Critical Care | Volume 16 Issue 1

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Articles

	Volume 16 Issue 1
	Comment
	Viewpoint A critique of fluid bolus resuscitation in severe sepsis Andrew K Hilton, Rinaldo Bellomo Critical Care 2012, 16:302 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint A handoff is not a telegram: an understanding of the patient is co-constructed Michael D Cohen, Brian Hilligoss, André Kajdacsy-Balla Amaral Critical Care 2011, 16:303 (8 February 2012) Abstract \| Full text \| PDF
	Commentary Do we need an assessment of the nutrition risk in the critically ill patient? Jean-Charles Preiser Critical Care 2012, 16:101 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Knowledge is power: studying critical incidents in intensive care Panagiotis Kiekkas, Diamanto Aretha, Nikolaos Stefanopoulos, George I Baltopoulos Critical Care 2012, 16:102 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Copeptin in aneurysmal subarachnoid hemorrhage Rafael J Tamargo Critical Care 2012, 16:103 (10 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary The key to advanced airways during cardiac arrest: well trained and early Peter T Morley Critical Care 2011, 16:104 (11 January 2012) Abstract \| Full text \| PDF
	Commentary Standardizing data collection in severe trauma: call for linking up Doortje C Engel Critical Care 2011, 16:105 (12 January 2012) Abstract \| Full text \| PDF
	Commentary Sedation, delirium and psychological distress: let's not be deluded Richard D Griffiths Critical Care 2012, 16:109 (16 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Pragmatic fluid optimization in high-risk surgery patients: when pragmatism dilutes the benefits Daniel A Reuter Critical Care 2012, 16:106 (31 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Drotrecogin alfa (activated) ... a sad final fizzle to a roller-coaster party Derek C Angus Critical Care 2012, 16:107 (6 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Lung recruitment in ARDS: We are still confused, but on a higher PEEP level Peter M Spieth, Marcelo Gama de Abreu Critical Care 2012, 16:108 (9 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hydroxyethylstarch 200/0.5 - the horse has bolted Neil Soni Critical Care 2012, 16:110 (16 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine? Florian Wagner, Pierre Asfar, Michael Georgieff, Peter Radermacher, Katja Wagner Critical Care 2012, 16:112 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary What is the optimal rate of failed extubation? James S Krinsley, Praveen K Reddy, Abid Iqbal Critical Care 2012, 16:111 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hypertonic saline, not mannitol, should be considered gold-standard medical therapy for intracranial hypertension Nicholas F Marko Critical Care 2012, 16:113 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Nurses and ventilators Amal Jubran Critical Care 2012, 16:115 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Extravascular lung water in acute respiratory distress syndrome: potential clinical value, assumptions and limitations Luigi Camporota, Mark De Neef, Richard Beale Critical Care 2012, 16:114 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Pro/Con debate: Are barrier precautions cost-effective in improving patient outcomes in the intensive care unit? Nisha Thampi, Andrew M Morris Critical Care 2011, 16:202 (19 January 2012) Abstract \| Full text \| PDF
	Review Clinical review: Use of renal replacement therapies in special groups of ICU patients Eric AJ Hoste, Annemieke Dhondt Critical Care 2011, 16:201 (19 January 2012) Abstract \| Full text \| PDF
	Review Clinical review: Sepsis and septic shock - the potential of gene arrays Hector R Wong Critical Care 2012, 16:204 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Humidifiers during non-invasive ventilation - key topics and practical implications Antonio M Esquinas Rodriguez, Raffaele Scala, Arie Soroksky, Ahmed BaHammam, Alan de Klerk, Arschang Valipour, Davide Chiumello, Claude Martin, Anne E Holland Critical Care 2011, 16:203 (8 February 2012) Abstract \| Full text \| PDF
	Report
	Journal club critique Glucocorticoid therapy for trauma - ready for prime time? Venkata S Aleti, Sachin Yende Critical Care 2011, 16:301 (20 January 2012) Abstract \| Full text \| PDF
