Table 5 |
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|
Multivariate logistic analysis for 28-day mortality in patients with lowest body temperature > 35°C |
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|
Patients with sepsis (N = 507) |
Patients without sepsis (N = 715) |
|||
|
|
||||
|
Adjusted odds ratio (95% CI) |
P-value |
Adjusted odds ratio (95% CI) |
P-value |
|
|
|
||||
|
Age (y.o., IQR) |
1.02 (1.00, 1.03) |
0.08 |
1.01 (0.98, 1.05) |
0.52 |
|
APACHE (IQR) |
1.07 (1.03, 1.11) |
< 0.001 |
1.20 (1.11, 1.30) |
< 0.001 |
|
Postoperative admission n (%) |
0.79 (0.32, 1.91) |
0.59 |
0.57 (0.21, 1.52) |
0.26 |
|
Mechanical ventilation requirement n (%) |
1.76 (0.98, 3.14) |
0.06 |
3.49 (1.14, 10.7) |
0.03 |
|
Cardiac or vascular diseases |
0.85 (0.39, 1.82) |
0.67 |
0.73 (0.24, 2.21) |
0.57 |
|
Thoracic or respiratory diseases |
1.23 (0.66, 2.28) |
0.51 |
1.24 (0.40, 3.78) |
0.71 |
|
|
||||
|
MAXICU |
||||
|
37.5°C to 38.4°C (vs. 36.5°C to 37.4°C) |
0.42 (0.20, 0.88) |
0.02 |
3.18 (0.78, 12.9) |
0.11 |
|
38.5°C to 39.4°C (vs. 36.5°C to 37.4°C) |
0.60 (0.25, 1.43) |
0.25 |
7.49 (1.47, 38.1) |
0.02 |
|
≥ 39.5°C (vs. 36.5°C to 37.4°C) |
0.59 (0.21, 1.68) |
0.32 |
11.7 (1.58, 87.0) |
0.02 |
|
|
||||
|
NSAIDs |
2.48 (1.02, 6.01) |
0.04 |
0.26 (0.032, 2.19) |
0.22 |
|
Acetaminophen |
1.95 (1.06, 3.57) |
0.03 |
0.61 (0.23, 1.61) |
0.32 |
|
Cooling |
1.23 (0.69, 2.21) |
0.47 |
1.26 (0.14, 11.0) |
0.84 |
|
|
||||
|
APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidential interval; MAXICU, maximum body temperature during an ICU stay; NSAIDs, non-steroid anti-inflammatory drugs |
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|
Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group et al. Critical Care 2012 16:R33 doi:10.1186/cc11211 |
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