Critical Care | Volume 15 Issue 2

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	Volume 15 Issue 2
	Comment
	Editorial When pressure does not mean volume? Body mass index may account for the dissociation Vito Fanelli, V Marco Ranieri Critical Care 2011, 15:143 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Greening critical care Martin Chapman, Alison Chapman Critical Care 2011, 15:302 (15 March 2011) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Beyond volutrauma in ARDS: the critical role of lung tissue deformation Guillermo M Albaiceta, Lluis Blanch Critical Care 2011, 15:304 (7 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please! Matthew J Reed, Nazir Lone, Timothy S Walsh Critical Care 2011, 15:126 (1 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Should we abandon manual muscle strength testing in the ICU? Greet Hermans, Rik Gosselink Critical Care 2011, 15:127 (1 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Unplanned extubation in the ICU: a marker of quality assurance of mechanical ventilation Óscar Peñuelas, Fernando Frutos-Vivar, Andrés Esteban Critical Care 2011, 15:128 (8 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Erythropoietin for stroke treatment: dead or alive? Jens Minnerup, Heike Wersching, Wolf-Rüdiger Schäbitz Critical Care 2011, 15:129 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Utile or futile: biomarkers in the ICU Cathrin Balmelli, Beatrice Drexler, Christian Mueller Critical Care 2011, 15:131 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Biological markers and diagnosis of ventilator-associated pneumonia Jean-Yves Fagon Critical Care 2011, 15:130 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary A pseudo-Rumsfeldian approach to pleural effusions in mechanically ventilated patients Jonathan Ball Critical Care 2011, 15:132 (11 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary The need for standardized data reporting for prehospital airway management Daniel P Davis Critical Care 2011, 15:133 (14 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Assessment of fluid responsiveness during increased intra-abdominal pressure: keep the indices, but change the thresholds Benoit Tavernier, Emmanuel Robin Critical Care 2011, 15:134 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis and the broken endothelium Nathan I Shapiro, William C Aird Critical Care 2011, 15:135 (21 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary The role of receptor for advanced glycation endproducts (RAGE) in infection Marieke AD van Zoelen, Ahmed Achouiti, Tom van der Poll Critical Care 2011, 15:208 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Prediction of fluid challenge effect: filling pressure when left ventricular function is abnormal, diastolic volume when left ventricular function is normal Didier Payen Critical Care 2011, 15:139 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Is cytomegalovirus reactivation increasing the mortality of patients with severe sepsis? Andre C Kalil, Diana F Florescu Critical Care 2011, 15:138 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids in severe community-acquired pneumonia: the path we choose depends on where we want to get Jorge IF Salluh, Márcio Soares, Pedro Póvoa Critical Care 2011, 15:137 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Endothelial progenitors in sepsis: vox clamantis in deserto? Michael S Goligorsky Critical Care 2011, 15:142 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Psychological intervention to prevent ICU-related PTSD: who, when and for how long? Rob Hatch, Stuart McKechnie, John Griffiths Critical Care 2011, 15:141 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Magnesium sulfate for aneurysmal subarachnoid hemorrhage: the end of the road or more trials? Mervyn DI Vergouwen Critical Care 2011, 15:140 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Immunostimulation using granulocyte- and granulocyte-macrophage colony stimulating factor in patients with severe sepsis and septic shock Joerg C Schefold Critical Care 2011, 15:136 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Hypothermia, immune suppression and SDD: can we have our cake and eat it? Kees H Polderman Critical Care 2011, 15:144 (31 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Statins: a role in infected critically ill patients? Jonathon Truwit Critical Care 2011, 15:145 (1 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Of mice and men (and sheep, swine etc.): The intriguing hemodynamic and metabolic effects of hydrogen sulfide (H₂S) Katja Wagner, Michael Georgieff, Pierre Asfar, Enrico Calzia, Markus W Knöferl, Peter Radermacher Critical Care 2011, 15:146 (4 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Ultrasound-guided tracheostomy - not for the many, but perhaps the few... or the one Lorraine N Tremblay, Damon C Scales Critical Care 2011, 15:147 (6 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Commentary Out-of-hospital CPR: better outcome for our patients Enrica Golia, Maddalena Piro, Marco Tubaro Critical Care 2011, 15:149 (7 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Why do pulse pressure variations fail to predict the response to fluids in acute respiratory distress syndrome patients ventilated with low tidal volume? Daniel De Backer, Sabino Scolletta Critical Care 2011, 15:150 (12 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary European legislation impedes critical care research and fails to protect patients' rights Ronan MG Berg, Kirsten Møller, Peter Rossel Critical Care 2011, 15:148 (14 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Therapeutic hypothermia post out-of-hospital cardiac arrest - more questions than answers? Richard Lyon Critical Care 2011, 15:151 (15 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Blood transfusion and the lung: first do no harm? Lena M Napolitano Critical Care 2011, 15:152 (18 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Inspiratory muscle training in difficult to wean patients: work it harder, make it better, do it faster, makes us stronger Stefano Nava, Luca Fasano Critical Care 2011, 15:153 (18 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary How deficient are vitamin D deficient critically ill patients? Paul Lee Critical Care 2011, 15:154 (19 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Controversies in acute kidney injury: the 2011 Brussels Roundtable John A Kellum, Claudio Ronco Critical Care 2011, 15:155 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state Joanna Floros, Neal J Thomas Critical Care 2011, 15:156 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Clinical review: Ventilator-induced diaphragmatic dysfunction - human studies confirm animal model findings! Samir Jaber, Boris Jung, Stefan Matecki, Basil J Petrof Critical Care 2011, 15:206 (11 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Optimal dose of continuous renal replacement therapy in acute kidney injury John R Prowle, Antoine Schneider, Rinaldo Bellomo Critical Care 2011, 15:207 (18 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia-inducible factors and the prevention of acute organ injury Samuel N Heyman, Seymour Rosen, Christian Rosenberger Critical Care 2011, 15:209 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Iron deficiency in critically ill patients: highlighting the role of hepcidin Nicholas Heming, Philippe Montravers, Sigismond Lasocki Critical Care 2011, 15:210 (22 March 2011) Full text \| PDF \| PubMed