	Journal club critique Beyond checklists: Using clinician prompts to achieve meaningful ICU quality improvement Osamudiamen Idahosa, Jeremy M Kahn Critical Care 2012, 16:305 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Journal club critique New obstacles to improving the quality of end-of-life care in ICU Maxim V Bocharov, Jeremy M Kahn Critical Care 2012, 16:304 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Correction Correction: Screening and control of methicillin-resistant Staphylococcus aureus in 186 intensive care units: different situations and individual solutions Anke Kohlenberg, Frank Schwab, Michael Behnke, Petra Gastmeier Critical Care 2012, 16:402 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock Michelle S Chew, Lilian Ihrman, Joachim During, Lill Bergenzaun, Anders Ersson, Johan Undén, Jörgen Ryden, Eva Åkerman, Marina Larsson Critical Care 2012, 16:R1 (3 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Plasma neutrophil gelatinase-associated lipocalin for the prediction of acute kidney injury in acute heart failure Tobias Breidthardt, Thenral Socrates, Beatrice Drexler, Markus Noveanu, Corinna Heinisch, Nisha Arenja, Theresia Klima, Christina Züsli, Tobias Reichlin, Mihael Potocki, Raphael Twerenbold, Jürg Steiger, Christian Mueller Critical Care 2012, 16:R2 (7 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early initiation of low-dose corticosteroid therapy in the management of septic shock: a retrospective observational study Hye Park, Gee Suh, Jae-Uk Song, Hongseok Yoo, Ik Jo, Tae Shin, So Lim, Sookyoung Woo, Kyeongman Jeon Critical Care 2012, 16:R3 (7 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research How large is the lung recruitability in early acute respiratory distress syndrome: a prospective case series of patients monitored by computed tomography Gustavo FJ de Matos, Fabiana Stanzani, Rogerio H Passos, Mauricio F Fontana, Renata Albaladejo, Raquel E Caserta, Durval CB Santos, João Borges, Marcelo BP Amato, Carmen SV Barbas Critical Care 2012, 16:R4 (8 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Three-year mortality among alcoholic patients after intensive care: a population-based cohort study Steffen Christensen, Martin B Johansen, Lars Pedersen, Reinhold Jensen, Kim M Larsen, Anders Larsson, Else Tønnesen, Christian F Christiansen, Henrik T Sørensen Critical Care 2012, 16:R5 (8 January 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Carboxyhemoglobin levels in medical intensive care patients: a retrospective, observational study Andreas S Fazekas, Marlene Wewalka, Christian Zauner, Georg-Christian Funk Critical Care 2012, 16:R6 (11 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Clinical utility of biomarkers of endothelial activation in sepsis-a systematic review Katharine Xing, Srinivas Murthy, W Conrad Liles, Jeffrey M Singh Critical Care 2012, 16:R7 (16 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Influence of respiratory rate and end-expiratory pressure variation on cyclic alveolar recruitment in an experimental lung injury model Erik K Hartmann, Stefan Boehme, Alexander Bentley, Bastian Duenges, Klaus U Klein, Amelie Elsaesser, James E Baumgardner, Matthias David, Klaus Markstaller Critical Care 2012, 16:R8 (16 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose Runkuan Yang, Xiaoping Zou, Marja-Leena Koskinen, Jyrki Tenhunen Critical Care 2012, 16:R9 (16 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup Leonardo Lorente, Ruth Iceta, María M Martín, Esther López-Gallardo, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Julio Montoya, Eduardo Ruiz-Pesini Critical Care 2012, 16:R10 (17 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Relationship between thyroid function and ICU mortality: a prospective observation study Feilong Wang, Wenzhi Pan, Hairong Wang, Shuyun Wang, Shuming Pan, Junbo Ge Critical Care 2012, 16:R11 (19 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern Daithi S Heffernan, Sean F Monaghan, Rajan K Thakkar, Jason T Machan, William G Cioffi, Alfred Ayala Critical Care 2012, 16:R12 (20 January 2012) Abstract \| Provisional PDF \| PubMed
	Research Population-based incidence, mortality and quality of life in critically ill patients treated with renal replacement therapy: a nationwide retrospective cohort study in finnish intensive care units Suvi T Vaara, Ville Pettilä, Matti Reinikainen, Kirsi-Maija Kaukonen, the Finnish Intensive Care Consortium Critical Care 2012, 16:R13 (20 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial Peter Pickkers, Suzanne Heemskerk, Jeroen Schouten, Pierre-François Laterre, Jean-Louis Vincent, Albertus Beishuizen, Philippe G Jorens, Herbert Spapen, Michael Bulitta, Wilbert HM Peters, Johannes G van der Hoeven Critical Care 2012, 16:R14 (23 January 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Nutritional support and brain tissue glucose metabolism in poor-grade SAH: a retrospective observational study J Michael Schmidt, Jan Claassen, Sang-Bae Ko, Hector Lantigua, Mary Presciutti, Kiwon Lee, E Sander Connolly, Stephan A Mayer, David S Seres, Neeraj Badjatia Critical Care 2012, 16:R15 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Research Impairment of renal function using hyperoncotic colloids in a two hit model of shock: a prospective randomized study Tim Simon, Tobias Schuerholz, Lars Hüter, Michael Sasse, Florian Heyder, Wolfgang Pfister, Gernot Marx Critical Care 2012, 16:R16 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively: a case control study Martina Nowak-Machen, James D Rawn, Prem S Shekar, Aya Mitani, Sagun Tuli, Tobias M Bingold, Garrett Lawlor, Holger K Eltzschig, Stanton K Shernan, Peter Rosenberger Critical Care 2012, 16:R17 (25 January 2012) Abstract \| Provisional PDF \| PubMed
