Critical Care | Volume 14 Issue 4

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	Volume 14 Issue 4
	Comment
	Viewpoint Concepts in hypoxia reborn Daniel S Martin, Maryam Khosravi, Mike PW Grocott, Michael G Mythen Critical Care 2010, 14:315 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Do recruitment maneuvers simply improve oxygenation? Franco Valenza Critical Care 2010, 14:173 (1 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Hemodynamic changes during weaning: can we assess and predict cardiac-related weaning failure by transthoracic echocardiography? Gorazd Voga Critical Care 2010, 14:174 (7 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Pulse pressure analysis: to make a long story short Maurizio Cecconi, Andrew Rhodes Critical Care 2010, 14:175 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The dilemma of good clinical practice in the study of compromised standards of care Yechiel M Barilan Critical Care 2010, 14:176 (15 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Improving surgical outcomes: it is the destination not the journey Jonathan Wilson, Simon Davies Critical Care 2010, 14:177 (16 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Hot times in the intensive care unit Edward Abraham Critical Care 2010, 14:178 (19 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis-related stress response: known knowns, known unknowns, and unknown unknowns Jinmin Peng, Bin Du Critical Care 2010, 14:179 (19 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Macrolides and community-acquired pneumonia: is quorum sensing the key? Matt P Wise, David W Williams, Michael AO Lewis, Paul J Frost Critical Care 2010, 14:181 (20 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Does low angiopoietin-1 predict adverse outcome in sepsis? Sascha David, Matijs van Meurs, Philipp Kümpers Critical Care 2010, 14:180 (20 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Atrial fibrillation is not just an artefact in the ICU Philippe Seguin, Yoann Launey Critical Care 2010, 14:182 (22 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids for sepsis: registry versus Cochrane systematic review! Djillali Annane Critical Care 2010, 14:185 (30 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The role of inflammation in ICU-acquired weakness Chris Winkelman Critical Care 2010, 14:186 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Diaphragm weakness and mechanical ventilation - what's the critical issue? Leigh Callahan, Gerald S Supinski Critical Care 2010, 14:187 (4 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful? John Dixon, Barbara Philips Critical Care 2010, 14:184 (6 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Activated protein C in severe acute pancreatitis without sepsis? Not just yet ... Manu Shankar-Hari, Duncan Wyncoll Critical Care 2010, 14:188 (9 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Assessing the quantity of pulmonary edema in critically ill children Daniel F McAuley, Lisa M Brown, Michael A Matthay Critical Care 2010, 14:189 (13 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Right man, right time, right place? - On the time course of the mediator orchestra in septic shock Balázs Hauser, Peter Radermacher Critical Care 2010, 14:190 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Safer ventilation of the injured lung: one step closer John J Marini Critical Care 2010, 14:192 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Is enough oxygen too much? Paul T Schumacker Critical Care 2010, 14:191 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Bench-to-bedside review: Chloride in critical illness Nor'azim Yunos, Rinaldo Bellomo, David Story, John Kellum Critical Care 2010, 14:226 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench to bedside: A role for erythropoietin in sepsis Andrew P Walden, J Duncan Young, Edward Sharples Critical Care 2010, 14:227 (6 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection Robert Dickinson, Nicholas P Franks Critical Care 2010, 14:229 (12 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis Helen F Galley Critical Care 2010, 14:230 (20 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Glucose and stress conditions in the intensive care unit Marie-Reine Losser, Charles Damoisel, Didier Payen Critical Care 2010, 14:231 (20 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation? Andrew W Kirkpatrick, Paolo Pelosi, Jan J De Waele, Manu LNG Malbrain, Chad G Ball, Maureen O Meade, Henry T Stelfox, Kevin B Laupland Critical Care 2010, 14:232 (27 August 2010) Abstract \| Full text \| PDF \| PubMed
	Report
	Journal club critique Clearing up the confusion: The results of two pilot studies of antipsychotics for ICU delirium Zaher Qassem, Eric B Milbrandt Critical Care 2010, 14:316 (11 August 2010) Full text \| PDF \| PubMed
	Journal club critique NGAL: an emerging tool for predicting severity of AKI is easily detected by a clinical assay Wes Gabbard, Eric B Milbrandt, John A Kellum Critical Care 2010, 14:318 (23 August 2010) Full text \| PDF \| PubMed