	Review Heparin-induced thrombocytopenia in the ICU: an overview Yasser Sakr Critical Care 2011, 15:211 (22 March 2011) Full text \| PDF \| PubMed \| 1 comment
	Review Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS? Gerard Curley, Mairead Hayes, John G Laffey Critical Care 2011, 15:212 (22 March 2011) Full text \| PDF \| PubMed
	Review The microcirculation of the critically ill pediatric patient Anke PC Top, Robert C Tasker, Can Ince Critical Care 2011, 15:213 (22 March 2011) Full text \| PDF \| PubMed
	Review Cardiac output monitoring: an integrative perspective Jamal A Alhashemi, Maurizio Cecconi, Christoph K Hofer Critical Care 2011, 15:214 (22 March 2011) Full text \| PDF \| PubMed
	Review New treatment options against gram-negative organisms Matteo Bassetti, Francesca Ginocchio, Malgorzata Mikulska Critical Care 2011, 15:215 (22 March 2011) Full text \| PDF \| PubMed
	Review Access block and emergency department overcrowding Roberto Forero, Sally McCarthy, Ken Hillman Critical Care 2011, 15:216 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Triage of high-risk surgical patients for intensive care Julia B Sobol, Hannah Wunsch Critical Care 2011, 15:217 (22 March 2011) Full text \| PDF \| PubMed
	Review The effect of light on critical illness Ricardo Castro, Derek C Angus, Matt R Rosengart Critical Care 2011, 15:218 (22 March 2011) Full text \| PDF \| PubMed
	Review Clinical review: Ketones and brain injury Hayden White, Balasubramanian Venkatesh Critical Care 2011, 15:219 (6 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Review Clinical review: Adiponectin biology and its role in inflammation and critical illness Katherine Robinson, John Prins, Bala Venkatesh Critical Care 2011, 15:221 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Intrapericardial fibrinolysis in management of purulent pericarditis Pascal Augustin, Mathieu Desmard, Pierre Mordant, Sigismond Lasocki, Jean-Michel Maury, Nicholas Heming, Philippe Montravers Critical Care 2011, 15:220 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity Benny Sørensen, Donat R Spahn, Petra Innerhofer, Michael Spannagl, Rolf Rossaint Critical Care 2011, 15:409 (18 March 2011) Full text \| PDF \| PubMed
	Correction Correction: Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials Hassan Siddiki, Marija Kojicic, Guangxi Li, Murat Yilmaz, Taylor B Thompson, Rolf D Hubmayr, Ognjen Gajic Critical Care 2011, 15:410 (12 April 2011) Full text \| PDF \| PubMed
	Correction Correction: Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients Adriano Peris, Manuela Bonizzoli, Dario Iozzelli, Maria Migliaccio, Giovanni Zagli, Alberto Bacchereti, Marta Debolini, Elisetta Vannini, Massimo Solaro, Ilaria Balzi, Elisa Bendoni, Ilaria Bacchi, Monica Trevisan, Valtere Giovannini, Laura Belloni Critical Care 2011, 15:418 (18 April 2011) Full text \| PDF \| PubMed
	Book report Critical Care Handbook of the Massachusetts General Hospital Djillali Annane Critical Care 2011, 15:303 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis Alexandra Heininger, Helene Haeberle, Imma Fischer, Robert Beck, Reimer Riessen, Frank Rohde, Christoph Meisner, Gerhard Jahn, Alfred Koenigsrainer, Klaus Unertl, Klaus Hamprecht Critical Care 2011, 15:R77 (1 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients Stuart McGrane, Timothy D Girard, Jennifer L Thompson, Ayumi K Shintani, Alison Woodworth, E Wesley Ely, Pratik P Pandharipande Critical Care 2011, 15:R78 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia Mi Kyong Joung, Jeong-a Lee, Soo-youn Moon, Hae Cheong, Eun-Jeong Joo, Young-Eun Ha, Kyung Sohn, Seung Chung, Gee Suh, Doo Chung, Jae-Hoon Song, Kyong Peck Critical Care 2011, 15:R79 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection Gernot Beutel, Olaf Wiesner, Matthias Eder, Carsten Hafer, Andrea S Schneider, Jan T Kielstein, Christian Kühn, Albert Heim, Tina Ganzenmüller, Hans-Heinrich Kreipe, Axel Haverich, Andreas Tecklenburg, Arnold Ganser, Tobias Welte, Marius M Hoeper Critical Care 2011, 15:R80 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of window rooms on critically ill patients with subarachnoid hemorrhage admitted to intensive care Hannah Wunsch, Hayley Gershengorn, Stephan A Mayer, Jan Claassen Critical Care 2011, 15:R81 (3 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Receiving intensive care unit (ICU) treatment in a room with natural light from a window had no effect on short- or long-term outcome in patients with a brain injury
	Research Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study Jens Altrichter, Martin Sauer, Katharina Kaftan, Thomas Birken, Doris Gloger, Martin Gloger, Jörg Henschel, Heiko Hickstein, Ernst Klar, Sebastian Koball, Annette Pertschy, Gabriele Nöldge-Schomburg, Dierk A Vagts, Steffen R Mitzner Critical Care 2011, 15:R82 (3 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy Herbert Schöchl, Ulrike Nienaber, Marc Maegele, Gerald Hochleitner, Florian Primavesi, Beatrice Steitz, Christian Arndt, Alexander Hanke, Wolfgang Voelckel, Cristina Solomon Critical Care 2011, 15:R83 (4 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial A Daniel Martin, Barbara K Smith, Paul D Davenport, Eloise Harman, Ricardo J Gonzalez-Rothi, Maher Baz, A Joseph Layon, Michael J Banner, Lawrence J Caruso, Harsha Deoghare, Tseng-Tien Huang, Andrea Gabrielli Critical Care 2011, 15:R84 (7 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome Karim Lakhal, Stephan Ehrmann, Dalila Benzekri-Lefèvre, Isabelle Runge, Annick Legras, Pierre-François Dequin, Emmanuelle Mercier, Michel Wolff, Bernard Régnier, Thierry Boulain Critical Care 2011, 15:R85 (7 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status Todd W Rice, Lorraine B Ware, Edward F Haponik, Caroline Chiles, Arthur P Wheeler, Gordon R Bernard, Jay S Steingrub, R Duncan Hite, Michael A Matthay, Patrick