	Research Low doses of esmolol and phenylephrine act as diuretics during intravenous anesthesia Yu Li, Hai Zhu, Xiaozhu Zheng, Han Chen, Liang Shao, Robert G Hahn Critical Care 2012, 16:R18 (30 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI) John-Paul Tung, John F Fraser, Maria Nataatmadja, Kathryn I Colebourne, Adrian G Barnett, Kristen M Glenister, Anna Y Zhou, Peter Wood, Christopher C Silliman, Yoke L Fung Critical Care 2012, 16:R19 (1 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research A prospective randomized open-label crossover trial of regional citrate anticoagulation vs. anticoagulation free liver dialysis by the Molecular Adsorbents Recirculating System Björn Meijers, Wim Laleman, Pieter Vermeersch, Frederik Nevens, Alexander Wilmer, Pieter Evenepoel Critical Care 2012, 16:R20 (3 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Clinical experience with power-injectable PICCs in intensive care patients Mauro Pittiruti, Alberto Brutti, Davide Celentano, Massimiliano Pomponi, Daniele G Biasucci, Maria Annetta, Giancarlo Scoppettuolo Critical Care 2012, 16:R21 (4 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Power injectable peripherally inserted central catheters can be used successfully in most intensive care unit patients with few contraindications and low rates of complications, similar to central venous catheters (CVC).
	Research Costs and benefits of rapid screening of methicillin-resistant Staphylococcus aureus carriage in intensive care units: a prospective multicenter study Marjan Wassenberg, Jan Kluytmans, Stephanie Erdkamp, Ron Bosboom, Anton Buiting, Erika van Elzakker, Willem Melchers, Steven Thijsen, Annet Troelstra, Christina Vandenbroucke-Grauls, Caroline Visser, Andreas Voss, Petra Wolffs, Mireille Wulf, Ton van Zwet, Ardine de Wit, Marc Bonten Critical Care 2012, 16:R22 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hepatorenal syndrome: the 8^thinternational consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group Mitra K Nadim, John A Kellum, Andrew Davenport, Florence Wong, Connie Davis, Neesh Pannu, Ashita Tolwani, Rinaldo Bellomo, Yuri S Genyk, The ADQI Workgroup Critical Care 2012, 16:R23 (9 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Patient safety in pre-hospital emergency tracheal intubation: a comprehensive meta-analysis of the intubation success rates of EMS providers Hans Lossius, Jo Røislien, David J Lockey Critical Care 2012, 16:R24 (11 February 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Alterations in arterial function after high-voltage electrical injury Kyoung-Ha Park, Woo Park, Min-Kyu Kim, Hyun-Sook Kim, Seong Kim, Goo-Yeong Cho, Young-Jin Choi Critical Care 2012, 16:R25 (12 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inter-hospital transport of critically ill patients; expect surprises Joep M Droogh, Marije Smit, Jakob Hut, Ronald de Vos, Jack J M Ligtenberg, Jan G Zijlstra Critical Care 2012, 16:R26 (12 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Technical failure of medical utensils during inter-hospital transport can largely impact on patient health, highlighting the importance of specialist training and knowledge in the use of emergency equipment within transport teams.
	Research Patient-care time allocation by nurse practitioners and physician assistants in the intensive care unit David L Carpenter, Sara R Gregg, Daniel S Owens, Timothy G Buchman, Craig M Coopersmith Critical Care 2012, 16:R27 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial Jong Kim, Joowon Chung, Sang-Ho Choi, Hang Jang, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh Critical Care 2012, 16:R28 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Assessment of left ventricular ejection fraction using an ultrasonic stethoscope in critically ill patients Jean-Bernard Amiel, Ana Grümann, Gwenaëlle Lhéritier, Marc Clavel, Bruno François, Nicolas Pichon, Anthony Dugard, Benoît Marin, Philippe Vignon Critical Care 2012, 16:R29 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early recognition of the 2009 pandemic influenza A (H1N1) pneumonia by chest ultrasound Americo Testa, Gino Soldati, Roberto Copetti, Rosangela Giannuzzi, Grazia Portale, Nicolò Gentiloni-Silveri Critical Care 2012, 16:R30 (17 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Bedside chest ultrasonography can accurately provide early stage detection of patients with pandemic influenza A (H1N1) pneumonia even when chest radiography is normal.