	Correction Extravascular lung water index measurement in critically ill children does not correlate with a chest x-ray score of pulmonary edema Joris Lemson, Lya E van Die, Anique EA Hemelaar, Johannes G van der Hoeven Critical Care 2010, 14:430 (26 July 2010) Full text \| PDF \| PubMed
	Book report Critical Care Medicine: The Essentials Daniel De Backer Critical Care 2010, 14:317 (9 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock Fabio Silvio Taccone, Pierre-François Laterre, Thierry Dugernier, Herbert Spapen, Isabelle Delattre, Xavier Wittebole, Daniel De Backer, Brice Layeux, Pierre Wallemacq, Jean-Louis Vincent, Frédérique Jacobs Critical Care 2010, 14:R126 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study Greet Hermans, Anouk Agten, Dries Testelmans, Marc Decramer, Ghislaine Gayan-Ramirez Critical Care 2010, 14:R127 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Commonly applied positive end-expiratory pressures do not prevent functional residual capacity decline in the setting of intra-abdominal hypertension: a pig model Adrian Regli, Lisen E Hockings, Gabrielle C Musk, Brigit Roberts, Bill Noffsinger, Bhajan Singh, Peter V van Heerden Critical Care 2010, 14:R128 (2 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model Matthias Lange, Rhykka Connelly, Daniel L Traber, Atsumori Hamahata, Yoshimitsu Nakano, Aimalohi Esechie, Collette Jonkam, Sanna von Borzyskowski, Lillian D Traber, Frank C Schmalstieg, David N Herndon, Perenlei Enkhbaatar Critical Care 2010, 14:R129 (5 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes Ivan Gornik, Ana Vujaklija-Brajković, Ivana Renar, Vladimir Gašparović Critical Care 2010, 14:R130 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Patients with a high blood sugar level in the ICU have an increased risk of developing diabetes in later life and should be monitored regularly and treated appropriately after discharge.
	Research Proven infection-related sepsis induces a differential stress response early after ICU admission Olivier Lesur, Jean-Francois Roussy, Frederic Chagnon, Nicole Gallo-Payet, Robert Dumaine, Philippe Sarret, Ahmed Chraibi, Lucie Chouinard, Bruno Hogue Critical Care 2010, 14:R131 (9 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Physicians' and nurses' opinions on selective decontamination of the digestive tract and selective oropharyngeal decontamination: a survey Irene P Jongerden, Anne Marie G de Smet, Jan A Kluytmans, Leo F te Velde, Paul J Dennesen, Ronald M Wesselink, Martijn P Bouw, Rob Spanjersberg, Diana Bogaers-Hofman, Nardo J van der Meer, Jaap W de Vries, Karin Kaasjager, Mat van Iterson, Georg H Kluge, Tjip S van der Werf, Hubertus I Harinck, Alexander J Bindels, Peter Pickkers, Marc J Bonten Critical Care 2010, 14:R132 (13 July 2010) Abstract \| Full text \| PDF \| PubMed
	Research Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients Fanny Turrel-Davin, Caroline Guignant, Alain Lepape, Bruno Mougin, Guillaume Monneret, Fabienne Venet Critical Care 2010, 14:R133 (13 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective John L Moran, Petra L Graham, Sue Rockliff, Andrew D Bersten Critical Care 2010, 14:R134 (13 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury Qin Lu, Mao Zhang, Cassio Girardi, Belaïd Bouhemad, Jozef Kesecioglu, Jean-Jacques Rouby Critical Care 2010, 14:R135 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Administration of an exogenous surfactant induces significant and prolonged aeration in patients with acute lung injury, but the question of whether a more selective instillation would be beneficial remains unanswered.
	Research Predictors for good functional outcome after neurocritical care Ines C Kiphuth, Peter D Schellinger, Martin Köhrmann, Jürgen Bardutzky, Hannes Lücking, Stephan Kloska, Stefan Schwab, Hagen B Huttner Critical Care 2010, 14:R136 (20 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/acute respiratory distress syndrome patients: a pilot study Daniel Verzilli, Jean-Michel Constantin, Mustapha Sebbane, Gérald Chanques, Boris Jung, Pierre-François Perrigault, Manu Malbrain, Samir Jaber Critical Care 2010, 14:R137 (21 July 2010) Abstract \| Full text \| PDF \| PubMed