Wright, E Wesley Ely, the NIH NHLBI ARDS Network Critical Care 2011, 15:R86 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Preadmission beta-blocker use and 30-day mortality among patients in intensive care: a cohort study Steffen Christensen, Martin Johansen, Else Tønnesen, Anders Larsson, Lars Pedersen, Stanley Lemeshow, Henrik Sørensen Critical Care 2011, 15:R87 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study Frank Bloos, John C Marshall, Richard P Dellinger, Jean-Louis Vincent, Guillermo Gutierrez, Emanuel Rivers, Robert A Balk, Pierre-Francois Laterre, Derek C Angus, Konrad Reinhart, Frank M Brunkhorst Critical Care 2011, 15:R88 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Activated protein C in septic shock: a propensity-matched analysis Farid Sadaka, Jacklyn O'Brien, Matthew Migneron, Julie Stortz, Alexander Vanston, Robert W Taylor Critical Care 2011, 15:R89 (8 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest Rinaldo Bellomo, Michael Bailey, Glenn M Eastwood, Alistair Nichol, David Pilcher, Graeme K Hart, Michael C Reade, Moritoki Egi, D James Cooper, the Study of Oxygen in Critical Care (SOCC) Group Critical Care 2011, 15:R90 (8 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute respiratory failure in kidney transplant recipients: a multicenter study Emmanuel Canet, David Osman, Jérome Lambert, Christophe Guitton, Anne-Elisabeth Heng, Laurent Argaud, Kada Klouche, Georges Mourad, Christophe Legendre, Jean-François Timsit, Eric Rondeau, Maryvonne Hourmant, Antoine Durrbach, Denis Glotz, Bertrand Souweine, Benoît Schlemmer, Elie Azoulay Critical Care 2011, 15:R91 (8 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research The acute management of trauma hemorrhage: a systematic review of randomized controlled trials Nicola Curry, Sally Hopewell, Carolyn Dorée, Chris Hyde, Karim Brohi, Simon Stanworth Critical Care 2011, 15:R92 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute and critically ill peripartum cardiomyopathy and 'bridge to' therapeutic options: a single center experience with intra-aortic balloon pump, extra corporeal membrane oxygenation and continuous-flow left ventricular assist devices Sofie Gevaert, Yves Van Belleghem, Stefaan Bouchez, Ingrid Herck, Filip De Somer, Yasmina De Block, Fiona Tromp, Els Vandecasteele, Floor Martens, Michel De Pauw Critical Care 2011, 15:R93 (10 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD) Susann A Patschan, Daniel Patschan, Johanna Temme, Peter Korsten, Johannes T Wessels, Michael Koziolek, Elvira Henze, Gerhard A Müller Critical Care 2011, 15:R94 (11 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Assessment of disease-severity scoring systems for patients with sepsis in general internal medicine departments Nesrin O Ghanem-Zoubi, Moshe Vardi, Arie Laor, Gabriel Weber, Haim Bitterman Critical Care 2011, 15:R95 (14 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial Silvia Fernández-Serrano, Jordi Dorca, Carolina Garcia-Vidal, Núria Fernández-Sabé, Jordi Carratalà, Ana Fernández-Agüera, Mercè Corominas, Susana Padrones, Francesc Gudiol, Frederic Manresa Critical Care 2011, 15:R96 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis Leonardo Lorente, María M Martín, Nerea Varo, Juan María Borreguero-León, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Eduardo Pastor, Felipe Belmonte, Josune Orbe, José A Rodríguez, Eduardo Gómez-Melini, José M Ferrer-Agüero, José Ferreres, María C LLimiñana, José A Páramo Critical Care 2011, 15:R97 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials Daren K Heyland, John Muscedere, John Drover, Xuran Jiang, Andrew G Day, the Canadian Critical Care Trials Group Critical Care 2011, 15:R98 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients Caroline Guignant, Alain Lepape, Xin Huang, Hakim Kherouf, Laure Denis, Françoise Poitevin, Christophe Malcus, Aurélie Chéron, Bernard Allaouchiche, François Gueyffier, Alfred Ayala, Guillaume Monneret, Fabienne Venet Critical Care 2011, 15:R99 (21 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality John R Prowle, Jorge E Echeverri, E Valentina Ligabo, Norelle Sherry, Gopal C Taori, Timothy M Crozier, Graeme K Hart, Tony M Korman, Barrie C Mayall, Paul DR Johnson, Rinaldo Bellomo Critical Care 2011, 15:R100 (21 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest Moritz Haugk, Christoph Testori, Fritz Sterz, Maximilian Uranitsch, Michael Holzer, Wilhelm Behringer, Harald Herkner, the Time to Target Temperature Study Group Critical Care 2011, 15:R101 (25 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit Nazir I Lone, Timothy S Walsh Critical Care 2011, 15:R102 (27 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The prognostic value of markers of right ventricular dysfunction in pulmonary embolism: a meta-analysis Guillaume Coutance, Emmanuelle Cauderlier, Javed Ehtisham, Michèle Hamon, Martial Hamon Critical Care 2011, 15:R103 (28 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study Karin Amrein, Harald Sourij, Gerit Wagner, Alexander Holl, Thomas R Pieber, Karl Heinz Smolle, Tatjana Stojakovic, Christian Schnedl, Harald Dobnig Critical Care 2011, 15:R104 (28 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Functional status and quality of life 12 months after discharge from a medical ICU in healthy elderly patients: a prospective observational study Emilio Sacanella, Joan Manel Pérez-Castejón, Josep Maria Nicolás, Ferran Masanés, Marga Navarro, Pedro Castro, Alfonso López-Soto Critical Care 2011, 15:R105 (28 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Extremes of weight centile are associated with increased risk of mortality in pediatric intensive care Andrew Numa, John McAweeney, Gary Williams, John Awad, Hari Ravindranathan Critical Care 2011, 15:R106 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Life expectancies and incidence rates of patients under prolonged mechanical ventilation: a population-based study during 1998 to 2007 in Taiwan Mei-Chuan Hung, Hsin-Ming Lu, Likwang Chen, Fu-Chang Hu, Soa-Yu Chan, Yuan-Horng Yan, Po-Sheng Fan, Ming-Shian Lin, Cheng-Ren Chen, Lu-Cheng Kuo, Chong-Jen Yu, Jung-Der Wang Critical Care 2011, 15:R107 (1 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time Simon J Stanworth, Timothy S Walsh, Robin J Prescott, Robert J Lee, Douglas M Watson, Duncan Wyncoll, the Intensive Care Study of Coagulopathy (ISOC) investigators Critical Care 2011, 15:R108 (5 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary There is substantial variation in clinical use of fresh frozen plasma in terms of indication and dosage, with a high proportion of transfusions being of uncertain and unproven clinical benefit.