	Research A placebo-controlled, double-blind, dose-escalation study to assess the safety, tolerability and pharmacokinetics/pharmacodynamics of single and multiple intravenous infusions of AZD9773 in patients with severe sepsis and septic shock Peter E Morris, Brian Zeno, Andrew C Bernard, Xiangning Huang, Shampa Das, Timi Edeki, Steven G Simonson, Gordon R Bernard Critical Care 2012, 16:R31 (17 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis Alessandra Bitto, Letteria Minutoli, Antonio David, Natasha Irrera, Mariagrazia Rinaldi, Francesco S Venuti, Francesco Squadrito, Domenica Altavilla Critical Care 2012, 16:R32 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group, Byung Lee, Daisuke Inui, Gee Suh, Jae Kim, Jae Kwon, Jisook Park, Keiichi Tada, Keiji Tanaka, Kenichi Ietsugu, Kenji Uehara, Kentaro Dote, Kimitaka Tajimi, Kiyoshi Morita, Koichi Matsuo, Koji Hoshino, Koji Hosokawa, Kook Lee, Kyoung Lee, Makoto Takatori, Masaji Nishimura, Masamitsu Sanui, Masanori Ito, Moritoki Egi, Naofumi Honda, Naoko Okayama, Nobuaki Shime, Ryosuke Tsuruta, Satoshi Nogami, Seok-Hwa Yoon et al. Critical Care 2012, 16:R33 (28 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock Laurent Muller, Samir Jaber, Nicolas Molinari, Laurent Favier, Jérôme Larché, Gilles Motte, Sonia Lazarovici, Luc Jacques, Sandrine Alonso, Marc Leone, Jean Constantin, Bernard Allaouchiche, Carey Suehs, Jean-Yves Lefrant, the AzuRéa Group Critical Care 2012, 16:R34 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Duration of antibiotic therapy in bacteraemia Matt P Wise, Matt PG Morgan, Anton G Saayman Critical Care 2012, 16:403 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter The importance of diagnostic testing in the management of community-acquired respiratory infection during influenza season Tom WL Holmes, Andrew Campbell, Jaisi Sinha, Matt P Wise Critical Care 2011, 16:401 (9 January 2012) Abstract \| Full text \| PDF
	Letter LightCycler SeptiFast technology in patients with solid malignancies: clinical utility for rapid etiologic diagnosis of sepsis Lenka Dubská, Martina Vyskočilová, Dagmar Minaříková, Petr Jelínek, Renata Tejkalová, Dalibor Valík Critical Care 2011, 16:404 (17 January 2012) Abstract \| Full text \| PDF
	Letter High-frequency oscillatory ventilation after cardiac surgery: a treatment for all ages Ravi S Tripathi, Erica J Stein, Juan A Crestanello, Thomas J Papadimos Critical Care 2012, 16:405 (23 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Passive immunotherapy of sepsis with intravenous immune globulin: not all IVIg preparations are created equal Tchavdar Vassilev, Michael Bauer Critical Care 2012, 16:407 (25 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Use of carperitide infusion for acutely decompensated heart failure Yoshihisa Morita, Shun Kohsaka, Kazuki Oshima, Tsutomu Yoshikawa, Keiichi Fukuda Critical Care 2012, 16:406 (25 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Effect of acute hyperventilation on the venous-arterial PCO₂difference Jihad Mallat Critical Care 2012, 16:408 (30 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Optimization of oxygen delivery during high-risk surgery: keeping the concept but refining goals for inotrope infusion? Emmanuel Futier, Benoit Vallet Critical Care 2012, 16:409 (6 February 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Inflammasome and caspase-1 inhibition caused by Bcl-2 and Bcl-X_Lmay influence cytokine responses of lipopolysaccharide-stimulated peripheral blood mononuclear cells from septic patients Zhao-Jun Liu, Jia-Lin Liu, Hong-Ping Qu Critical Care 2012, 16:410 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Carboxyhemoglobin levels in medical intensive care patients Matthew E Cove, Michael R Pinsky Critical Care 2012, 16:411 (16 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	Volume 16 Issue 1
	Comment
	Viewpoint A critique of fluid bolus resuscitation in severe sepsis Andrew K Hilton, Rinaldo Bellomo Critical Care 2012, 16:302 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint A handoff is not a telegram: an understanding of the patient is co-constructed Michael D Cohen, Brian Hilligoss, André Kajdacsy-Balla Amaral Critical Care 2011, 16:303 (8 February 2012) Abstract \| Full text \| PDF
	Commentary Do we need an assessment of the nutrition risk in the critically ill patient? Jean-Charles Preiser Critical Care 2012, 16:101 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Knowledge is power: studying critical incidents in intensive care Panagiotis Kiekkas, Diamanto Aretha, Nikolaos Stefanopoulos, George I Baltopoulos Critical Care 2012, 16:102 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Copeptin in aneurysmal subarachnoid hemorrhage Rafael J Tamargo Critical Care 2012, 16:103 (10 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary The key to advanced airways during cardiac arrest: well trained and early Peter T Morley Critical Care 2011, 16:104 (11 January 2012) Abstract \| Full text \| PDF