	Research Standardized intensive care unit management in an anhepatic pig model: new standards for analyzing liver support systems Christian Thiel, Karolin Thiel, Alexander Etspueler, Thomas Schenk, Matthias H Morgalla, Alfred Koenigsrainer, Martin Schenk Critical Care 2010, 14:R138 (22 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research APCAP - activated protein C in acute pancreatitis: a double-blind randomized human pilot trial Ville Pettilä, Lea Kyhälä, Marja-Leena Kylänpää, Ari Leppäniemi, Minna Tallgren, Antti Markkola, Pauli Puolakkainen, Heikki Repo, Esko Kemppainen Critical Care 2010, 14:R139 (27 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Cerebral microcirculation is impaired during sepsis: an experimental study Fabio Silvio Taccone, Fuhong Su, Charalampos Pierrakos, Xinrong He, Syril James, Olivier Dewitte, Jean-Louis Vincent, Daniel De Backer Critical Care 2010, 14:R140 (28 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials Hassan Siddiki, Marija Kojicic, Guangxi Li, Murat Yilmaz, Taylor B Thompson, Rolf D Hubmayr, Ognjen Gajic Critical Care 2010, 14:R141 (29 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension Olfa Hamzaoui, Jean-François Georger, Xavier Monnet, Hatem Ksouri, Julien Maizel, Christian Richard, Jean-Louis Teboul Critical Care 2010, 14:R142 (29 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Simvastatin attenuates ventilator-induced lung injury in mice Holger C Müller, Katharina Hellwig, Simone Rosseau, Thomas Tschernig, Andreas Schmiedl, Birgitt Gutbier, Bernd Schmeck, Stefan Hippenstiel, Harm Peters, Lars Morawietz, Norbert Suttorp, Martin Witzenrath Critical Care 2010, 14:R143 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Retrospective agreement and consent to neurocritical care is influenced by functional outcome Ines C Kiphuth, Martin Köhrmann, Joji B Kuramatsu, Christoph Mauer, Lorenz Breuer, Peter D Schellinger, Stefan Schwab, Hagen B Huttner Critical Care 2010, 14:R144 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Identifying predictors for severe disability after ICU treatment would aid physicians in deciding whether to initiate neurocritical care, as rates of retrospective consent are lowest in patients with a poor functional outcome.
	Research Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study Marcel Schouten, Cornelis van't Veer, Joris JTH Roelofs, Marcel Levi, Tom van der Poll Critical Care 2010, 14:R145 (3 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research The impact of delirium on the prediction of in-hospital mortality in intensive care patients Mark van den Boogaard, Sanne AE Peters, Johannes G van der Hoeven, Pieter C Dagnelie, Pieter Leffers, Peter Pickkers, Lisette Schoonhoven Critical Care 2010, 14:R146 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Treatment of hypophosphatemia in the intensive care unit: a review Daniël A Geerse, Alexander J Bindels, Michael A Kuiper, Arnout N Roos, Peter E Spronk, Marcus J Schultz Critical Care 2010, 14:R147 (3 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis Michael Sander, Claudia D Spies, Viktoria Martiny, Christoph Rosenthal, Klaus-Dieter Wernecke, Christian von Heymann Critical Care 2010, 14:R148 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology \| Editor’s summary An association with higher mortality and minor efficiency of tranexamic acid raises questions about the routine high dose administration of the drug in cardiac surgery, according to a retrospective study.
	Research Central venous oxygen saturation and blood lactate levels during cardiopulmonary bypass are associated with outcome after pediatric cardiac surgery Marco Ranucci, Giuseppe Isgrò, Concetta Carlucci, Teresa De La Torre, Stefania Enginoli, Alessandro Frigiola, Surgical and Clinical Outcome REsearch (SCORE) Group Critical Care 2010, 14:R149 (4 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A systematic review of randomized controlled trials exploring the effect of immunomodulative interventions on infection, organ failure, and mortality in trauma patients Nicole E Spruijt, Tjaakje Visser, Luke PH Leenen Critical Care 2010, 14:R150 (5 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The administration of immunoglobulin, interferon-γ or glucan may improve outcomes in trauma patients, for whom inflammatory complications such as multiple organ failure are the most common cause of late death.
	Research Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial Shaman Jhanji, Amanda Vivian-Smith, Susana Lucena-Amaro, David Watson, Charles J Hinds, Rupert M Pearse Critical Care 2010, 14:R151 (10 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Sepsis is a major determinant of outcome in critically ill HIV/AIDS patients André M Japiassú, Rodrigo T Amâncio, Emerson C Mesquita, Denise M Medeiros, Helena B Bernal, Estevão P Nunes, Paula M Luz, Beatriz Grinsztejn, Fernando A Bozza Critical Care 2010, 14:R152 (10 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Severe sepsis is a major cause of mortality for hospitalised HIV/AIDS patients and significantly decreases short- and longer-term survival, finds a study of 88 HIV patients admitted to the intensive care unit.
	Research The use of exenatide in severely burned pediatric patients Gabriel A Mecott, David N Herndon, Gabriela A Kulp, Natasha C Brooks, Ahmed M Al-Mousawi, Robert Kraft, Haidy G Rivero, Felicia N Williams, Ludwik K Branski, Marc G Jeschke Critical Care 2010, 14:R153 (11 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Exenatide was found to be as effective as intensive insulin treatment in decreasing plasma glucose levels, and may represent a novel agent to attenuate hyperglycemia in the critical care setting.
