Recombinant factor VIIa and factor VIII treatment for acquired factor VIII deficiency: a case of repeated thrombotic endotracheal occlusion in a mechanically ventilated patient
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* Corresponding author: Stefan Lauer stlauer@gmx.net
1 Department of Anesthesiology and Intensive Care Medicine, University Hospital Muenster, Albert-Schweitzer-Str. 33, 48149 Muenster, Germany
2 Fresenius Kabi AG, Else-Kröner-Strasse 1, 61352 Bad Homburg, Germany
Critical Care 2011, 15:407 doi:10.1186/cc10041
Published: 9 March 2011First paragraph (this article has no abstract)
Acquired hemophilia A is caused by autoantibodies to coagulation factor VIII (FVIII). Preoperative diagnosis is impaired by the lack of a personal or family history of bleeding episodes. Therefore, surgical procedures can lead to life-threatening hemorrhage [1].