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Highly Accessed Letter

Heparin algorithm for anticoagulation during continuous renal replacement therapy

Marlies Ostermann*, Helen Dickie, Linda Tovey and David Treacher

Author Affiliations

Guy's & St Thomas' Foundation Trust, Department of Critical Care, Westminster Bridge Road, London SE17EH, UK

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Critical Care 2010, 14:419 doi:10.1186/cc9003

Published: 27 May 2010

Abstract

Premature circuit clotting is a problem during continuous renal replacement therapy. We describe an algorithm for individualised anticoagulation with unfractionated heparin based on the patient's risk of bleeding and previous circuit life. The algorithm allows effective and safe nurse-led anticoagulation during continuous renal replacement therapy.