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Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial

Jong Wook Kim, Joowon Chung, Sang-Ho Choi, Hang Jea Jang, Sang-Bum Hong, Chae-Man Lim and Younsuck Koh*

Critical Care 2012, 16:R28  doi:10.1186/cc11197

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