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Highly Accessed Commentary

Good and bad fever

Jean-Marc Cavaillon

Author Affiliations

Unit of Cytokines & Inflammation, Department of Infection and Epidemiology, Institut Pasteur, 28 rue Dr Roux, F-75015 Paris, France

Critical Care 2012, 16:119  doi:10.1186/cc11237


See related research by Egi et al., http://ccforum.com/content/16/1/R33

Published: 20 March 2012

Abstract

Fever is considered a key actor of innate immunity aimed to fight infection. A new investigation reports an association of the use of antipyretic drugs with poorer outcome among patients with sepsis. In contrast, high temperature in non-infectious intensive care patients is associated with higher mortality.