	Research Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients Alexander Koch, Lutz Hamann, Matthias Schott, Olaf Boehm, Dirk Grotemeyer, Muhammed Kurt, Carsten Schwenke, Ralf R Schumann, Stefan R Bornstein, Kai Zacharowski Critical Care 2011, 15:R109 (5 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Activation of factor VII-activating protease in human inflammation: a sensor for cell death Femke Stephan, Jan A Hazelzet, Ingrid Bulder, Marja A Boermeester, JW van Till, Tom van der Poll, Walter A Wuillemin, Lucien A Aarden, Sacha Zeerleder Critical Care 2011, 15:R110 (5 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research An evidence-based recommendation on bed head elevation for mechanically ventilated patients Barbara S Niël-Weise, Petra Gastmeier, Axel Kola, Ralf P Vonberg, Jan C Wille, Peterhans J van den Broek, the Bed Head Elevation Study Group Critical Care 2011, 15:R111 (11 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa Catherine Kaminski, Jean-François Timsit, Yohann Dubois, Jean-Ralph Zahar, Maïté Garrouste-Orgeas, Aurélien Vesin, Elie Azoulay, Céline Feger, Anne-Sylvie Dumenil, Christophe Adrie, Yves Cohen, Bernard Allaouchiche, the OUTCOMEREA study group Critical Care 2011, 15:R112 (11 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation Sang Hwang, Ji-Eun Kim, Kyou-Sup Han, Hyun Kim Critical Care 2011, 15:R113 (14 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting Gregor Prosen, Petra Klemen, Matej Strnad, Štefek Grmec Critical Care 2011, 15:R114 (14 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Soluble triggering receptor on myeloid cells-1 is expressed in the course of non-infectious inflammation after traumatic lung contusion: a prospective cohort study Tobias M Bingold, Barbara Pullmann, Sven Sartorius, Emanuel V Geiger, Ingo Marzi, Kai Zacharowski, Heimo Wissing, Bertram Scheller Critical Care 2011, 15:R115 (15 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Age of red blood cells and mortality in the critically ill Ville Pettilä, Andrew J Westbrook, Alistair D Nichol, Michael J Bailey, Erica M Wood, Gillian Syres, Louise E Phillips, Alison Street, Craig French, Lynnette Murray, Neil Orford, John D Santamaria, Rinaldo Bellomo, David J Cooper, the Blood Observational Study Investigators for the ANZICS Clinical Trials Group Critical Care 2011, 15:R116 (15 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research High-dose tranexamic acid reduces blood loss in postpartum haemorrhage Anne-Sophie Ducloy-Bouthors, Brigitte Jude, Alain Duhamel, Françoise Broisin, Cyril Huissoud, Hawa Keita-Meyer, Laurent Mandelbrot, Nadia Tillouche, Sylvie Fontaine, Françoise Le Goueff, Sandrine Depret-Mosser, Benoit Vallet, The EXADELI Study Group, Sophie Susen Critical Care 2011, 15:R117 (15 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Research Transpulmonary thermodilution for hemodynamic measurements in severely burned children Ludwik K Branski, David N Herndon, Jaron F Byrd, Michael P Kinsky, Jong O Lee, Shawn P Fagan, Marc G Jeschke Critical Care 2011, 15:R118 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter Respiratory support withdrawal in intensive care units: international differences stressed and straightened! Jelle L Epker, Yorick J de Groot, Erwin J Kompanje Critical Care 2011, 15:405 (2 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Use of minimally invasive hemodynamic monitoring to assess dynamic changes in cardiac output at the bedside Michael R Pinsky Critical Care 2011, 15:406 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter How did you sleep in the ICU? Laetitia Franck, Jean-Pierre Tourtier, Nicolas Libert, Laurent Grasser, Yves Auroy Critical Care 2011, 15:408 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Recombinant factor VIIa and factor VIII treatment for acquired factor VIII deficiency: a case of repeated thrombotic endotracheal occlusion in a mechanically ventilated patient Stefan Lauer, Martin Westphal, Lars G Fischer, Andreas Meißner, Hugo Van Aken, Hendrik Freise Critical Care 2011, 15:407 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Selective digestive decontamination is superior to selective oropharyngeal decontamination Luciano Silvestri, Nia Taylor, Durk F Zandstra, Hendrick KF van Saene Critical Care 2011, 15:411 (18 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Cytomegalovirus infection monitored by quantitative real-time PCR in critically ill patients Julien Bordes, Tiphaine Gaillard, Jérôme Maslin, Pierre Esnault, Philippe Goutorbe, Patrick Brisou Critical Care 2011, 15:412 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Early corticosteroid treatment for severe pneumonia caused by 2009 H1N1 influenza virus Hong-Ryang Kil, Jae-Ho Lee, Kyung-Yil Lee, Jung-Woo Rhim, You-Sook Youn, Jin-Han Kang Critical Care 2011, 15:413 (22 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Pulse pressure variation, stroke volume variation and dynamic arterial elastance Raphael Giraud, Nils Siegenthaler, Karim Bendjelid Critical Care 2011, 15:414 (23 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Does renal replacement therapy increase mortality in the ICU? David Pestaña Critical Care 2011, 15:415 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Licorice consumption-associated thunderclap headache: posterior reversible encephalopathy syndrome or subarachnoid hemorrhage? Hongliang Zhang, Xiao-Feng Wang, Jiang Wu Critical Care 2011, 15:416 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Microsphere contrast echocardiography in the critical care complex David G Platts, John F Fraser Critical Care 2011, 15:417 (6 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Distinction between induction and maintenance dosing in continuous renal replacement therapy Graeme MacLaren Critical Care 2011, 15:419 (26 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Older patients in the ICU: a cautious analysis of epidemiologic data is required Thomas Fassier, Antoine Duclos Critical Care 2011, 15:421 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Diagnosis of invasive bronchial-pulmonary aspergillosis in patients with chronic obstructive respiratory diseases Pierre Bulpa, Alain Dive Critical Care 2011, 15:420 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter In critically ill patients the procalcitonin level can be misleading Jacqueline Koeze, MG Ron Hendrix, Frank AJTM van den Bergh, René ML Brouwer, Jan G Zijlstra Critical Care 2011, 15:422 (28 April 2011) Abstract \| Full text \| PDF \| PubMed

	Volume 15 Issue 2
	Comment
