Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
1 Emergency Department, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK
2 Department of Public Health Sciences, Edinburgh University, Teviot Place, Edinburgh, EH8 9AG, UK
3 Department of Critical Care, Clinical Sciences and Community Health, Edinburgh University and Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh, EH16 4SA, UK
Critical Care 2011, 15:126 doi:10.1186/cc10014
See related research by Stanworth et al., http://ccforum.com/content/14/6/R239Published: 1 March 2011
The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, which might trigger a proactive haemostatic resuscitation strategy, are not currently available. We review recent literature relating to predictors of massive transfusions and the relationship between transfusion and mortality.