Table 4

Multivariate logistic analysis for 28-day mortality

Patients with sepsis

(N = 606)

Patients without sepsis

(N = 819)


Adjusted odds ratio

(95% CI)

P-value

Adjusted odds ratio

(95% CI)

P-value


Age (y.o., IQR)

1.01 (0.99, 1.02)

0.32

1.01 (0.98, 1.04)

0.39

APACHE (IQR)

1.09 (1.05, 1.12)

< 0.001

1.19 (1.12, 1.27)

< 0.001

Postoperative admission n (%)

0.81 (0.36, 1.85)

0.62

0.56 (0.24, 1.29)

0.17

Mechanical ventilation requirement n (%)

1.72 (1.01, 2.94)

0.045

3.85 (1.40, 10.6)

0.01

Cardiac or vascular diseases

0.87 (0.43, 1.76)

0.70

1.03 (0.38, 2.75)

0.96

Thoracic or respiratory diseases

1.71 (0.99, 2.94)

0.053

1.87 (0.70, 4.97)

0.21


Max. body temp. during ICU stay

37.5°C to 38.4°C (vs. 36.5°C to 37.4°C)

0.45 (0.24, 0.85)

0.014

1.61 (0.56, 4.68)

0.38

38.5°C to 39.4°C (vs. 36.5°C to 37.4°C)

0.52 (0.24, 1.1)

0.09

3.34 (0.88, 12.69)

0.08

≥ 39.5°C (vs. 36.5°C -37.4°C)

0.47 (0.19, 1.18)

0.11

8.14 (1.67, 39.59)

0.01


NSAIDs

2.61 (1.11, 6.11)

0.028

0.22 (0.03, 1.74)

0.15

Acetaminophen

2.05 (1.19, 3.55)

0.01

0.58 (0.06, 5.26)

0.63

Cooling

1.2 (0.70, 2.05)

0.50

0.71 (0.30, 1.69)

0.44


APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidential interval; MAXICU, maximum body temperature during an ICU stay; NSAIDs, non-steroidal anti-inflammatory drugs

Subgroup with MAXICU < 36.5°C was excluded from this analysis because only three patients with sepsis and none without fell within this temperature range.

Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group et al. Critical Care 2012 16:R33   doi:10.1186/cc11211

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