	Editorial When pressure does not mean volume? Body mass index may account for the dissociation Vito Fanelli, V Marco Ranieri Critical Care 2011, 15:143 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Greening critical care Martin Chapman, Alison Chapman Critical Care 2011, 15:302 (15 March 2011) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Beyond volutrauma in ARDS: the critical role of lung tissue deformation Guillermo M Albaiceta, Lluis Blanch Critical Care 2011, 15:304 (7 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please! Matthew J Reed, Nazir Lone, Timothy S Walsh Critical Care 2011, 15:126 (1 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Should we abandon manual muscle strength testing in the ICU? Greet Hermans, Rik Gosselink Critical Care 2011, 15:127 (1 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Unplanned extubation in the ICU: a marker of quality assurance of mechanical ventilation Óscar Peñuelas, Fernando Frutos-Vivar, Andrés Esteban Critical Care 2011, 15:128 (8 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Erythropoietin for stroke treatment: dead or alive? Jens Minnerup, Heike Wersching, Wolf-Rüdiger Schäbitz Critical Care 2011, 15:129 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Utile or futile: biomarkers in the ICU Cathrin Balmelli, Beatrice Drexler, Christian Mueller Critical Care 2011, 15:131 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Biological markers and diagnosis of ventilator-associated pneumonia Jean-Yves Fagon Critical Care 2011, 15:130 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary A pseudo-Rumsfeldian approach to pleural effusions in mechanically ventilated patients Jonathan Ball Critical Care 2011, 15:132 (11 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary The need for standardized data reporting for prehospital airway management Daniel P Davis Critical Care 2011, 15:133 (14 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Assessment of fluid responsiveness during increased intra-abdominal pressure: keep the indices, but change the thresholds Benoit Tavernier, Emmanuel Robin Critical Care 2011, 15:134 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Sepsis and the broken endothelium Nathan I Shapiro, William C Aird Critical Care 2011, 15:135 (21 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary The role of receptor for advanced glycation endproducts (RAGE) in infection Marieke AD van Zoelen, Ahmed Achouiti, Tom van der Poll Critical Care 2011, 15:208 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Prediction of fluid challenge effect: filling pressure when left ventricular function is abnormal, diastolic volume when left ventricular function is normal Didier Payen Critical Care 2011, 15:139 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Is cytomegalovirus reactivation increasing the mortality of patients with severe sepsis? Andre C Kalil, Diana F Florescu Critical Care 2011, 15:138 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Corticosteroids in severe community-acquired pneumonia: the path we choose depends on where we want to get Jorge IF Salluh, Márcio Soares, Pedro Póvoa Critical Care 2011, 15:137 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Endothelial progenitors in sepsis: vox clamantis in deserto? Michael S Goligorsky Critical Care 2011, 15:142 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Psychological intervention to prevent ICU-related PTSD: who, when and for how long? Rob Hatch, Stuart McKechnie, John Griffiths Critical Care 2011, 15:141 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Magnesium sulfate for aneurysmal subarachnoid hemorrhage: the end of the road or more trials? Mervyn DI Vergouwen Critical Care 2011, 15:140 (25 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Immunostimulation using granulocyte- and granulocyte-macrophage colony stimulating factor in patients with severe sepsis and septic shock Joerg C Schefold Critical Care 2011, 15:136 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Hypothermia, immune suppression and SDD: can we have our cake and eat it? Kees H Polderman Critical Care 2011, 15:144 (31 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Statins: a role in infected critically ill patients? Jonathon Truwit Critical Care 2011, 15:145 (1 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Of mice and men (and sheep, swine etc.): The intriguing hemodynamic and metabolic effects of hydrogen sulfide (H₂S) Katja Wagner, Michael Georgieff, Pierre Asfar, Enrico Calzia, Markus W Knöferl, Peter Radermacher Critical Care 2011, 15:146 (4 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Ultrasound-guided tracheostomy - not for the many, but perhaps the few... or the one Lorraine N Tremblay, Damon C Scales Critical Care 2011, 15:147 (6 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Commentary Out-of-hospital CPR: better outcome for our patients Enrica Golia, Maddalena Piro, Marco Tubaro Critical Care 2011, 15:149 (7 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Why do pulse pressure variations fail to predict the response to fluids in acute respiratory distress syndrome patients ventilated with low tidal volume? Daniel De Backer, Sabino Scolletta Critical Care 2011, 15:150 (12 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary European legislation impedes critical care research and fails to protect patients' rights Ronan MG Berg, Kirsten Møller, Peter Rossel Critical Care 2011, 15:148 (14 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Therapeutic hypothermia post out-of-hospital cardiac arrest - more questions than answers? Richard Lyon Critical Care 2011, 15:151 (15 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Blood transfusion and the lung: first do no harm? Lena M Napolitano Critical Care 2011, 15:152 (18 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Inspiratory muscle training in difficult to wean patients: work it harder, make it better, do it faster, makes us stronger Stefano Nava, Luca Fasano Critical Care 2011, 15:153 (18 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary How deficient are vitamin D deficient critically ill patients? Paul Lee Critical Care 2011, 15:154 (19 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Controversies in acute kidney injury: the 2011 Brussels Roundtable John A Kellum, Claudio Ronco Critical Care 2011, 15:155 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Surfactant protein genetics in community-acquired pneumonia: balancing the host inflammatory state Joanna Floros, Neal J Thomas Critical Care 2011, 15:156 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Clinical review: Ventilator-induced diaphragmatic dysfunction - human studies confirm animal model findings! Samir Jaber, Boris Jung, Stefan Matecki, Basil J Petrof Critical Care 2011, 15:206 (11 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Optimal dose of continuous renal replacement therapy in acute kidney injury John R Prowle, Antoine Schneider, Rinaldo Bellomo Critical Care 2011, 15:207 (18 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Hypoxia-inducible factors and the prevention of acute organ injury Samuel N Heyman, Seymour Rosen, Christian Rosenberger Critical Care 2011, 15:209 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Iron deficiency in critically ill patients: highlighting the role of hepcidin Nicholas Heming, Philippe Montravers, Sigismond Lasocki Critical Care 2011, 15:210 (22 March 2011) Full text \| PDF \| PubMed
