Table 5

Multivariate logistic analysis for 28-day mortality in patients with lowest body temperature > 35°C

Patients with sepsis

(N = 507)

Patients without sepsis

(N = 715)


Adjusted odds ratio

(95% CI)

P-value

Adjusted odds ratio

(95% CI)

P-value


Age (y.o., IQR)

1.02 (1.00, 1.03)

0.08

1.01 (0.98, 1.05)

0.52

APACHE (IQR)

1.07 (1.03, 1.11)

< 0.001

1.20 (1.11, 1.30)

< 0.001

Postoperative admission n (%)

0.79 (0.32, 1.91)

0.59

0.57 (0.21, 1.52)

0.26

Mechanical ventilation requirement n (%)

1.76 (0.98, 3.14)

0.06

3.49 (1.14, 10.7)

0.03

Cardiac or vascular diseases

0.85 (0.39, 1.82)

0.67

0.73 (0.24, 2.21)

0.57

Thoracic or respiratory diseases

1.23 (0.66, 2.28)

0.51

1.24 (0.40, 3.78)

0.71


MAXICU

37.5°C to 38.4°C (vs. 36.5°C to 37.4°C)

0.42 (0.20, 0.88)

0.02

3.18 (0.78, 12.9)

0.11

38.5°C to 39.4°C (vs. 36.5°C to 37.4°C)

0.60 (0.25, 1.43)

0.25

7.49 (1.47, 38.1)

0.02

≥ 39.5°C (vs. 36.5°C to 37.4°C)

0.59 (0.21, 1.68)

0.32

11.7 (1.58, 87.0)

0.02


NSAIDs

2.48 (1.02, 6.01)

0.04

0.26 (0.032, 2.19)

0.22

Acetaminophen

1.95 (1.06, 3.57)

0.03

0.61 (0.23, 1.61)

0.32

Cooling

1.23 (0.69, 2.21)

0.47

1.26 (0.14, 11.0)

0.84


APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidential interval; MAXICU, maximum body temperature during an ICU stay; NSAIDs, non-steroid anti-inflammatory drugs

Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group et al. Critical Care 2012 16:R33   doi:10.1186/cc11211

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