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This article is part of the supplement: 30th International Symposium on Intensive Care and Emergency Medicine

Poster presentation

Procalcitonin facing the postoperative culture results after liver transplantation

J Fazakas1*, E Papp1, G Ther1, Z Gallfy1, B Fule1, M Varga1, T Mandli1, S Toth1, J Fazakas2, L Kobori1 and M Arkosy3

  • * Corresponding author: J Fazakas

Author Affiliations

1 Semmelweis University, Budapest, Hungary

2 Bajcsy Zsilinszky Hospital, Budapest, Hungary

3 Soprponi Erzsébet Oktató Kórház, Sopron, Hungary

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Critical Care 2010, 14(Suppl 1):P43  doi:10.1186/cc8275


The electronic version of this article is the complete one and can be found online at: http://ccforum.com/content/14/S1/P43


Published:1 March 2010

© 2010 BioMed Central Ltd.

Introduction

The early inflammatory response after liver transplantation (LTx) could be diagnosed by the simultaneous interpretation of procalcitonin (PCT) levels and culture results. The aim of this prospective, non-interventional study was to evaluate the prognostic significance of the PCT levels in the term of etiology (infection, colonization and non-infectious inflammatory states).

Methods

The PCT measurements and cultures were performed before surgery and on the first five postoperative days in 114 liver transplanted patients. The relationship between the absolute PCT levels (n = 762) and culture results (n = 474) was studied. The patients were divided into two groups according to the infection or colonization with Gram-positive (GP) or Gram-negative (GN) bacteria. Statistical analysis was done with the SPSS program.

Results

In 21 patients negative cultures were associated with PCT elevation (PCT: 3.77 ± 3.22 ng/ml), positive cultures were found in 107 patients, in 58 patients this was colonization (PCT <0.5 ng/ml). There significant differences between the PCT elevation according to the etiology culture (GN, n = 36, PCT: 17.55 ± 11.3 ng/ml; GP, n = 222, PCT: 16.54 ± 6.58 ng/ml; P < 0.02).

Conclusions

In the early phase after liver transplantation, the GP culture occurred more frequently; the GN culture could be associated with higher PCT elevation than those found in case of GP culture.