Table 2

Randomized controlled trials of shorter versus longer antibiotic therapy that included patients with bacteremia.

Author

Syndrome

All patients blood cultured?

Short-arm group, number (percentage) bacteremic

Long-arm group, number (percentage) bacteremic

Chowdhary et al. [26]

Non-Staphylococcus aureus bacteremia

Yes

26/26 (100%)

26/26 (100%)

S. aureus bacteremia

Yes

7/7 (100%)

7/7 (100%)

Runyon et al. [28]

Peritonitis

Yes

9/43 (20.9%)

17/47 (36.2%)

Chaudhry et al. [29]

Peritonitis

Yes

6/25 (24%)

8/25 (32%)

Jernelius et al. [47]

Pyelonephritis

Yes

5/32 (15.6%)

4/29 (13.8%)

Cheng et al. [48]

Pyelonephritis

Yes

1/41 (2.4%)

3/39 (7.7%)

Engle et al. [30]

Pneumonia

Yes

0/14 (0%)

0/12 (0%)

Engle et al. [31]

Pneumonia

Yes

0/35 (0%)

0/38 (0%)

Vuori-Holopainen et al. [32]

Pneumonia

Yes

N/A

N/A

Tellier et al. [36]

Pneumonia

Yes

14/187 (7.5%)

9/191 (4.7%)

File et al. [35]

Pneumonia

Yes

N/A

N/A

Dunbar et al. [37]

Pneumonia

Yes

7/256 (2.7%)

7/272 (2.6%)

Leophonte et al. [39]

Pneumonia

Yes

11/125 (8.8%)

12/119 (10.1%)

Siegel et al. [38]

Pneumonia

Yes

2/24 (8.3%)

4/22 (18.2%)

El Moussaoui et al. [40]

Pneumonia

Unclear

6/56 (10.7%)

8/63 (12.7%)

Chastre et al. [42]

Pneumonia

Yes

14/197 (7.1%)

14/204 (6.9%)

N/A, not applicable.

Havey et al. Critical Care 2011 15:R267   doi:10.1186/cc10545