (2.4) |
|
SE+PEEP |
14.8 (3.4) a |
23.4 (3.1) e |
23.2 (1.6) e |
23.2 (1.7) e |
23.2 (1.7) e |
23.1 (1.8) e |
|
LE+PEEP |
14.4 (4.5) a |
27.4 (7.4) f |
26.6 (4.9) f |
26.9 (4.7) f |
25.8 (4.3) f |
25.8 (4.7) f |
|
MAP(mmHg) |
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|
SE |
68.2 (9.5) |
68.2 (9.3) a |
76.9 (12.3) |
82.7 (10.5) |
84.3 (9.6) |
87.3 (10.8) |
|
LE |
77.2 (10.7) |
77.0 (5.1) |
80.2 (6.8) |
77.4 (5.7) |
81.2 (10.7) |
82.4 (12.8) |
|
SE+PEEP |
59.0 (8.3) |
61.7 (5.5) |
69.8 (8.2) |
75.0 (9.6) |
76.2 (12.7) |
77.4 (13.3) |
|
LE+PEEP |
70.4 (13.8) g |
52.4 (10.5) |
63.2 (5.4) |
66.8 (4.8) |
64.4 (4.8) |
64.7 (5.0) |
|
CO (L/min) |
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|
SE |
3.7 (0.9) |
3.9 (1.0) |
4.5 (1.2) |
4.7 (0.9) |
4.6 (0.9) |
4.5 (0.9) |
|
LE |
3.9 (1.2) |
3.9 (0.9) |
4.6 (1.4) |
4.5 (1.2) |
4.1 (0.9) |
3.9 (0.9) |
|
SE+PEEP |
3.9 (0.7) |
4.7 (0.8) |
4.4 (0.9) |
4.2 (0.8) |
4.3 (0.9) |
4.1 (1.0) |
|
LE+PEEP |
3.8 (1.1) b |
3.0 (1.0) d |
3.9 (0.8) d |
3.7 (0.9) d |
3.4 (0.8) d |
3.2 (0.7) d |
|
|
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|
Data are expressed as mean (SD). a Statistically significant differences with subsequent time points (P < 0.01). b Statistically significant differences with subsequent time points (P < 0.05). c Statistically significant differences between SE and SE + PEEP groups (P < 0.05). d Statistically significant differences between LE and LE + PEEP groups (P < 0.05). e Statistically significant differences between SE and SE + PEEP groups (P < 0.01). f Statistically significant differences between LE and LE + PEEP groups (P < 0.01). g Statistically significant differences between baseline and time 0 (P < 0.05). CO, cardiac output; EVLW, extravascular lung water; LE, large edema; LE + PEEP, large edema + positive end-expiratory pressure; MAP, mean arterial pressure; Pplat, plateau pressure; SE, small edema; SE + PEEP, small edema + positive end-expiratory pressure. |
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|
García-Delgado et al. Critical Care 2010 14:R36 doi:10.1186/cc8914 |
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