	Review Heparin-induced thrombocytopenia in the ICU: an overview Yasser Sakr Critical Care 2011, 15:211 (22 March 2011) Full text \| PDF \| PubMed \| 1 comment
	Review Can 'permissive' hypercapnia modulate the severity of sepsis-induced ALI/ARDS? Gerard Curley, Mairead Hayes, John G Laffey Critical Care 2011, 15:212 (22 March 2011) Full text \| PDF \| PubMed
	Review The microcirculation of the critically ill pediatric patient Anke PC Top, Robert C Tasker, Can Ince Critical Care 2011, 15:213 (22 March 2011) Full text \| PDF \| PubMed
	Review Cardiac output monitoring: an integrative perspective Jamal A Alhashemi, Maurizio Cecconi, Christoph K Hofer Critical Care 2011, 15:214 (22 March 2011) Full text \| PDF \| PubMed
	Review New treatment options against gram-negative organisms Matteo Bassetti, Francesca Ginocchio, Malgorzata Mikulska Critical Care 2011, 15:215 (22 March 2011) Full text \| PDF \| PubMed
	Review Access block and emergency department overcrowding Roberto Forero, Sally McCarthy, Ken Hillman Critical Care 2011, 15:216 (22 March 2011) Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Triage of high-risk surgical patients for intensive care Julia B Sobol, Hannah Wunsch Critical Care 2011, 15:217 (22 March 2011) Full text \| PDF \| PubMed
	Review The effect of light on critical illness Ricardo Castro, Derek C Angus, Matt R Rosengart Critical Care 2011, 15:218 (22 March 2011) Full text \| PDF \| PubMed
	Review Clinical review: Ketones and brain injury Hayden White, Balasubramanian Venkatesh Critical Care 2011, 15:219 (6 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Review Clinical review: Adiponectin biology and its role in inflammation and critical illness Katherine Robinson, John Prins, Bala Venkatesh Critical Care 2011, 15:221 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Intrapericardial fibrinolysis in management of purulent pericarditis Pascal Augustin, Mathieu Desmard, Pierre Mordant, Sigismond Lasocki, Jean-Michel Maury, Nicholas Heming, Philippe Montravers Critical Care 2011, 15:220 (20 April 2011) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity Benny Sørensen, Donat R Spahn, Petra Innerhofer, Michael Spannagl, Rolf Rossaint Critical Care 2011, 15:409 (18 March 2011) Full text \| PDF \| PubMed
	Correction Correction: Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials Hassan Siddiki, Marija Kojicic, Guangxi Li, Murat Yilmaz, Taylor B Thompson, Rolf D Hubmayr, Ognjen Gajic Critical Care 2011, 15:410 (12 April 2011) Full text \| PDF \| PubMed
	Correction Correction: Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients Adriano Peris, Manuela Bonizzoli, Dario Iozzelli, Maria Migliaccio, Giovanni Zagli, Alberto Bacchereti, Marta Debolini, Elisetta Vannini, Massimo Solaro, Ilaria Balzi, Elisa Bendoni, Ilaria Bacchi, Monica Trevisan, Valtere Giovannini, Laura Belloni Critical Care 2011, 15:418 (18 April 2011) Full text \| PDF \| PubMed
	Book report Critical Care Handbook of the Massachusetts General Hospital Djillali Annane Critical Care 2011, 15:303 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis Alexandra Heininger, Helene Haeberle, Imma Fischer, Robert Beck, Reimer Riessen, Frank Rohde, Christoph Meisner, Gerhard Jahn, Alfred Koenigsrainer, Klaus Unertl, Klaus Hamprecht Critical Care 2011, 15:R77 (1 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients Stuart McGrane, Timothy D Girard, Jennifer L Thompson, Ayumi K Shintani, Alison Woodworth, E Wesley Ely, Pratik P Pandharipande Critical Care 2011, 15:R78 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia Mi Kyong Joung, Jeong-a Lee, Soo-youn Moon, Hae Cheong, Eun-Jeong Joo, Young-Eun Ha, Kyung Sohn, Seung Chung, Gee Suh, Doo Chung, Jae-Hoon Song, Kyong Peck Critical Care 2011, 15:R79 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection Gernot Beutel, Olaf Wiesner, Matthias Eder, Carsten Hafer, Andrea S Schneider, Jan T Kielstein, Christian Kühn, Albert Heim, Tina Ganzenmüller, Hans-Heinrich Kreipe, Axel Haverich, Andreas Tecklenburg, Arnold Ganser, Tobias Welte, Marius M Hoeper Critical Care 2011, 15:R80 (2 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of window rooms on critically ill patients with subarachnoid hemorrhage admitted to intensive care Hannah Wunsch, Hayley Gershengorn, Stephan A Mayer, Jan Claassen Critical Care 2011, 15:R81 (3 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Receiving intensive care unit (ICU) treatment in a room with natural light from a window had no effect on short- or long-term outcome in patients with a brain injury
	Research Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study Jens Altrichter, Martin Sauer, Katharina Kaftan, Thomas Birken, Doris Gloger, Martin Gloger, Jörg Henschel, Heiko Hickstein, Ernst Klar, Sebastian Koball, Annette Pertschy, Gabriele Nöldge-Schomburg, Dierk A Vagts, Steffen R Mitzner Critical Care 2011, 15:R82 (3 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy Herbert Schöchl, Ulrike Nienaber, Marc Maegele, Gerald Hochleitner, Florian Primavesi, Beatrice Steitz, Christian Arndt, Alexander Hanke, Wolfgang Voelckel, Cristina Solomon Critical Care 2011, 15:R83 (4 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial A Daniel Martin, Barbara K Smith, Paul D Davenport, Eloise Harman, Ricardo J Gonzalez-Rothi, Maher Baz, A Joseph Layon, Michael J Banner, Lawrence J Caruso, Harsha Deoghare, Tseng-Tien Huang, Andrea Gabrielli Critical Care 2011, 15:R84 (7 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome Karim Lakhal, Stephan Ehrmann, Dalila Benzekri-Lefèvre, Isabelle Runge, Annick Legras, Pierre-François Dequin, Emmanuelle Mercier, Michel Wolff, Bernard Régnier, Thierry Boulain Critical Care 2011, 15:R85 (7 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status Todd W Rice, Lorraine B Ware, Edward F Haponik, Caroline Chiles, Arthur P Wheeler, Gordon R Bernard, Jay S Steingrub, R Duncan Hite, Michael A Matthay, Patrick Wright, E Wesley Ely, the NIH NHLBI ARDS Network Critical Care 2011, 15:R86 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Preadmission