Table 4 |
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|
Multivariate logistic analysis for 28-day mortality |
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|
Patients with sepsis (N = 606) |
Patients without sepsis (N = 819) |
|||
|
|
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|
Adjusted odds ratio (95% CI) |
P-value |
Adjusted odds ratio (95% CI) |
P-value |
|
|
|
||||
|
Age (y.o., IQR) |
1.01 (0.99, 1.02) |
0.32 |
1.01 (0.98, 1.04) |
0.39 |
|
APACHE (IQR) |
1.09 (1.05, 1.12) |
< 0.001 |
1.19 (1.12, 1.27) |
< 0.001 |
|
Postoperative admission n (%) |
0.81 (0.36, 1.85) |
0.62 |
0.56 (0.24, 1.29) |
0.17 |
|
Mechanical ventilation requirement n (%) |
1.72 (1.01, 2.94) |
0.045 |
3.85 (1.40, 10.6) |
0.01 |
|
Cardiac or vascular diseases |
0.87 (0.43, 1.76) |
0.70 |
1.03 (0.38, 2.75) |
0.96 |
|
Thoracic or respiratory diseases |
1.71 (0.99, 2.94) |
0.053 |
1.87 (0.70, 4.97) |
0.21 |
|
|
||||
|
Max. body temp. during ICU stay |
||||
|
37.5°C to 38.4°C (vs. 36.5°C to 37.4°C) |
0.45 (0.24, 0.85) |
0.014 |
1.61 (0.56, 4.68) |
0.38 |
|
38.5°C to 39.4°C (vs. 36.5°C to 37.4°C) |
0.52 (0.24, 1.1) |
0.09 |
3.34 (0.88, 12.69) |
0.08 |
|
≥ 39.5°C (vs. 36.5°C -37.4°C) |
0.47 (0.19, 1.18) |
0.11 |
8.14 (1.67, 39.59) |
0.01 |
|
|
||||
|
NSAIDs |
2.61 (1.11, 6.11) |
0.028 |
0.22 (0.03, 1.74) |
0.15 |
|
Acetaminophen |
2.05 (1.19, 3.55) |
0.01 |
0.58 (0.06, 5.26) |
0.63 |
|
Cooling |
1.2 (0.70, 2.05) |
0.50 |
0.71 (0.30, 1.69) |
0.44 |
|
|
||||
|
APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidential interval; MAXICU, maximum body temperature during an ICU stay; NSAIDs, non-steroidal anti-inflammatory drugs Subgroup with MAXICU < 36.5°C was excluded from this analysis because only three patients with sepsis and none without fell within this temperature range. |
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|
Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group et al. Critical Care 2012 16:R33 doi:10.1186/cc11211 |
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