	Research Organ failure and tight glycemic control in the SPRINT study J Geoffrey Chase, Christopher G Pretty, Leesa Pfeifer, Geoffrey M Shaw, Jean-Charles Preiser, Aaron J Le Compte, Jessica Lin, Darren Hewett, Katherine T Moorhead, Thomas Desaive Critical Care 2010, 14:R154 (12 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Who benefits most from mild therapeutic hypothermia in coronary intervention era? A retrospective and propensity-matched study Eisuke Kagawa, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Satoshi Kurisu, Yasuharu Nakama, Kazuoki Dai, Takayuki Otani, Hiroki Ikenaga, Yoshimasa Morimoto, Kentaro Ejiri, Nozomu Oda Critical Care 2010, 14:R155 (16 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Human protein C concentrate in the treatment of purpura fulminans: a retrospective analysis of safety and outcome in 94 pediatric patients Alex Veldman, Doris Fischer, Flora Y Wong, Wolfhart Kreuz, Michael Sasse, Bruno Eberspächer, Ulrich Mansmann, Rudolf Schosser Critical Care 2010, 14:R156 (19 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Interferon-β attenuates lung inflammation following experimental subarachnoid hemorrhage Pieter M Cobelens, Ivo ACW Tiebosch, Rick M Dijkhuizen, Peter H van der Meide, René Zwartbol, Cobi J Heijnen, Jozef Kesecioglu, Walter M van den Bergh Critical Care 2010, 14:R157 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes Carl Ekman, Adam Linder, Per Åkesson, Björn Dahlbäck Critical Care 2010, 14:R158 (23 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection kit Katsunori Yanagihara, Yuko Kitagawa, Masao Tomonaga, Kunihiro Tsukasaki, Shigeru Kohno, Masafumi Seki, Hisashi Sugimoto, Takeshi Shimazu, Osamu Tasaki, Asako Matsushima, Yasuo Ikeda, Shinichiro Okamoto, Naoki Aikawa, Shingo Hori, Hideaki Obara, Akitoshi Ishizaka, Naoki Hasegawa, Junzo Takeda, Shimeru Kamihira, Kazuyuki Sugahara, Seishi Asari, Mitsuru Murata, Yoshio Kobayashi, Hiroyuki Ginba, Yoshinobu Sumiyama, Masaki Kitajima Critical Care 2010, 14:R159 (24 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice Joëlle Rolli, Noureddine Loukili, Sandra Levrand, Nathalie Rosenblatt-Velin, Stéphanie Rignault-Clerc, Bernard Waeber, François Feihl, Pal Pacher, Lucas Liaudet Critical Care 2010, 14:R160 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow Luuk DH Munsterman, Paul WG Elbers, Alaattin Ozdemir, Eric PA van Dongen, Mat van Iterson, Can Ince Critical Care 2010, 14:R161 (25 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter The role for autopsy in the intensive care unit: technological considerations Carlos E Pompilio Critical Care 2010, 14:426 (5 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Another explanation for decreased oxygen consumption in lactic acidosis Viktor Rosival Critical Care 2010, 14:427 (6 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Electrical muscle stimulation for prevention of critical illness polyneuropathy Pablo O Rodriguez, Mariano Setten, Ricardo Valentini Critical Care 2010, 14:428 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter To transfuse or not to transfuse: thinking outside the box Yasser Sakr, Konrad Reinhart Critical Care 2010, 14:431 (27 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Assessment of monocytic HLA-DR expression in ICU patients: analytical issues for multicentric flow cytometry studies Guillaume Monneret, Fabienne Venet, Christian Meisel, Joerg C Schefold Critical Care 2010, 14:432 (27 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Is routine autopsy in the intensive care unit viable? Authors' response Greet De Vlieger, Elien Mahieu, Wouter Meersseman Critical Care 2010, 14:433 (29 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Alpha-2 adrenoceptor agonists and sepsis: improved survival? Luc Quintin Critical Care 2010, 14:429 (29 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Quality of life in patients aged 80 or over after intensive care unit discharge Jacqueline Koeze, Jan G Zijlstra Critical Care 2010, 14:434 (30 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Understanding immune dysfunctions in sepsis patients Eduardo López-Collazo, Vanesa Gómez-Piña, Francisco Arnalich Critical Care 2010, 14:435 (10 August 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Heterogeneity in ventilation during positive end-expiratory pressure Mukesh Tripathi, Mamta Pandey Critical Care 2010, 14:436 (17 August 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Lung reaeration after surfactant instillation - caused by surfactant or caused by instillation? Marcus J Schultz Critical Care 2010, 14:437 (20 August 2010) Abstract \| Full text \| PDF \| PubMed

	Volume 14 Issue 4
	Comment
	Viewpoint Concepts in hypoxia reborn Daniel S Martin, Maryam Khosravi, Mike PW Grocott, Michael G Mythen Critical Care 2010, 14:315 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Do recruitment maneuvers simply improve oxygenation? Franco Valenza Critical Care 2010, 14:173 (1 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Hemodynamic changes during weaning: can we assess and predict cardiac-related weaning failure by transthoracic echocardiography? Gorazd Voga Critical Care 2010, 14:174 (7 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Pulse pressure analysis: to make a long story short Maurizio Cecconi, Andrew Rhodes Critical Care 2010, 14:175 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The dilemma of good clinical practice in the study of compromised standards of care Yechiel M Barilan Critical Care 2010, 14:176 (15 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Improving surgical outcomes: it is the destination not the journey Jonathan Wilson, Simon Davies Critical Care 2010, 14:177 (16 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Hot times in the intensive care unit Edward