	Commentary Standardizing data collection in severe trauma: call for linking up Doortje C Engel Critical Care 2011, 16:105 (12 January 2012) Abstract \| Full text \| PDF
	Commentary Sedation, delirium and psychological distress: let's not be deluded Richard D Griffiths Critical Care 2012, 16:109 (16 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Pragmatic fluid optimization in high-risk surgery patients: when pragmatism dilutes the benefits Daniel A Reuter Critical Care 2012, 16:106 (31 January 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Drotrecogin alfa (activated) ... a sad final fizzle to a roller-coaster party Derek C Angus Critical Care 2012, 16:107 (6 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Lung recruitment in ARDS: We are still confused, but on a higher PEEP level Peter M Spieth, Marcelo Gama de Abreu Critical Care 2012, 16:108 (9 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hydroxyethylstarch 200/0.5 - the horse has bolted Neil Soni Critical Care 2012, 16:110 (16 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine? Florian Wagner, Pierre Asfar, Michael Georgieff, Peter Radermacher, Katja Wagner Critical Care 2012, 16:112 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary What is the optimal rate of failed extubation? James S Krinsley, Praveen K Reddy, Abid Iqbal Critical Care 2012, 16:111 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hypertonic saline, not mannitol, should be considered gold-standard medical therapy for intracranial hypertension Nicholas F Marko Critical Care 2012, 16:113 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Nurses and ventilators Amal Jubran Critical Care 2012, 16:115 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Extravascular lung water in acute respiratory distress syndrome: potential clinical value, assumptions and limitations Luigi Camporota, Mark De Neef, Richard Beale Critical Care 2012, 16:114 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Pro/Con debate: Are barrier precautions cost-effective in improving patient outcomes in the intensive care unit? Nisha Thampi, Andrew M Morris Critical Care 2011, 16:202 (19 January 2012) Abstract \| Full text \| PDF
	Review Clinical review: Use of renal replacement therapies in special groups of ICU patients Eric AJ Hoste, Annemieke Dhondt Critical Care 2011, 16:201 (19 January 2012) Abstract \| Full text \| PDF
	Review Clinical review: Sepsis and septic shock - the potential of gene arrays Hector R Wong Critical Care 2012, 16:204 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Humidifiers during non-invasive ventilation - key topics and practical implications Antonio M Esquinas Rodriguez, Raffaele Scala, Arie Soroksky, Ahmed BaHammam, Alan de Klerk, Arschang Valipour, Davide Chiumello, Claude Martin, Anne E Holland Critical Care 2011, 16:203 (8 February 2012) Abstract \| Full text \| PDF
	Report
	Journal club critique Glucocorticoid therapy for trauma - ready for prime time? Venkata S Aleti, Sachin Yende Critical Care 2011, 16:301 (20 January 2012) Abstract \| Full text \| PDF
	Journal club critique Beyond checklists: Using clinician prompts to achieve meaningful ICU quality improvement Osamudiamen Idahosa, Jeremy M Kahn Critical Care 2012, 16:305 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Journal club critique New obstacles to improving the quality of end-of-life care in ICU Maxim V Bocharov, Jeremy M Kahn Critical Care 2012, 16:304 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Correction Correction: Screening and control of methicillin-resistant Staphylococcus aureus in 186 intensive care units: different situations and individual solutions Anke Kohlenberg, Frank Schwab, Michael Behnke, Petra Gastmeier Critical Care 2012, 16:402 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research
