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Highly Accessed Review

Year in review 2009: Critical Care - metabolism

Vincent Huberlant and Jean-Charles Preiser*

Author Affiliations

Department of General Intensive Care, University Hospital Centre of Liege, Domaine universitaire du Sart-Tilman, 4000 Liege, Belgium

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Critical Care 2010, 14:238  doi:10.1186/cc9256

Published: 5 November 2010

Abstract

Novel insights into the metabolic alterations of critical illness were published in Critical Care in 2009. The association between early hypoglycaemia/high glycemic variability and poor outcome was confirmed. Improvements in the understanding of the pathophysiological mechanisms of stress hyperglycemia and potential progress in the bedside management of glucose control were presented. With regard to enteral nutrition, some alterations of gastrointestinal physiology were better delineated. The relationship between the achievement of nutritional goals and outcomes was further investigated. Finally, understanding of some critical-illness-related endocrine and neuromuscular disorders improved through new experimental and clinical findings.