Research

Delta inflation: a bias in the design of randomized controlled trials in critical care medicine

Scott K Aberegg¹^*, D Roxanne Richards² and James M O'Brien³

¹ Department of Critical Care, Jordan Valley Medical Center, 3580 West 9000 South, West Jordan, Utah, 84088, USA

² Department of Family Medicine, University of Virginia Health System, 1215 Lee Street, Charlottesville, Virginia, 22908, USA

³ Department of Internal Medicine, The Ohio State University College of Medicine, 410 West 10th Avenue, Columbus, Ohio, 43210, USA

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Critical Care 2010, 14:R77 doi:10.1186/cc8990

See related letter by Roozenbeek et al., http://ccforum.com/content/14/3/423

Published: 29 April 2010

Additional file 1:

Table S2. Selected characteristics of studies included in the analysis.

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