Balanced study groups in a randomized trial - authors' response
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* Corresponding author: Jan Benes benesj@fnplzen.cz
Department of Anesthesiology and Intensive Care, Charles University hospital, alej Svobody 80, Plzen, 304 60, Czech Republic
Critical Care 2011, 15:460 doi:10.1186/cc10549
See related research by Benes et al., http://ccforum.com/content/14/3/R118
Published: 8 December 2011First paragraph (this article has no abstract)
Thank you for giving us the chance to reply to the comment raised by Dr Munis [1]. As we wrote in the Materials and methods section of our article [2], we used a sealed envelope, simple randomization procedure in a 1:1 proportion of intervention to control. No stratification was performed, although there are some factors affecting the study group homogeneity.