	Research Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock Michelle S Chew, Lilian Ihrman, Joachim During, Lill Bergenzaun, Anders Ersson, Johan Undén, Jörgen Ryden, Eva Åkerman, Marina Larsson Critical Care 2012, 16:R1 (3 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Plasma neutrophil gelatinase-associated lipocalin for the prediction of acute kidney injury in acute heart failure Tobias Breidthardt, Thenral Socrates, Beatrice Drexler, Markus Noveanu, Corinna Heinisch, Nisha Arenja, Theresia Klima, Christina Züsli, Tobias Reichlin, Mihael Potocki, Raphael Twerenbold, Jürg Steiger, Christian Mueller Critical Care 2012, 16:R2 (7 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early initiation of low-dose corticosteroid therapy in the management of septic shock: a retrospective observational study Hye Park, Gee Suh, Jae-Uk Song, Hongseok Yoo, Ik Jo, Tae Shin, So Lim, Sookyoung Woo, Kyeongman Jeon Critical Care 2012, 16:R3 (7 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research How large is the lung recruitability in early acute respiratory distress syndrome: a prospective case series of patients monitored by computed tomography Gustavo FJ de Matos, Fabiana Stanzani, Rogerio H Passos, Mauricio F Fontana, Renata Albaladejo, Raquel E Caserta, Durval CB Santos, João Borges, Marcelo BP Amato, Carmen SV Barbas Critical Care 2012, 16:R4 (8 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Three-year mortality among alcoholic patients after intensive care: a population-based cohort study Steffen Christensen, Martin B Johansen, Lars Pedersen, Reinhold Jensen, Kim M Larsen, Anders Larsson, Else Tønnesen, Christian F Christiansen, Henrik T Sørensen Critical Care 2012, 16:R5 (8 January 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Carboxyhemoglobin levels in medical intensive care patients: a retrospective, observational study Andreas S Fazekas, Marlene Wewalka, Christian Zauner, Georg-Christian Funk Critical Care 2012, 16:R6 (11 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Clinical utility of biomarkers of endothelial activation in sepsis-a systematic review Katharine Xing, Srinivas Murthy, W Conrad Liles, Jeffrey M Singh Critical Care 2012, 16:R7 (16 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Influence of respiratory rate and end-expiratory pressure variation on cyclic alveolar recruitment in an experimental lung injury model Erik K Hartmann, Stefan Boehme, Alexander Bentley, Bastian Duenges, Klaus U Klein, Amelie Elsaesser, James E Baumgardner, Matthias David, Klaus Markstaller Critical Care 2012, 16:R8 (16 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose Runkuan Yang, Xiaoping Zou, Marja-Leena Koskinen, Jyrki Tenhunen Critical Care 2012, 16:R9 (16 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup Leonardo Lorente, Ruth Iceta, María M Martín, Esther López-Gallardo, Jordi Solé-Violán, José Blanquer, Lorenzo Labarta, César Díaz, Alejandro Jiménez, Julio Montoya, Eduardo Ruiz-Pesini Critical Care 2012, 16:R10 (17 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Relationship between thyroid function and ICU mortality: a prospective observation study Feilong Wang, Wenzhi Pan, Hairong Wang, Shuyun Wang, Shuming Pan, Junbo Ge Critical Care 2012, 16:R11 (19 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern Daithi S Heffernan, Sean F Monaghan, Rajan K Thakkar, Jason T Machan, William G Cioffi, Alfred Ayala Critical Care 2012, 16:R12 (20 January 2012) Abstract \| Provisional PDF \| PubMed
	Research Population-based incidence, mortality and quality of life in critically ill patients treated with renal replacement therapy: a nationwide retrospective cohort study in finnish intensive care units Suvi T Vaara, Ville Pettilä, Matti Reinikainen, Kirsi-Maija Kaukonen, the Finnish Intensive Care Consortium Critical Care 2012, 16:R13 (20 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial Peter Pickkers, Suzanne Heemskerk, Jeroen Schouten, Pierre-François Laterre, Jean-Louis Vincent, Albertus Beishuizen, Philippe G Jorens, Herbert Spapen, Michael Bulitta, Wilbert HM Peters, Johannes G van der Hoeven Critical Care 2012, 16:R14 (23 January 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Nutritional support and brain tissue glucose metabolism in poor-grade SAH: a retrospective observational study J Michael Schmidt, Jan Claassen, Sang-Bae Ko, Hector Lantigua, Mary Presciutti, Kiwon Lee, E Sander Connolly, Stephan A Mayer, David S Seres, Neeraj Badjatia Critical Care 2012, 16:R15 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	Research Impairment of renal function using hyperoncotic colloids in a two hit model of shock: a prospective randomized study Tim Simon, Tobias Schuerholz, Lars Hüter, Michael Sasse, Florian Heyder, Wolfgang Pfister, Gernot Marx Critical Care 2012, 16:R16 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	Research Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively: a case control study Martina Nowak-Machen, James D Rawn, Prem S Shekar, Aya Mitani, Sagun Tuli, Tobias M Bingold, Garrett Lawlor, Holger K Eltzschig, Stanton K Shernan, Peter Rosenberger Critical Care 2012, 16:R17 (25 January 2012) Abstract \| Provisional PDF \| PubMed