beta-blocker use and 30-day mortality among patients in intensive care: a cohort study Steffen Christensen, Martin Johansen, Else Tønnesen, Anders Larsson, Lars Pedersen, Stanley Lemeshow, Henrik Sørensen Critical Care 2011, 15:R87 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study Frank Bloos, John C Marshall, Richard P Dellinger, Jean-Louis Vincent, Guillermo Gutierrez, Emanuel Rivers, Robert A Balk, Pierre-Francois Laterre, Derek C Angus, Konrad Reinhart, Frank M Brunkhorst Critical Care 2011, 15:R88 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Activated protein C in septic shock: a propensity-matched analysis Farid Sadaka, Jacklyn O'Brien, Matthew Migneron, Julie Stortz, Alexander Vanston, Robert W Taylor Critical Care 2011, 15:R89 (8 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest Rinaldo Bellomo, Michael Bailey, Glenn M Eastwood, Alistair Nichol, David Pilcher, Graeme K Hart, Michael C Reade, Moritoki Egi, D James Cooper, the Study of Oxygen in Critical Care (SOCC) Group Critical Care 2011, 15:R90 (8 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute respiratory failure in kidney transplant recipients: a multicenter study Emmanuel Canet, David Osman, Jérome Lambert, Christophe Guitton, Anne-Elisabeth Heng, Laurent Argaud, Kada Klouche, Georges Mourad, Christophe Legendre, Jean-François Timsit, Eric Rondeau, Maryvonne Hourmant, Antoine Durrbach, Denis Glotz, Bertrand Souweine, Benoît Schlemmer, Elie Azoulay Critical Care 2011, 15:R91 (8 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research The acute management of trauma hemorrhage: a systematic review of randomized controlled trials Nicola Curry, Sally Hopewell, Carolyn Dorée, Chris Hyde, Karim Brohi, Simon Stanworth Critical Care 2011, 15:R92 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute and critically ill peripartum cardiomyopathy and 'bridge to' therapeutic options: a single center experience with intra-aortic balloon pump, extra corporeal membrane oxygenation and continuous-flow left ventricular assist devices Sofie Gevaert, Yves Van Belleghem, Stefaan Bouchez, Ingrid Herck, Filip De Somer, Yasmina De Block, Fiona Tromp, Els Vandecasteele, Floor Martens, Michel De Pauw Critical Care 2011, 15:R93 (10 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD) Susann A Patschan, Daniel Patschan, Johanna Temme, Peter Korsten, Johannes T Wessels, Michael Koziolek, Elvira Henze, Gerhard A Müller Critical Care 2011, 15:R94 (11 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Assessment of disease-severity scoring systems for patients with sepsis in general internal medicine departments Nesrin O Ghanem-Zoubi, Moshe Vardi, Arie Laor, Gabriel Weber, Haim Bitterman Critical Care 2011, 15:R95 (14 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial Silvia Fernández-Serrano, Jordi Dorca, Carolina Garcia-Vidal, Núria Fernández-Sabé, Jordi Carratalà, Ana Fernández-Agüera, Mercè Corominas, Susana Padrones, Francesc Gudiol, Frederic Manresa Critical Care 2011, 15:R96 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis Leonardo Lorente, María M Martín, Nerea Varo, Juan María Borreguero-León, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Eduardo Pastor, Felipe Belmonte, Josune Orbe, José A Rodríguez, Eduardo Gómez-Melini, José M Ferrer-Agüero, José Ferreres, María C LLimiñana, José A Páramo Critical Care 2011, 15:R97 (15 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials Daren K Heyland, John Muscedere, John Drover, Xuran Jiang, Andrew G Day, the Canadian Critical Care Trials Group Critical Care 2011, 15:R98 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients Caroline Guignant, Alain Lepape, Xin Huang, Hakim Kherouf, Laure Denis, Françoise Poitevin, Christophe Malcus, Aurélie Chéron, Bernard Allaouchiche, François Gueyffier, Alfred Ayala, Guillaume Monneret, Fabienne Venet Critical Care 2011, 15:R99 (21 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality John R Prowle, Jorge E Echeverri, E Valentina Ligabo, Norelle Sherry, Gopal C Taori, Timothy M Crozier, Graeme K Hart, Tony M Korman, Barrie C Mayall, Paul DR Johnson, Rinaldo Bellomo Critical Care 2011, 15:R100 (21 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Relationship between time to target temperature and outcome in patients treated with therapeutic hypothermia after cardiac arrest Moritz Haugk, Christoph Testori, Fritz Sterz, Maximilian Uranitsch, Michael Holzer, Wilhelm Behringer, Harald Herkner, the Time to Target Temperature Study Group Critical Care 2011, 15:R101 (25 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit Nazir I Lone, Timothy S Walsh Critical Care 2011, 15:R102 (27 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The prognostic value of markers of right ventricular dysfunction in pulmonary embolism: a meta-analysis Guillaume Coutance, Emmanuelle Cauderlier, Javed Ehtisham, Michèle Hamon, Martial Hamon Critical Care 2011, 15:R103 (28 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study Karin Amrein, Harald Sourij, Gerit Wagner, Alexander Holl, Thomas R Pieber, Karl Heinz Smolle, Tatjana Stojakovic, Christian Schnedl, Harald Dobnig Critical Care 2011, 15:R104 (28 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Functional status and quality of life 12 months after discharge from a medical ICU in healthy elderly patients: a prospective observational study Emilio Sacanella, Joan Manel Pérez-Castejón, Josep Maria Nicolás, Ferran Masanés, Marga Navarro, Pedro Castro, Alfonso López-Soto Critical Care 2011, 15:R105 (28 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Extremes of weight centile are associated with increased risk of mortality in pediatric intensive care Andrew Numa, John McAweeney, Gary Williams, John Awad, Hari Ravindranathan Critical Care 2011, 15:R106 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Life expectancies and incidence rates of patients under prolonged mechanical ventilation: a population-based study during 1998 to 2007 in Taiwan Mei-Chuan Hung, Hsin-Ming Lu, Likwang Chen, Fu-Chang Hu, Soa-Yu Chan, Yuan-Horng Yan, Po-Sheng Fan, Ming-Shian Lin, Cheng-Ren Chen, Lu-Cheng Kuo, Chong-Jen Yu, Jung-Der Wang Critical Care 2011, 15:R107 (1 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time Simon J Stanworth, Timothy S Walsh, Robin J Prescott, Robert J Lee, Douglas M Watson, Duncan Wyncoll, the Intensive Care Study of Coagulopathy (ISOC) investigators Critical Care 2011, 15:R108 (5 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary There is substantial variation in clinical use of fresh frozen plasma in terms of indication and dosage, with a high proportion of transfusions being of uncertain and unproven clinical benefit.