Abraham Critical Care 2010, 14:178 (19 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis-related stress response: known knowns, known unknowns, and unknown unknowns Jinmin Peng, Bin Du Critical Care 2010, 14:179 (19 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Macrolides and community-acquired pneumonia: is quorum sensing the key? Matt P Wise, David W Williams, Michael AO Lewis, Paul J Frost Critical Care 2010, 14:181 (20 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Does low angiopoietin-1 predict adverse outcome in sepsis? Sascha David, Matijs van Meurs, Philipp Kümpers Critical Care 2010, 14:180 (20 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Atrial fibrillation is not just an artefact in the ICU Philippe Seguin, Yoann Launey Critical Care 2010, 14:182 (22 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids for sepsis: registry versus Cochrane systematic review! Djillali Annane Critical Care 2010, 14:185 (30 July 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The role of inflammation in ICU-acquired weakness Chris Winkelman Critical Care 2010, 14:186 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Diaphragm weakness and mechanical ventilation - what's the critical issue? Leigh Callahan, Gerald S Supinski Critical Care 2010, 14:187 (4 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful? John Dixon, Barbara Philips Critical Care 2010, 14:184 (6 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Activated protein C in severe acute pancreatitis without sepsis? Not just yet ... Manu Shankar-Hari, Duncan Wyncoll Critical Care 2010, 14:188 (9 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Assessing the quantity of pulmonary edema in critically ill children Daniel F McAuley, Lisa M Brown, Michael A Matthay Critical Care 2010, 14:189 (13 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Right man, right time, right place? - On the time course of the mediator orchestra in septic shock Balázs Hauser, Peter Radermacher Critical Care 2010, 14:190 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Safer ventilation of the injured lung: one step closer John J Marini Critical Care 2010, 14:192 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Commentary Is enough oxygen too much? Paul T Schumacker Critical Care 2010, 14:191 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Bench-to-bedside review: Chloride in critical illness Nor'azim Yunos, Rinaldo Bellomo, David Story, John Kellum Critical Care 2010, 14:226 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench to bedside: A role for erythropoietin in sepsis Andrew P Walden, J Duncan Young, Edward Sharples Critical Care 2010, 14:227 (6 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection Robert Dickinson, Nicholas P Franks Critical Care 2010, 14:229 (12 August 2010) Abstract \| Full text \| PDF \| PubMed
	Review Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis Helen F Galley Critical Care 2010, 14:230 (20 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Glucose and stress conditions in the intensive care unit Marie-Reine Losser, Charles Damoisel, Didier Payen Critical Care 2010, 14:231 (20 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation? Andrew W Kirkpatrick, Paolo Pelosi, Jan J De Waele, Manu LNG Malbrain, Chad G Ball, Maureen O Meade, Henry T Stelfox, Kevin B Laupland Critical Care 2010, 14:232 (27 August 2010) Abstract \| Full text \| PDF \| PubMed
	Report
	Journal club critique Clearing up the confusion: The results of two pilot studies of antipsychotics for ICU delirium Zaher Qassem, Eric B Milbrandt Critical Care 2010, 14:316 (11 August 2010) Full text \| PDF \| PubMed
	Journal club critique NGAL: an emerging tool for predicting severity of AKI is easily detected by a clinical assay Wes Gabbard, Eric B Milbrandt, John A Kellum Critical Care 2010, 14:318 (23 August 2010) Full text \| PDF \| PubMed
	Correction Extravascular lung water index measurement in critically ill children does not correlate with a chest x-ray score of pulmonary edema Joris Lemson, Lya E van Die, Anique EA Hemelaar, Johannes G van der Hoeven Critical Care 2010, 14:430 (26 July 2010) Full text \| PDF \| PubMed
	Book report Critical Care Medicine: The Essentials Daniel De Backer Critical Care 2010, 14:317 (9 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock Fabio Silvio Taccone, Pierre-François Laterre, Thierry Dugernier, Herbert Spapen, Isabelle Delattre, Xavier Wittebole, Daniel De Backer, Brice Layeux, Pierre Wallemacq, Jean-Louis Vincent, Frédérique Jacobs Critical Care 2010, 14:R126 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study Greet Hermans, Anouk Agten, Dries Testelmans, Marc Decramer, Ghislaine Gayan-Ramirez Critical Care 2010, 14:R127 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Commonly applied positive end-expiratory pressures do not prevent functional residual capacity decline in the setting of intra-abdominal hypertension: a pig model Adrian Regli, Lisen E Hockings, Gabrielle C Musk, Brigit Roberts, Bill Noffsinger, Bhajan Singh, Peter V van Heerden Critical Care 2010, 14:R128 (2 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model Matthias Lange, Rhykka Connelly, Daniel L Traber, Atsumori Hamahata, Yoshimitsu Nakano, Aimalohi Esechie, Collette Jonkam, Sanna von Borzyskowski, Lillian D Traber, Frank C Schmalstieg, David N Herndon, Perenlei Enkhbaatar Critical Care 2010, 14:R129 (5 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes Ivan Gornik, Ana Vujaklija-Brajković, Ivana Renar, Vladimir Gašparović Critical Care 2010, 14:R130 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Patients with a high blood sugar level in the ICU have an increased risk of developing diabetes in later life and should be monitored regularly and treated appropriately after discharge.