	Research Low doses of esmolol and phenylephrine act as diuretics during intravenous anesthesia Yu Li, Hai Zhu, Xiaozhu Zheng, Han Chen, Liang Shao, Robert G Hahn Critical Care 2012, 16:R18 (30 January 2012) Abstract \| Full text \| PDF \| PubMed
	Research Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI) John-Paul Tung, John F Fraser, Maria Nataatmadja, Kathryn I Colebourne, Adrian G Barnett, Kristen M Glenister, Anna Y Zhou, Peter Wood, Christopher C Silliman, Yoke L Fung Critical Care 2012, 16:R19 (1 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research A prospective randomized open-label crossover trial of regional citrate anticoagulation vs. anticoagulation free liver dialysis by the Molecular Adsorbents Recirculating System Björn Meijers, Wim Laleman, Pieter Vermeersch, Frederik Nevens, Alexander Wilmer, Pieter Evenepoel Critical Care 2012, 16:R20 (3 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Clinical experience with power-injectable PICCs in intensive care patients Mauro Pittiruti, Alberto Brutti, Davide Celentano, Massimiliano Pomponi, Daniele G Biasucci, Maria Annetta, Giancarlo Scoppettuolo Critical Care 2012, 16:R21 (4 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Power injectable peripherally inserted central catheters can be used successfully in most intensive care unit patients with few contraindications and low rates of complications, similar to central venous catheters (CVC).
	Research Costs and benefits of rapid screening of methicillin-resistant Staphylococcus aureus carriage in intensive care units: a prospective multicenter study Marjan Wassenberg, Jan Kluytmans, Stephanie Erdkamp, Ron Bosboom, Anton Buiting, Erika van Elzakker, Willem Melchers, Steven Thijsen, Annet Troelstra, Christina Vandenbroucke-Grauls, Caroline Visser, Andreas Voss, Petra Wolffs, Mireille Wulf, Ton van Zwet, Ardine de Wit, Marc Bonten Critical Care 2012, 16:R22 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hepatorenal syndrome: the 8^thinternational consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group Mitra K Nadim, John A Kellum, Andrew Davenport, Florence Wong, Connie Davis, Neesh Pannu, Ashita Tolwani, Rinaldo Bellomo, Yuri S Genyk, The ADQI Workgroup Critical Care 2012, 16:R23 (9 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Patient safety in pre-hospital emergency tracheal intubation: a comprehensive meta-analysis of the intubation success rates of EMS providers Hans Lossius, Jo Røislien, David J Lockey Critical Care 2012, 16:R24 (11 February 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Medicine \| F1000 Biology
	Research Alterations in arterial function after high-voltage electrical injury Kyoung-Ha Park, Woo Park, Min-Kyu Kim, Hyun-Sook Kim, Seong Kim, Goo-Yeong Cho, Young-Jin Choi Critical Care 2012, 16:R25 (12 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Inter-hospital transport of critically ill patients; expect surprises Joep M Droogh, Marije Smit, Jakob Hut, Ronald de Vos, Jack J M Ligtenberg, Jan G Zijlstra Critical Care 2012, 16:R26 (12 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Technical failure of medical utensils during inter-hospital transport can largely impact on patient health, highlighting the importance of specialist training and knowledge in the use of emergency equipment within transport teams.
	Research Patient-care time allocation by nurse practitioners and physician assistants in the intensive care unit David L Carpenter, Sara R Gregg, Daniel S Owens, Timothy G Buchman, Craig M Coopersmith Critical Care 2012, 16:R27 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial Jong Kim, Joowon Chung, Sang-Ho Choi, Hang Jang, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh Critical Care 2012, 16:R28 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Assessment of left ventricular ejection fraction using an ultrasonic stethoscope in critically ill patients Jean-Bernard Amiel, Ana Grümann, Gwenaëlle Lhéritier, Marc Clavel, Bruno François, Nicolas Pichon, Anthony Dugard, Benoît Marin, Philippe Vignon Critical Care 2012, 16:R29 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Early recognition of the 2009 pandemic influenza A (H1N1) pneumonia by chest ultrasound Americo Testa, Gino Soldati, Roberto Copetti, Rosangela Giannuzzi, Grazia Portale, Nicolò Gentiloni-Silveri Critical Care 2012, 16:R30 (17 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Bedside chest ultrasonography can accurately provide early stage detection of patients with pandemic influenza A (H1N1) pneumonia even when chest radiography is normal.