	Research Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients Alexander Koch, Lutz Hamann, Matthias Schott, Olaf Boehm, Dirk Grotemeyer, Muhammed Kurt, Carsten Schwenke, Ralf R Schumann, Stefan R Bornstein, Kai Zacharowski Critical Care 2011, 15:R109 (5 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Activation of factor VII-activating protease in human inflammation: a sensor for cell death Femke Stephan, Jan A Hazelzet, Ingrid Bulder, Marja A Boermeester, JW van Till, Tom van der Poll, Walter A Wuillemin, Lucien A Aarden, Sacha Zeerleder Critical Care 2011, 15:R110 (5 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research An evidence-based recommendation on bed head elevation for mechanically ventilated patients Barbara S Niël-Weise, Petra Gastmeier, Axel Kola, Ralf P Vonberg, Jan C Wille, Peterhans J van den Broek, the Bed Head Elevation Study Group Critical Care 2011, 15:R111 (11 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa Catherine Kaminski, Jean-François Timsit, Yohann Dubois, Jean-Ralph Zahar, Maïté Garrouste-Orgeas, Aurélien Vesin, Elie Azoulay, Céline Feger, Anne-Sylvie Dumenil, Christophe Adrie, Yves Cohen, Bernard Allaouchiche, the OUTCOMEREA study group Critical Care 2011, 15:R112 (11 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation Sang Hwang, Ji-Eun Kim, Kyou-Sup Han, Hyun Kim Critical Care 2011, 15:R113 (14 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting Gregor Prosen, Petra Klemen, Matej Strnad, Štefek Grmec Critical Care 2011, 15:R114 (14 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Soluble triggering receptor on myeloid cells-1 is expressed in the course of non-infectious inflammation after traumatic lung contusion: a prospective cohort study Tobias M Bingold, Barbara Pullmann, Sven Sartorius, Emanuel V Geiger, Ingo Marzi, Kai Zacharowski, Heimo Wissing, Bertram Scheller Critical Care 2011, 15:R115 (15 April 2011) Abstract \| Full text \| PDF \| PubMed
	Research Age of red blood cells and mortality in the critically ill Ville Pettilä, Andrew J Westbrook, Alistair D Nichol, Michael J Bailey, Erica M Wood, Gillian Syres, Louise E Phillips, Alison Street, Craig French, Lynnette Murray, Neil Orford, John D Santamaria, Rinaldo Bellomo, David J Cooper, the Blood Observational Study Investigators for the ANZICS Clinical Trials Group Critical Care 2011, 15:R116 (15 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research High-dose tranexamic acid reduces blood loss in postpartum haemorrhage Anne-Sophie Ducloy-Bouthors, Brigitte Jude, Alain Duhamel, Françoise Broisin, Cyril Huissoud, Hawa Keita-Meyer, Laurent Mandelbrot, Nadia Tillouche, Sylvie Fontaine, Françoise Le Goueff, Sandrine Depret-Mosser, Benoit Vallet, The EXADELI Study Group, Sophie Susen Critical Care 2011, 15:R117 (15 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Research Transpulmonary thermodilution for hemodynamic measurements in severely burned children Ludwik K Branski, David N Herndon, Jaron F Byrd, Michael P Kinsky, Jong O Lee, Shawn P Fagan, Marc G Jeschke Critical Care 2011, 15:R118 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter Respiratory support withdrawal in intensive care units: international differences stressed and straightened! Jelle L Epker, Yorick J de Groot, Erwin J Kompanje Critical Care 2011, 15:405 (2 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Use of minimally invasive hemodynamic monitoring to assess dynamic changes in cardiac output at the bedside Michael R Pinsky Critical Care 2011, 15:406 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter How did you sleep in the ICU? Laetitia Franck, Jean-Pierre Tourtier, Nicolas Libert, Laurent Grasser, Yves Auroy Critical Care 2011, 15:408 (7 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Recombinant factor VIIa and factor VIII treatment for acquired factor VIII deficiency: a case of repeated thrombotic endotracheal occlusion in a mechanically ventilated patient Stefan Lauer, Martin Westphal, Lars G Fischer, Andreas Meißner, Hugo Van Aken, Hendrik Freise Critical Care 2011, 15:407 (9 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Selective digestive decontamination is superior to selective oropharyngeal decontamination Luciano Silvestri, Nia Taylor, Durk F Zandstra, Hendrick KF van Saene Critical Care 2011, 15:411 (18 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Cytomegalovirus infection monitored by quantitative real-time PCR in critically ill patients Julien Bordes, Tiphaine Gaillard, Jérôme Maslin, Pierre Esnault, Philippe Goutorbe, Patrick Brisou Critical Care 2011, 15:412 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Early corticosteroid treatment for severe pneumonia caused by 2009 H1N1 influenza virus Hong-Ryang Kil, Jae-Ho Lee, Kyung-Yil Lee, Jung-Woo Rhim, You-Sook Youn, Jin-Han Kang Critical Care 2011, 15:413 (22 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Letter Pulse pressure variation, stroke volume variation and dynamic arterial elastance Raphael Giraud, Nils Siegenthaler, Karim Bendjelid Critical Care 2011, 15:414 (23 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Does renal replacement therapy increase mortality in the ICU? David Pestaña Critical Care 2011, 15:415 (24 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Licorice consumption-associated thunderclap headache: posterior reversible encephalopathy syndrome or subarachnoid hemorrhage? Hongliang Zhang, Xiao-Feng Wang, Jiang Wu Critical Care 2011, 15:416 (31 March 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Microsphere contrast echocardiography in the critical care complex David G Platts, John F Fraser Critical Care 2011, 15:417 (6 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Distinction between induction and maintenance dosing in continuous renal replacement therapy Graeme MacLaren Critical Care 2011, 15:419 (26 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Older patients in the ICU: a cautious analysis of epidemiologic data is required Thomas Fassier, Antoine Duclos Critical Care 2011, 15:421 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter Diagnosis of invasive bronchial-pulmonary aspergillosis in patients with chronic obstructive respiratory diseases Pierre Bulpa, Alain Dive Critical Care 2011, 15:420 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
	Letter In critically ill patients the procalcitonin level can be misleading Jacqueline Koeze, MG Ron Hendrix, Frank AJTM van den Bergh, René ML Brouwer, Jan G Zijlstra Critical Care 2011, 15:422 (28 April 2011) Abstract \| Full text \| PDF \| PubMed

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