Table 3

Multivariate logistic regression analysis for mortality analysis: results of stepwise selection procedures

Characteristics

Coefficient

SEM

Odds ratio

95% CI

P value

SAPS II above 65 upon ICU admission^a

2.01

0.61

7.53

2.30 to 24.7

< 0.001

Lactatemia upon ICU admission (mmol/L)

0.18

0.08

1.20

1.04 to 1.39

0.01

Plasma pH difference below 0.10 between day 1 and day 0^a

-1.74

0.59

0.18

0.05 to 0.56

0.003

SAPS II: Severity Acute Physiology Score II [22]. Variables entered into the model were those significantly different between survivors and nonsurvivors in the univariate analysis (Table 1 and Figure 2) upon ICU admission: age above 65 years, SAPS II above 65, SOFA above 10, anion gap, base excess, effective strong ion difference, albuminemia, lactatemia and administration of vasopressors. Plasma level difference between day 1 and day 0 for pH, bicarbonate and base excess and the amount of sodium bicarbonate (in mmol/kg) that were administered within the first 24 hours of ICU stay were also entered into the model. ^aDiscretized according to median value.

Jung et al. Critical Care 2011 15:R238   doi:10.1186/cc10487