	Research Proven infection-related sepsis induces a differential stress response early after ICU admission Olivier Lesur, Jean-Francois Roussy, Frederic Chagnon, Nicole Gallo-Payet, Robert Dumaine, Philippe Sarret, Ahmed Chraibi, Lucie Chouinard, Bruno Hogue Critical Care 2010, 14:R131 (9 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Physicians' and nurses' opinions on selective decontamination of the digestive tract and selective oropharyngeal decontamination: a survey Irene P Jongerden, Anne Marie G de Smet, Jan A Kluytmans, Leo F te Velde, Paul J Dennesen, Ronald M Wesselink, Martijn P Bouw, Rob Spanjersberg, Diana Bogaers-Hofman, Nardo J van der Meer, Jaap W de Vries, Karin Kaasjager, Mat van Iterson, Georg H Kluge, Tjip S van der Werf, Hubertus I Harinck, Alexander J Bindels, Peter Pickkers, Marc J Bonten Critical Care 2010, 14:R132 (13 July 2010) Abstract \| Full text \| PDF \| PubMed
	Research Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients Fanny Turrel-Davin, Caroline Guignant, Alain Lepape, Bruno Mougin, Guillaume Monneret, Fabienne Venet Critical Care 2010, 14:R133 (13 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective John L Moran, Petra L Graham, Sue Rockliff, Andrew D Bersten Critical Care 2010, 14:R134 (13 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury Qin Lu, Mao Zhang, Cassio Girardi, Belaïd Bouhemad, Jozef Kesecioglu, Jean-Jacques Rouby Critical Care 2010, 14:R135 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Administration of an exogenous surfactant induces significant and prolonged aeration in patients with acute lung injury, but the question of whether a more selective instillation would be beneficial remains unanswered.
	Research Predictors for good functional outcome after neurocritical care Ines C Kiphuth, Peter D Schellinger, Martin Köhrmann, Jürgen Bardutzky, Hannes Lücking, Stephan Kloska, Stefan Schwab, Hagen B Huttner Critical Care 2010, 14:R136 (20 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Positive end-expiratory pressure affects the value of intra-abdominal pressure in acute lung injury/acute respiratory distress syndrome patients: a pilot study Daniel Verzilli, Jean-Michel Constantin, Mustapha Sebbane, Gérald Chanques, Boris Jung, Pierre-François Perrigault, Manu Malbrain, Samir Jaber Critical Care 2010, 14:R137 (21 July 2010) Abstract \| Full text \| PDF \| PubMed
	Research Standardized intensive care unit management in an anhepatic pig model: new standards for analyzing liver support systems Christian Thiel, Karolin Thiel, Alexander Etspueler, Thomas Schenk, Matthias H Morgalla, Alfred Koenigsrainer, Martin Schenk Critical Care 2010, 14:R138 (22 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research APCAP - activated protein C in acute pancreatitis: a double-blind randomized human pilot trial Ville Pettilä, Lea Kyhälä, Marja-Leena Kylänpää, Ari Leppäniemi, Minna Tallgren, Antti Markkola, Pauli Puolakkainen, Heikki Repo, Esko Kemppainen Critical Care 2010, 14:R139 (27 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Cerebral microcirculation is impaired during sepsis: an experimental study Fabio Silvio Taccone, Fuhong Su, Charalampos Pierrakos, Xinrong He, Syril James, Olivier Dewitte, Jean-Louis Vincent, Daniel De Backer Critical Care 2010, 14:R140 (28 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials Hassan Siddiki, Marija Kojicic, Guangxi Li, Murat Yilmaz, Taylor B Thompson, Rolf D Hubmayr, Ognjen Gajic Critical Care 2010, 14:R141 (29 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Early administration of norepinephrine increases cardiac preload and cardiac output in septic patients with life-threatening hypotension Olfa Hamzaoui, Jean-François Georger, Xavier Monnet, Hatem Ksouri, Julien Maizel, Christian Richard, Jean-Louis Teboul Critical Care 2010, 14:R142 (29 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Simvastatin attenuates ventilator-induced lung injury in mice Holger C Müller, Katharina Hellwig, Simone Rosseau, Thomas Tschernig, Andreas Schmiedl, Birgitt Gutbier, Bernd Schmeck, Stefan Hippenstiel, Harm Peters, Lars Morawietz, Norbert