	Research A placebo-controlled, double-blind, dose-escalation study to assess the safety, tolerability and pharmacokinetics/pharmacodynamics of single and multiple intravenous infusions of AZD9773 in patients with severe sepsis and septic shock Peter E Morris, Brian Zeno, Andrew C Bernard, Xiangning Huang, Shampa Das, Timi Edeki, Steven G Simonson, Gordon R Bernard Critical Care 2012, 16:R31 (17 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis Alessandra Bitto, Letteria Minutoli, Antonio David, Natasha Irrera, Mariagrazia Rinaldi, Francesco S Venuti, Francesco Squadrito, Domenica Altavilla Critical Care 2012, 16:R32 (22 February 2012) Abstract \| Full text \| PDF \| PubMed
	Research Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group, Byung Lee, Daisuke Inui, Gee Suh, Jae Kim, Jae Kwon, Jisook Park, Keiichi Tada, Keiji Tanaka, Kenichi Ietsugu, Kenji Uehara, Kentaro Dote, Kimitaka Tajimi, Kiyoshi Morita, Koichi Matsuo, Koji Hoshino, Koji Hosokawa, Kook Lee, Kyoung Lee, Makoto Takatori, Masaji Nishimura, Masamitsu Sanui, Masanori Ito, Moritoki Egi, Naofumi Honda, Naoko Okayama, Nobuaki Shime, Ryosuke Tsuruta, Satoshi Nogami, Seok-Hwa Yoon et al. Critical Care 2012, 16:R33 (28 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock Laurent Muller, Samir Jaber, Nicolas Molinari, Laurent Favier, Jérôme Larché, Gilles Motte, Sonia Lazarovici, Luc Jacques, Sandrine Alonso, Marc Leone, Jean Constantin, Bernard Allaouchiche, Carey Suehs, Jean-Yves Lefrant, the AzuRéa Group Critical Care 2012, 16:R34 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Duration of antibiotic therapy in bacteraemia Matt P Wise, Matt PG Morgan, Anton G Saayman Critical Care 2012, 16:403 (9 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter The importance of diagnostic testing in the management of community-acquired respiratory infection during influenza season Tom WL Holmes, Andrew Campbell, Jaisi Sinha, Matt P Wise Critical Care 2011, 16:401 (9 January 2012) Abstract \| Full text \| PDF
	Letter LightCycler SeptiFast technology in patients with solid malignancies: clinical utility for rapid etiologic diagnosis of sepsis Lenka Dubská, Martina Vyskočilová, Dagmar Minaříková, Petr Jelínek, Renata Tejkalová, Dalibor Valík Critical Care 2011, 16:404 (17 January 2012) Abstract \| Full text \| PDF
	Letter High-frequency oscillatory ventilation after cardiac surgery: a treatment for all ages Ravi S Tripathi, Erica J Stein, Juan A Crestanello, Thomas J Papadimos Critical Care 2012, 16:405 (23 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Passive immunotherapy of sepsis with intravenous immune globulin: not all IVIg preparations are created equal Tchavdar Vassilev, Michael Bauer Critical Care 2012, 16:407 (25 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Use of carperitide infusion for acutely decompensated heart failure Yoshihisa Morita, Shun Kohsaka, Kazuki Oshima, Tsutomu Yoshikawa, Keiichi Fukuda Critical Care 2012, 16:406 (25 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Effect of acute hyperventilation on the venous-arterial PCO₂difference Jihad Mallat Critical Care 2012, 16:408 (30 January 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Optimization of oxygen delivery during high-risk surgery: keeping the concept but refining goals for inotrope infusion? Emmanuel Futier, Benoit Vallet Critical Care 2012, 16:409 (6 February 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Inflammasome and caspase-1 inhibition caused by Bcl-2 and Bcl-X_Lmay influence cytokine responses of lipopolysaccharide-stimulated peripheral blood mononuclear cells from septic patients Zhao-Jun Liu, Jia-Lin Liu, Hong-Ping Qu Critical Care 2012, 16:410 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Carboxyhemoglobin levels in medical intensive care patients Matthew E Cove, Michael R Pinsky Critical Care 2012, 16:411 (16 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

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