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Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial

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Jong W Kim^†, Joowon Chung^†, Sang-Ho Choi, Hang J Jang, Sang-Bum Hong, Chae-Man Lim and Younsuck Koh^*

Critical Care 2012, 16:R28 doi:10.1186/cc11197

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