Suttorp, Martin Witzenrath Critical Care 2010, 14:R143 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Retrospective agreement and consent to neurocritical care is influenced by functional outcome Ines C Kiphuth, Martin Köhrmann, Joji B Kuramatsu, Christoph Mauer, Lorenz Breuer, Peter D Schellinger, Stefan Schwab, Hagen B Huttner Critical Care 2010, 14:R144 (30 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Identifying predictors for severe disability after ICU treatment would aid physicians in deciding whether to initiate neurocritical care, as rates of retrospective consent are lowest in patients with a poor functional outcome.
	Research Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study Marcel Schouten, Cornelis van't Veer, Joris JTH Roelofs, Marcel Levi, Tom van der Poll Critical Care 2010, 14:R145 (3 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research The impact of delirium on the prediction of in-hospital mortality in intensive care patients Mark van den Boogaard, Sanne AE Peters, Johannes G van der Hoeven, Pieter C Dagnelie, Pieter Leffers, Peter Pickkers, Lisette Schoonhoven Critical Care 2010, 14:R146 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Treatment of hypophosphatemia in the intensive care unit: a review Daniël A Geerse, Alexander J Bindels, Michael A Kuiper, Arnout N Roos, Peter E Spronk, Marcus J Schultz Critical Care 2010, 14:R147 (3 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis Michael Sander, Claudia D Spies, Viktoria Martiny, Christoph Rosenthal, Klaus-Dieter Wernecke, Christian von Heymann Critical Care 2010, 14:R148 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology \| Editor’s summary An association with higher mortality and minor efficiency of tranexamic acid raises questions about the routine high dose administration of the drug in cardiac surgery, according to a retrospective study.
	Research Central venous oxygen saturation and blood lactate levels during cardiopulmonary bypass are associated with outcome after pediatric cardiac surgery Marco Ranucci, Giuseppe Isgrò, Concetta Carlucci, Teresa De La Torre, Stefania Enginoli, Alessandro Frigiola, Surgical and Clinical Outcome REsearch (SCORE) Group Critical Care 2010, 14:R149 (4 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A systematic review of randomized controlled trials exploring the effect of immunomodulative interventions on infection, organ failure, and mortality in trauma patients Nicole E Spruijt, Tjaakje Visser, Luke PH Leenen Critical Care 2010, 14:R150 (5 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The administration of immunoglobulin, interferon-γ or glucan may improve outcomes in trauma patients, for whom inflammatory complications such as multiple organ failure are the most common cause of late death.
	Research Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial Shaman Jhanji, Amanda Vivian-Smith, Susana Lucena-Amaro, David Watson, Charles J Hinds, Rupert M Pearse Critical Care 2010, 14:R151 (10 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Sepsis is a major determinant of outcome in critically ill HIV/AIDS patients André M Japiassú, Rodrigo T Amâncio, Emerson C Mesquita, Denise M Medeiros, Helena B Bernal, Estevão P Nunes, Paula M Luz, Beatriz Grinsztejn, Fernando A Bozza Critical Care 2010, 14:R152 (10 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Severe sepsis is a major cause of mortality for hospitalised HIV/AIDS patients and significantly decreases short- and longer-term survival, finds a study of 88 HIV patients admitted to the intensive care unit.
	Research The use of exenatide in severely burned pediatric patients Gabriel A Mecott, David N Herndon, Gabriela A Kulp, Natasha C Brooks, Ahmed M Al-Mousawi, Robert Kraft, Haidy G Rivero, Felicia N Williams, Ludwik K Branski, Marc G Jeschke Critical Care 2010, 14:R153 (11 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Exenatide was found to be as effective as intensive insulin treatment in decreasing plasma glucose levels, and may represent a novel agent to attenuate hyperglycemia in the critical care setting.
