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Commentary

Statins: a role in infected critically ill patients?

Jonathon Dean Truwit

Author Affiliations

Pulmonary and Critical Care Medicine, University of Virginia, Box 800793, Charlottesville, VA 22908, USA

Critical Care 2011, 15:145  doi:10.1186/cc10086


Please see related research by Terblanche et al., http://ccforum.com/content/15/1/R74

Published: 1 April 2011

Abstract

Terblanche and colleagues add to the ongoing controversy over the role, if any, for statins in patients with sepsis. The authors note that statins fail to prevent progression to organ dysfunction in critically ill patients. However, like most publications, the study is retrospective and stimulates the controversy but fails to resolve it. The time has come for robust randomized controlled clinical trials.