	Research Organ failure and tight glycemic control in the SPRINT study J Geoffrey Chase, Christopher G Pretty, Leesa Pfeifer, Geoffrey M Shaw, Jean-Charles Preiser, Aaron J Le Compte, Jessica Lin, Darren Hewett, Katherine T Moorhead, Thomas Desaive Critical Care 2010, 14:R154 (12 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Who benefits most from mild therapeutic hypothermia in coronary intervention era? A retrospective and propensity-matched study Eisuke Kagawa, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Satoshi Kurisu, Yasuharu Nakama, Kazuoki Dai, Takayuki Otani, Hiroki Ikenaga, Yoshimasa Morimoto, Kentaro Ejiri, Nozomu Oda Critical Care 2010, 14:R155 (16 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Human protein C concentrate in the treatment of purpura fulminans: a retrospective analysis of safety and outcome in 94 pediatric patients Alex Veldman, Doris Fischer, Flora Y Wong, Wolfhart Kreuz, Michael Sasse, Bruno Eberspächer, Ulrich Mansmann, Rudolf Schosser Critical Care 2010, 14:R156 (19 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Interferon-β attenuates lung inflammation following experimental subarachnoid hemorrhage Pieter M Cobelens, Ivo ACW Tiebosch, Rick M Dijkhuizen, Peter H van der Meide, René Zwartbol, Cobi J Heijnen, Jozef Kesecioglu, Walter M van den Bergh Critical Care 2010, 14:R157 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes Carl Ekman, Adam Linder, Per Åkesson, Björn Dahlbäck Critical Care 2010, 14:R158 (23 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection kit Katsunori Yanagihara, Yuko Kitagawa, Masao Tomonaga, Kunihiro Tsukasaki, Shigeru Kohno, Masafumi Seki, Hisashi Sugimoto, Takeshi Shimazu, Osamu Tasaki, Asako Matsushima, Yasuo Ikeda, Shinichiro Okamoto, Naoki Aikawa, Shingo Hori, Hideaki Obara, Akitoshi Ishizaka, Naoki Hasegawa, Junzo Takeda, Shimeru Kamihira, Kazuyuki Sugahara, Seishi Asari, Mitsuru Murata, Yoshio Kobayashi, Hiroyuki Ginba, Yoshinobu Sumiyama, Masaki Kitajima Critical Care 2010, 14:R159 (24 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice Joëlle Rolli, Noureddine Loukili, Sandra Levrand, Nathalie Rosenblatt-Velin, Stéphanie Rignault-Clerc, Bernard Waeber, François Feihl, Pal Pacher, Lucas Liaudet Critical Care 2010, 14:R160 (24 August 2010) Abstract \| Full text \| PDF \| PubMed
	Research Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow Luuk DH Munsterman, Paul WG Elbers, Alaattin Ozdemir, Eric PA van Dongen, Mat van Iterson, Can Ince Critical Care 2010, 14:R161 (25 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter The role for autopsy in the intensive care unit: technological considerations Carlos E Pompilio Critical Care 2010, 14:426 (5 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Another explanation for decreased oxygen consumption in lactic acidosis Viktor Rosival Critical Care 2010, 14:427 (6 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Electrical muscle stimulation for prevention of critical illness polyneuropathy Pablo O Rodriguez, Mariano Setten, Ricardo Valentini Critical Care 2010, 14:428 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter To transfuse or not to transfuse: thinking outside the box Yasser Sakr, Konrad Reinhart Critical Care 2010, 14:431 (27 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Assessment of monocytic HLA-DR expression in ICU patients: analytical issues for multicentric flow cytometry studies Guillaume Monneret, Fabienne Venet, Christian Meisel, Joerg C Schefold Critical Care 2010, 14:432 (27 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Is routine autopsy in the intensive care unit viable? Authors' response Greet De Vlieger, Elien Mahieu, Wouter Meersseman Critical Care 2010, 14:433 (29 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Alpha-2 adrenoceptor agonists and sepsis: improved survival? Luc Quintin Critical Care 2010, 14:429 (29 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Quality of life in patients aged 80 or over after intensive care unit discharge Jacqueline Koeze, Jan G Zijlstra Critical Care 2010, 14:434 (30 July 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Understanding immune dysfunctions in sepsis patients Eduardo López-Collazo, Vanesa Gómez-Piña, Francisco Arnalich Critical Care 2010, 14:435 (10 August 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Heterogeneity in ventilation during positive end-expiratory pressure Mukesh Tripathi, Mamta Pandey Critical Care 2010, 14:436 (17 August 2010) Abstract \| Full text \| PDF \| PubMed
	Letter Lung reaeration after surfactant instillation - caused by surfactant or caused by instillation? Marcus J Schultz Critical Care 2010, 14:437 (20 August 2010) Abstract \| Full text \| PDF \| PubMed

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